First ladies and gentlemen of Panama
First Lady and First Gentleman of Panama are unofficial titles traditionally held by the wife or husband of the president of Panama.
List
The following is an incomplete list of first ladies and gentlemen of Panama.| No. | Portrait | Name | President | Birth | Death | Period |
| 1 | María de la Ossa de Amador | Manuel Amador Guerrero | March 1, 1855 | July 5, 1948 | February 20, 1904 – October 1, 1908 | |
| Manuela Jované Aguilar y Távara | José Domingo de Obaldía | 1887 | ||||
| Josefa Jované Aguilar y Távara | José Domingo de Obaldía | October 1, 1908 – March 1, 1910 | ||||
| Rita Barsallo de Mendoza | Carlos Antonio Mendoza | March 1, 1910 – October 1, 1910 | ||||
| Teodolinda Briceño de Boyd | Federico Boyd | October 1, 1910 - October 5, 1910 | ||||
| Matilde Esperanza Picón Herrera | Pablo Arosemena | October 5, 1910 – October 1, 1912 | ||||
| Eva Paniza Arosemena | Belisario Porras | |||||
| Alicia Castro Gutiérrez de Porras | Belisario Porras | October 1, 1912 - October 1, 1916 | ||||
| Diana Dutary Pérez | Ramón Maximiliano Valdés | October 1, 1916 – June 3, 1918 | ||||
| Kerima Gutiérrez de Díaz | Pedro Antonio Díaz | October 1, 1918 - October 12, 1918 | ||||
| Alicia Castro Gutiérrez de Porras | Belisario Porras | October 12, 1918 - January 30, 1920 | ||||
| Oderay Arango de Lefevre | Ernesto T. Lefevre | January 30, 1920 - October 1, 1920 | ||||
| Ofelina Remón de Chiari | Rodolfo Chiari | October 1, 1924 – October 1, 1928 | ||||
| Hersilia Arias de Arosemena | Florencio Harmodio Arosemena | October 1, 1928 - January 3, 1931 | ||||
| Rosario Guardia de Arias | Harmodio Arias Madrid | January 3, 1931 - January 16, 1931 | ||||
| Amelia Lyons de Alfaro | Ricardo J. Alfaro | December 15, 1883 | November 27, 1973 | January 16, 1931 - June 5, 1932 | ||
| Rosario Guardia de Arias | Harmodio Arias Madrid | June 5, 1932 - October 1, 1936 | ||||
| Malvina Galindo de Arosemena | Juan Demóstenes Arosemena | October 1, 1936 - December 16, 1939 | ||||
| Adela Moré de Fernández | Ezequiel Fernández Jaén | December 16, 1939 - December 18, 1940 | ||||
| Raquel de la Guardia de Boyd | Augusto Samuel Boyd | December 18, 1940 - October 1, 1940 | ||||
| Ana Matilde Linares de Arias | Arnulfo Arias Madrid | October 1, 1940 - October 9, 1941 | ||||
| Vacant | Ricardo de la Guardia | October 9, 1941 - March 4, 1943 | ||||
| Carmen Estripeaut de la Guardia | Ricardo de la Guardia | March 4, 1943 - June 15, 1945 | ||||
| Beatriz de la Guardia de Jiménez | Enrique A. Jiménez | June 15, 1945 - August 7, 1948 | ||||
| Celia Quelquejeu de Díaz | Domingo Díaz Arosemena | August 7, 1948 - July 28, 1949 | ||||
| Isabel Icaza de Chanis | Daniel Chanis Pinzón | July 28, 1949 - November 25, 1949 | ||||
| Cecilia Orillac de Chiari | Roberto F. Chiari | November 20, 1949 - November 24, 1949 | ||||
| Ana Matilde Linares de Arias | Arnulfo Arias Madrid | November 24, 1949 - May 9, 1951 | ||||
| Heliodora Arosemena de Arosemena | Alcibíades Arosemena | May 9, 1951 - October 1, 1952 | ||||
| Cecilia Pinel de Remón | José Remón Cantera | October 1, 1952 - January 2, 1955 | ||||
| Olga Arias de Arias | Ricardo Arias Espinosa | March 29, 1955 - October 1, 1956 | ||||
| Mercedes Galindo de la Guardia | Ernesto de la Guardia | October 1, 1956 - October 1, 1960 | ||||
| Cecilia Orillac de Chiari | Roberto F. Chiari | October 1, 1960 - October 1, 1964 | ||||
| Petita Saa de Robles | Marco Aurelio Robles | October 1, 1964 - October 1, 1968 | ||||
| Mireya Moscoso de Arias | Arnulfo Arias Madrid | July 1, 1946 | October 1, 1968 - October 11, 1968 | |||
| Elizabeth "Fanny" Rojer de Lakas | Demetrio B. Lakas | December 19, 1969 – October 11, 1978 | ||||
| Adela Ruiz de Royo | Arístides Royo | December 15, 1943 | June 19, 2019 | October 11, 1978 – July 31, 1982 | ||
| Mercedes Martinez de la Espriella | Ricardo de la Espriella | July 31, 1982 – February 13, 1984 | ||||
| Luzmila Arosemena de Illueca | Jorge Illueca | February 13, 1984 - October 11, 1984 | ||||
| María Consuelo Rivera de Ardito Barletta | Nicolás Ardito Barletta | October 11, 1984 - September 27, 1985 | ||||
| Mariela de Delvalle | Eric Arturo Delvalle | September 28, 1985 - February 26, 1988 | ||||
| Marcela Endara Cambra | Guillermo Endara | June, 1989 | December 20, 1989 - June 11, 1990 | |||
| Ana Mae Diaz | Guillermo Endara | May 16, 1967 | June 11, 1990 – September 1, 1994 | |||
| Dora Boyd de Perez Balladares | Ernesto Pérez Balladares | October 11, 1948 | September 1, 1994 – September 1, 1999 | |||
| Ruby Moscoso | Mireya Moscoso | September 22, 1941 | January 7, 2022 | September 1, 1999 – September 1, 2004 | ||
| Vivian Fernández | Martín Torrijos | March 25, 1966 | September 1, 2004 – July 1, 2009 | |||
| Marta Linares | Ricardo Martinelli | September 2, 1956 | July 1, 2009 - July 1, 2014 | |||
| Lorena Castillo | Juan Carlos Varela | July 31, 1968 | July 1, 2014 - July 1, 2019 | |||
| Yazmín Colón de Cortizo | Laurentino Cortizo | July 31, 1959 | July 1, 2019 - July 1, 2024 | |||
| Maricel Cohen de Mulino | José Raúl Mulino | July 1, 2024 - Present |