| Rank | Title | Distributor | Worldwide gross | Year | References |
| 1 | Avatar: The Way of Water | 20th Century | $2,320,250,281 | 2022 | |
| 2 | Ne Zha 2 | Beijing Enlight Pictures | $2,259,822,417 | 2025 | |
| 3 | Spider-Man: No Way Home | Sony | $1,922,598,800 | 2021 | |
| 4 | Zootopia 2 | Disney | $1,745,533,159 | 2025 | |
| 5 | Inside Out 2 | Disney | $1,698,863,816 | 2024 | |
| 6 | Top Gun: Maverick | Paramount | $1,495,696,292 | 2022 | |
| 7 | Barbie | Warner Bros. | $1,445,638,421 | 2023 | |
| 8 | Avatar: Fire and Ash | 20th Century | $1,379,620,247 | 2025 | |
| 9 | The Super Mario Bros. Movie | Universal | $1,362,027,222 | 2023 | |
| 10 | Deadpool & Wolverine | Disney | $1,338,073,645 | 2024 | |
| 11 | Moana 2 | Disney | $1,059,242,164 | 2024 | |
| 12 | Lilo & Stitch | Disney | $1,038,027,526 | 2025 | |
| 13 | Jurassic World: Dominion | Universal | $1,003,700,604 | 2022 | |
| 14 | Despicable Me 4 | Universal | $971,028,338 | 2024 | |
| 15 | Oppenheimer | Universal | $970,506,816 | 2023 | |
| 16 | A Minecraft Movie | Warner Bros. | $958,287,780 | 2025 | |
| 17 | Doctor Strange in the Multiverse of Madness | Disney | $955,775,805 | 2022 | |
| 18 | Minions: The Rise of Gru | Universal | $939,628,210 | 2022 | |
| 19 | The Battle at Lake Changjin | Huaxia Film Distribution | $902,540,935 | 2021 | |
| 20 | Jurassic World Rebirth | Universal | $869,146,189 | 2025 | |
| 21 | Black Panther: Wakanda Forever | Disney | $859,208,836 | 2022 | |
| 22 | Guardians of the Galaxy Vol. 3 | Disney | $845,555,777 | 2023 | |
| 23 | Hi, Mom | Lian Ray Pictures | $841,674,419 | 2021 | |
| 24 | Demon Slayer: Kimetsu no Yaiba - The Movie: Infinity Castle | Toho / Aniplex | $778,939,527 | 2025 | |
| 25 | No Time to Die | MGM / Universal | $774,153,007 | 2021 | |
| 26 | The Batman | Warner Bros. | $770,962,583 | 2022 | |
| 27 | Thor: Love and Thunder | Disney | $760,928,081 | 2022 | |
| 28 | Wicked | Universal | $756,401,043 | 2024 | |
| 29 | F9 | Universal | $726,229,501 | 2021 | |
| 30 | Mufasa: The Lion King | Disney | $722,631,756 | 2024 | |
| 31 | Dune: Part Two | Warner Bros. | $714,711,520 | 2024 | |
| 32 | Fast X | Universal | $714,566,116 | 2023 | |
| 33 | Spider-Man: Across the Spider-Verse | Sony | $690,615,475 | 2023 | |
| 34 | Detective Chinatown 3 | Wanda Pictures | $686,257,563 | 2021 | |
| 35 | How to Train Your Dragon | Universal | $636,351,148 | 2025 | |
| 36 | Full River Red | | $634,631,282 | 2023 | |
| 37 | Wonka | Warner Bros. | $632,302,312 | 2023 | |
| 38 | F1: The Movie | Warner Bros. / Apple | $631,742,436 | 2025 | |
| 39 | The Battle at Lake Changjin II | Huaxia Film Distribution | $626,571,697 | 2022 | |
| 40 | Superman | Warner Bros. | $616,823,803 | 2025 | |
| 41 | The Wandering Earth 2 | China Film Group Corporation | $604,460,538 | 2023 | |
| 42 | | Paramount | $598,767,057 | 2025 | |
| 43 | Godzilla x Kong: The New Empire | Warner Bros. / Toho | $572,305,338 | 2024 | |
| 44 | The Little Mermaid | Disney | $569,626,289 | 2023 | |
| 45 | Mission: Impossible – Dead Reckoning Part One | Paramount | $567,535,383 | 2023 | |
| 46 | Kung Fu Panda 4 | Universal | $547,946,617 | 2024 | |
| 47 | No More Bets | Mega Films Distribution | $528,487,347 | 2023 | |
| 48 | Wicked: For Good | Universal | $526,548,284 | 2025 | |
| 49 | The Fantastic Four: First Steps | Disney | $521,858,728 | 2025 | |
| 50 | Detective Chinatown 1900 | Wanda Pictures | $508,922,947 | 2025 | |