| Release Date | Title | Platform | Genre | |
| January 1 | FlatOut 2 | OSX | | |
| January 2 | Metal Slug 3 | XBLA | | |
| January 3 | Rune Factory 2: A Fantasy Harvest Moon | DS | | |
| January 8 | Brain Challenge | DS | | |
| January 8 | Harvey Birdman: Attorney at Law | PS2, PSP, Wii | | |
| January 8 | Jackass: The Game | DS | | |
| January 8 | Kingdom Under Fire: Circle of Doom | X360 | | |
| January 8 | Sonic Riders: Zero Gravity | PS2, Wii | | |
| January 9 | Omega Five | XBLA | | |
| January 15 | CSI: Hard Evidence | Wii | | |
| January 15 | Nanostray 2 | DS | | |
| January 15 | Nitrobike | Wii | | |
| January 15 | Samurai Warriors: Katana | Wii | | |
| January 16 | Rail Simulator | WIN | | |
| January 17 | Mario & Sonic at the Olympic Games | DS | | |
| January 17 | Tori-Emaki | PS3 | | |
| January 21 | Advance Wars: Days of Ruin | DS | | |
| January 22 | Burnout Paradise | PS3, X360 | | |
| January 22 | No More Heroes | Wii | | |
| January 22 | Pirates of the Burning Sea | WIN | | |
| January 24 | PixelJunk Monsters | PSN | | |
| January 29 | The Sims Castaway Stories | WIN, OSX | | |
| January 30 | Rez HD | XBLA | | |
| January 31 | Disgaea 3: Absence of Justice | PS3 | | |
| January 31 | Super Smash Bros. Brawl | Wii | | |
| January 31 | We Ski | Wii | | |
| February 4 | Sins of a Solar Empire | WIN | | |
| February 4 | Zoo Tycoon 2 DS | DS | | |
| February 5 | Assassin's Creed: Altaïr's Chronicles | DS | | |
| February 5 | Culdcept Saga | X360 | | |
| February 5 | Devil May Cry 4 | PS3, X360 | | |
| February 5 | Turok | PS3, X360 | | |
| February 7 | The Club | PS3, WIN, X360 | | |
| February 7 | Go! Puzzle | PS3, PSP | | |
| February 7 | Grand Chase | WIN | | |
| February 7 | L the Prologue to Death Note -Rasen no Wana- | DS | | |
| February 8 | Agatha Christie: And Then There Were None | Wii | | |
| February 12 | Conflict: Denied Ops | PS3, WIN, X360 | | |
| February 12 | Dark Messiah of Might and Magic | X360 | | |
| February 12 | Innocent Life: A Futuristic Harvest Moon | PS2 | | |
| February 12 | Jumper: Griffin's Story | PS2, PS3, Wii, X360 | | |
| February 12 | Lost Odyssey | X360 | | |
| February 12 | Penumbra: Black Plague | LIN, WIN | | |
| February 12 | Wipeout Pulse | PSP | | |
| February 14 | Dream Chronicles 2: The Eternal Maze | WIN | | |
| February 18 | MX vs. ATV: Untamed | Wii | | |
| February 18 | Need for Speed: ProStreet | PSP | | |
| February 19 | Dragon Quest Swords: The Masked Queen and the Tower of Mirrors | Wii | | |
| February 19 | Dungeon Explorer: Warriors of Ancient Arts | DS, PSP | | |
| February 19 | Dynasty Warriors 6 | PS3, X360 | | |
| February 19 | Pimp My Ride | Wii | | |
| February 19 | The History Channel: Battle for the Pacific | PS3 | | |
| February 20 | N+ | XBLA | | |
| February 21 | Lost Planet: Extreme Condition | PS3 | | |
| February 21 | Space Invaders Extreme | DS, PSP | | |
| February 22 | Barnyard Blast: Swine of the Night | DS | | |
| February 25 | Destroy All Humans! Big Willy Unleashed | Wii | | |
| February 25 | Frontlines: Fuel of War | WIN, X360 | | |
| February 26 | Bubble Bobble Double Shot | DS | | |
| February 26 | Lost: Via Domus | PS3, WIN, X360 | | |
| February 26 | Naruto: Ninja Destiny | DS | | |
| February 26 | Pinball Hall of Fame: The Williams Collection | PS2, PSP, Wii | | |
| February 26 | Turning Point: Fall of Liberty | PS3, WIN, X360 | | |
| February 26 | Universe at War: Earth Assault | X360 | | |
| February 27 | Blokus Portable: Steambot Championship | PSP | | |
| February 27 | Triggerheart Exelica | XBLA | | |
| February 28 | The Idolmaster Live For You! | X360 | | |
| February 28 | The Sims 2: FreeTime | WIN | | |
| March 1 | Trials 2: Second Edition | WIN | | |
| March 3 | Bully: Scholarship Edition | Wii, X360 | | |
| March 3 | Major League Baseball 2K8 | PS2, PS3, PSP, Wii, X360 | | |
| March 4 | Anno 1701: Dawn of Discovery | DS | | |
| March 4 | Army of Two | PS3, X360 | | |
| March 4 | Eco Creatures: Save the Forest | DS | | |
| March 4 | God of War: Chains of Olympus | PSP | | |
| March 4 | MLB 08: The Show | PS2, PS3, PSP | | |
| March 4 | Mystery Dungeon: Shiren the Wanderer | DS | | |
| March 4 | Ninja Reflex | Wii | | |
| March 4 | Silent Hill: Origins | PS2 | | |
| March 5 | Harvest: Massive Encounter | OSX, WIN | | |
| March 5 | Rocketmen: Axis of Evil | XBLA | | |
| March 5 | Warhammer 40,000: Dawn of War: Soulstorm | WIN | | |
| March 6 | Flow | PSP | | |
| March 6 | Yakuza: Kenzan! | PS3 | | |
| March 6 | Rocketmen: Axis of Evil | PSN | | |
| March 9 | Super Smash Bros. Brawl | Wii | | |
| March 10 | Worms: A Space Oddity | Wii | | |
| March 11 | Buzz!: The Hollywood Quiz | PS2 | | |
| March 11 | Condemned 2: Bloodshot | X360 | | |
| March 11 | George of the Jungle and the Search for the Secret | DS, PS2, Wii | | |
| March 11 | Insecticide | DS, WIN | | |
| March 11 | Ratchet & Clank: Size Matters | PS2 | | |
| March 11 | The House of the Dead 2 & 3 Return | Wii | | |
| March 11 | Wild Arms XF | PSP | | |
| March 12 | Bliss Island | XBLA | | |
| March 18 | Condemned 2: Bloodshot | PS3 | | |
| March 18 | Enemy Territory: Quake Wars | OSX | | |
| March 18 | Everybody's Golf 5 | PS3 | | |
| March 18 | Pro Evolution Soccer 2008 | Wii | | |
| March 18 | Sega Superstars Tennis | DS, PS2, PS3, Wii, X360 | | |
| March 18 | Target: Terror | Wii | | |
| March 18 | Tom Clancy's Rainbow Six: Vegas 2 | PS3, WIN, X360 | | |
| March 19 | Deca Sports | Wii | | |
| March 19 | SimCity DS 2 | DS | | |
| March 20 | Pokémon Ranger: Shadows of Almia | DS | | |
| March 24 | Command & Conquer 3: Kane's Wrath | WIN, X360 | | |
| March 24 | Crisis Core: Final Fantasy VII | PSP | | |
| March 24 | M&M's Kart Racing | DS | | |
| March 25 | ObsCure II | Wii | | |
| March 25 | Opoona | Wii | | |
| March 25 | Viking: Battle for Asgard | PS3, X360 | | |
| March 26 | GoPets: Vacation Island | DS | | |
| March 28 | Dark Sector | PS3, X360 | | |
| March 28 | Ninja Gaiden Dragon Sword | DS | | |
| April 1 | Brothers in Arms: Road to Hill 30 | Wii | | |
| April 2 | Mr. Driller Online | XBLA | | |
| April 2 | Star Ocean: Second Evolution | PSP | | |
| April 4 | FlatOut: Head On | PSP | | |
| April 8 | Assassin's Creed | WIN | | |
| April 8 | Baroque | PS2, Wii | | |
| April 8 | Supreme Commander | X360 | | |
| April 9 | Ikaruga | XBLA | | |
| April 10 | Arcana Heart | PS2 | | |
| April 10 | Mario Kart Wii | Wii | | |
| April 15 | Ōkami | Wii | | |
| April 15 | Rondo of Swords | DS | | |
| April 15 | Teenage Zombies: Invasion of the Alien Brain Thingys! | DS | | |
| April 16 | TrackMania Nations Forever | WIN | | |
| April 18 | Legacy of Ys: Books I & II | DS | | |
| April 20 | Pokémon Mystery Dungeon: Explorers of Time and Explorers of Darkness | DS | | |
| April 21 | Metal Arms: Glitch in the System | X360 | | |
| April 22 | High School Musical 2: Work This Out! | DS | | |
| April 22 | Persona 3 FES | PS2 | | |
| April 22 | The World Ends with You | DS | | |
| April 22 | Turok | WIN | | |
| April 24 | Valkyria Chronicles | PS3 | | |
| April 25 | King's Bounty: The Legend | WIN | | |
| April 27 | Mario Kart Wii | Wii | | |
| April 29 | Grand Theft Auto IV | PS3, X360 | | |
| April 29 | Let's Yoga | DS | | |
| April 30 | Galactic Civilizations II: Twilight of the Arnor | WIN | | |
| May 1 | Echochrome | PSN, PSP | | |
| May 2 | Iron Man | DS, PS2, PS3, PSP, Wii, WIN, X360 | | |
| May 5 | Chameleon | PSP | | |
| May 5 | Crosswords DS | DS | | |
| May 5 | The Destiny of Zorro | Wii | | |
| May 6 | Boom Blox | MOBI, Wii | | |
| May 6 | Speed Racer | DS, Wii | | |
| May 12 | LostWinds | WiiWare | | |
| May 13 | Castle of Shikigami III | Wii | | |
| May 13 | Drone Tactics | DS | | |
| May 13 | The Chronicles of Narnia: Prince Caspian | DS, PS2, PS3, PSP, Wii, WIN, X360 | | |
| May 15 | Dark Mist | PSN | | |
| May 15 | Luminous Arc 2: Will | DS | | |
| May 17 | Monster Madness: Grave Danger | PS3 | | |
| May 19 | Critter Round-Up | WiiWare | | |
| May 20 | Age of Conan: Hyborian Adventures | WIN | | |
| May 20 | SingStar | PS3 | | |
| May 21 | Penny Arcade Adventures: On the Rain-Slick Precipice of Darkness | LIN, OSX, WIN, X360 | | |
| May 21 | Wii Fit | Wii | | |
| May 23 | Haze | PS3 | | |
| May 26 | Cross Edge | PS3 | | |
| May 26 | Dr. Mario Online Rx | WiiWare | | |
| May 27 | Death Jr. II: Root of Evil | Wii | | |
| May 27 | Emergency Heroes | Wii | | |
| May 27 | Enemy Territory: Quake Wars | PS3, X360 | | |
| May 27 | Super Dodgeball Brawlers | DS | | |
| May 28 | Mass Effect | WIN | | |
| May 30 | Commando: Steel Disaster | DS | | |
| May 30 | Race Driver: Grid | PS3, WIN, X360 | | |
| June 3 | Chaos Wars | PS2 | | |
| June 3 | Hot Shots Golf: Open Tee 2' | PSP | | |
| June 3 | Kung Fu Panda | DS, PS2, PS3, Wii, WIN, X360 | | |
| June 3 | Lego Indiana Jones: The Original Adventures | DS, PS2, PS3, PSP, Wii, WIN, XBOX, X360 | | |
| June 3 | Ninja Gaiden II | X360 | | |
| June 3 | Robert Ludlum's The Bourne Conspiracy | PS3, X360 | | |
| June 3 | Summon Night: Twin Age | DS | | |
| June 4 | Roogoo | XBLA | | |
| June 5 | Dragon Ball Z: Burst Limit | PS3, X360 | | |
| June 5 | Carl²: Taking the Class | PS3, X360 | | |
| June 5 | Fushigi no Dungeon – Furai no Shiren 3: Karakuri Yashiki no Nemuri Hime | Wii | | |
| June 5 | The Incredible Hulk | DS, PS2, PS3, Wii, X360 | | |
| June 9 | My Pokémon Ranch | WiiWare | | |
| June 10 | Blast Works: Build, Trade, Destroy | Wii | | |
| June 10 | Don King Presents: Prizefighter | X360 | | |
| June 10 | Dragon Ball Z: Burst Limit | PS3, X360 | | |
| June 10 | NASCAR 09 | PS2, PS3, X360 | | |
| June 10 | Total Drama | WIN, PS2, PS3, DS, Wii, X360 | | |
| June 10 | The Incredible Hulk | WIN | | |
| June 11 | Frogger 2 | XBLA | | |
| June 11 | Jake Hunter: Detective Chronicles | DS | | |
| June 12 | Metal Gear Solid 4: Guns of the Patriots | PS3 | | |
| June 13 | Civilization Revolution | PS3, X360 | | |
| June 13 | Etrian Odyssey II: Heroes of Lagaard | DS | | |
| June 17 | Deadliest Catch: Alaskan Storm | X360 | | |
| June 17 | Di-Gata Defenders: Legend of the Seth | DS, PS2, PS3, X360, Wii | | |
| June 17 | Secret Agent Clank | PSP | | |
| June 17 | Supreme Ruler 2020 | WIN | | |
| June 17 | Wacky Races: Crash and Dash | DS, Wii | | |
| June 18 | Elements of Destruction | XBLA | | |
| June 18 | Fishdom | DS | | |
| June 19 | Fatal Inertia EX | PS3 | | |
| June 19 | Mario Super Sluggers | Wii | | |
| June 20 | Alone in the Dark | PS2, Wii, WIN, X360 | | |
| June 20 | Code Lyoko: Fall of X.A.N.A. | DS | | |
| June 20 | Top Spin 3 | PS3, Wii, X360 | | |
| June 22 | Guitar Hero: On Tour | DS | | |
| June 22 | Rock Band | Wii | | |
| June 23 | Battlefield: Bad Company | PS3, X360 | | |
| June 23 | Gyrostarr | WiiWare | | |
| June 23 | Top Spin 3 | DS | | |
| June 24 | WALL-E | DS, PS2, PS3, PSP, Wii, WIN, X360 | | |
| June 24 | Big Beach Sports | Wii | | |
| June 24 | Hellboy: The Science of Evil | PS3, PSP, X360 | | |
| June 24 | Mega Man Star Force 2 | DS | | |
| June 25 | Happy Tree Friends: False Alarm | X360, WIN | | |
| June 26 | Disgaea DS: Prince of the Demon World and the Red Moon | DS | | |
| June 26 | Tales of Symphonia: Dawn of the New World | Wii | | |
| June 29 | Guitar Hero: Aerosmith | PS2, PS3, Wii, X360 | | |
| June 30 | Journey to the Center of the Earth | DS | | |
| June 30 | Magnetica | WiiWare | | |
| July 1 | Elements of Destruction | WIN | | |
| July 1 | Trauma Center: Under the Knife 2 | DS | | |
| July 1 | Soul Bubbles | DS | | |
| July 3 | 1 vs. 100 | DS | | |
| July 3 | Initial D Extreme Stage | PS3 | | |
| July 3 | Nanashi no Game | DS | | |
| July 3 | Unreal Tournament 3 | X360 | | |
| July 7 | Song Summoner: The Unsung Heroes | iPod | | |
| July 7 | SPOGS Racing | WiiWare | | |
| July 7 | Zen Pinball: Rollercoaster | iOS | | |
| July 8 | Beijing 2008 | PS3, X360 | | |
| July 8 | Civilization Revolution | DS | | |
| July 8 | Devil May Cry 4 | WIN | | |
| July 8 | Final Fantasy Fables: Chocobo's Dungeon | Wii | | |
| July 10 | Critter Crunch | iOS | | |
| July 10 | Resident Evil Zero | Wii | | |
| July 10 | Persona 4 | PS2 | | |
| July 11 | Dynasty Warriors 6 | WIN | | |
| July 11 | Nancy Drew: The Phantom of Venice | WIN | | |
| July 14 | Major League Eating: The Game | Wii | | |
| July 15 | Mister Slime | DS | | |
| July 15 | NCAA Football 09 | PS2, PS3, PSP, Wii, X360 | | |
| July 15 | Space Chimps | DS, PS2, Wii, WIN, X360 | | |
| July 15 | We Love Golf! | Wii | | |
| July 16 | Double D Dodgeball | XBLA | | |
| July 17 | Dragon Quest V: Hand of the Heavenly Bride | DS | | |
| July 17 | Elefunk | PSN | | |
| July 17 | Rayman | PSN | | |
| July 17 | Tears to Tiara: Kakan no Daichi | PS3 | | |
| July 22 | New International Track & Field | DS | | |
| July 22 | The Mummy: Tomb of the Dragon Emperor | DS, PS2, PS3, Wii, X360 | | |
| July 23 | 1942: Joint Strike | XBLA | | |
| July 23 | Go! Go! Break Steady | XBLA | | |
| July 24 | 1942: Joint Strike | PSN | | |
| July 24 | Guitar Hero III: Legends of Rock | X360 | | |
| July 24 | Siren: Blood Curse | PS3 | | |
| July 24 | Wario Land: The Shake Dimension | Wii | | |
| July 28 | Pong Toss! Frat Party Games | WiiWare | | |
| July 29 | MLB Power Pros 2008 | PS2, Wii | | |
| July 29 | Soulcalibur IV | PS3, X360 | | |
| July 29 | Spectral Force 3: Innocent Rage | X360 | | |
| July 30 | Geometry Wars: Retro Evolved 2 | X360 | | |
| July 31 | Fatal Frame IV | Wii | | |
| July 31 | Phantasy Star Portable | PSP | | |
| July 31 | Rhythm Heaven | DS | | |
| August 1 | Race Driver: Grid | DS | | |
| August 4 | Reset Generation | WIN | | |
| August 4 | Wild West Guns | WiiWare | | |
| August 5 | Dance Dance Revolution: Nickelodeon Party 3 | PS2 | | |
| August 6 | Braid | XBLA | | |
| August 7 | Fire Emblem: Shadow Dragon | DS | | |
| August 7 | Hannah Montana: Spotlight World Tour | PS2 | | |
| August 7 | Tales of Vesperia | X360 | | |
| August 12 | Bangai-O Spirits | DS | | |
| August 12 | Space Siege | WIN | | |
| August 13 | Bionic Commando Rearmed | XBLA | | |
| August 13 | Madden NFL 09 | DS, PS2, PS3, PSP, Wii, X360, XBOX | | |
| August 14 | Bionic Commando Rearmed | PSN, WIN | | |
| August 19 | The Cheetah Girls: Passport to Stardom | DS | | |
| August 19 | Deadliest Catch: Alaskan Storm | WIN | | |
| August 19 | Too Human | X360 | | |
| August 21 | Ratchet & Clank Future: Quest for Booty | PS3 | | |
| August 21 | Sigma Harmonics | DS | | |
| August 22 | Inazuma Eleven | DS | | |
| August 25 | Helix | WiiWare | | |
| August 25 | MLB Power Pros 2008 | DS | | |
| August 26 | Digimon World Championship | DS | | |
| August 26 | FlatOut: Ultimate Carnage | WIN | | |
| August 26 | From the Abyss | DS | | |
| August 26 | My Chinese Coach | DS | | |
| August 26 | N+ | DS, PSP | | |
| August 26 | The Quest Trio | DS | | |
| August 26 | The Sims 2: Apartment Life | WIN | | |
| August 26 | The Sims 2: Apartment Pets | DS | | |
| August 26 | Tiger Woods PGA Tour 09 | PS2, PS3, PSP, Wii, X360 | | |
| August 27 | Castle Crashers | X360 | | |
| August 28 | Afrika | PS3 | | |
| August 28 | Asphalt 4: Elite Racing | iOS | | |
| August 28 | Captain Rainbow | Wii | | |
| August 28 | The Last Guy | PS3 | | |
| August 29 | Spy Fox in "Dry Cereal" | Wii | | |
| August 31 | Mercenaries 2: World in Flames | PS2, PS3, WIN, X360 | | |
| September 2 | Infinite Undiscovery | X360 | | |
| September 2 | Rapala Fishing Frenzy 2009 | PS3, Wii, X360 | | |
| September 2 | Vampire Rain: Altered Species | PS3 | | |
| September 2 | Viva Piñata: Trouble in Paradise | X360 | | |
| September 3 | Shred Nebula | XBLA | | |
| September 4 | Blue Dragon Plus | DS | | |
| September 5 | FaceBreaker | PS3, X360 | | |
| September 5 | S.T.A.L.K.E.R.: Clear Sky | WIN | | |
| September 5 | Spore | OSX, MOBI, DS, WIN | | |
| September 5 | Viva Piñata: Pocket Paradise | DS | | |
| September 8 | Air Traffic Chaos | DS | | |
| September 8 | Lock's Quest | DS | | |
| September 8 | NHL 2K9 | PS2, PS3, Wii, X360 | | |
| September 9 | Hell's Kitchen: The Game | DS, PS2, Wii, X360 | | |
| September 9 | The Fairly OddParents: Rules of Engagement | DS, PS2, PS3, PSP, Wii, X360 | | |
| September 9 | NHL 09 | PS3, Wii, X360 | | |
| September 9 | TNA iMPACT! | PS2, PS3, Wii, X360 | | |
| September 9 | Yakuza 2 | PS2 | | |
| September 9 | Zoids Assault | X360 | | |
| September 11 | One Piece: Unlimited Cruise: Episode 1 | Wii | | |
| September 12 | Crysis Warhead | WIN | | |
| September 13 | Pokémon Platinum | DS | | |
| September 14 | 6teen: Dude of the Living Dead | DS, PS2, PS3, PSP, Wii, WIN, X360 | | |
| September 14 | Rock Band 2 | X360 | | |
| September 15 | Drawn to Life: SpongeBob SquarePants Edition | DS | | |
| September 16 | Armored Core: For Answer | PS3, X360 | | |
| September 16 | Battle Fantasia | X360 | | |
| September 16 | Criminal Minds: Hard Conspiracy | PS3, WIN, X360 | | |
| September 16 | Crysis Warhead | WIN | | |
| September 16 | Dance Dance Revolution Hottest Party 2 | Wii | | |
| September 16 | Dance Dance Revolution X | PS2 | | |
| September 16 | Speed Racer: The Videogame | PS2 | | |
| September 16 | Star Wars: The Force Unleashed | DS, PS2, PS3, PSP, Wii | | |
| September 16 | The Witcher: Enhanced Edition | WIN | | |
| September 16 | Pure | PS3, X360, WIN | | |
| September 18 | Dragon Ball: Origins | DS | | |
| September 18 | Eternal Sonata | PS3 | | |
| September 18 | Warhammer Online: Age of Reckoning | WIN | | |
| September 19 | Igor: The Game | DS, Wii, WIN | | |
| September 22 | Civilization IV: Colonization | WIN | | |
| September 22 | De Blob | DS, Wii, WIN | | |
| September 22 | Di-Gata Defenders | DS, PS2, PS3, Wii, X360 | | |
| September 22 | Kirby Super Star Ultra | DS | | |
| September 22 | Mega Man 9 | WiiWare | | |
| September 22 | SimCity Creator | Wii | | |
| September 22 | EA Sports 08 Collection | WIN | | |
| September 23 | B-Boy | PSP | | |
| September 23 | Brothers in Arms: Double Time | Wii | | |
| September 23 | Brothers in Arms: Hell's Highway | PS3, X360 | | |
| September 23 | Buzz!: Master Quiz | PSP | | |
| September 23 | Dinosaur King | PS2, DS, Wii, X360 | | |
| September 23 | Hi Hamtaro! Little Hamsters Big Adventure | DS | | |
| September 23 | Lego Batman: The Videogame | DS, PS2, PS3, PSP, Wii, WIN, X360 | | |
| September 23 | Microsoft Tinker | WIN | | |
| September 23 | Shaun the Sheep | DS | | |
| September 23 | Time Hollow | DS | | |
| September 24 | Dragon Ball Z: Trilogy | PS2 | | |
| September 24 | Duke Nukem 3D | XBLA | | |
| September 25 | Aquanaut's Holiday: Hidden Memories | PS3 | | |
| September 25 | Cross Edge | PS3 | | |
| September 25 | Disaster: Day of Crisis | Wii | | |
| September 25 | Geon | PS3 | | |
| September 25 | Janline | X360 | | |
| September 25 | Mega Man 9 | PSN | | |
| September 25 | Sands of Destruction | DS | | |
| September 25 | Wipeout HD | PSN | | |
| September 25 | World Destruction: Michibikareshi Ishi | DS | | |
| September 30 | Silent Hill: Homecoming | PS3, WIN, X360 | | |
| September 30 | Sonic Chronicles: The Dark Brotherhood | DS | | |
| September 30 | Tornado | DS | | |
| September 30 | Unsolved Crimes | DS | | |
| October 1 | Mega Man 9 | XBLA | | |
| October 2 | Dynasty Warriors 6 | PS2 | | |
| October 2 | Ikki Tousen: Eloquent Fist | PSP | | |
| October 2 | Work Time Fun | PSN | | |
| October 4 | Meat Boy | WEB | | |
| October 5 | Fieldrunners | iOS | | |
| October 7 | Bleach: Dark Souls | DS | | |
| October 7 | Brothers in Arms: Hell's Highway | WIN | | |
| October 7 | Crash: Mind over Mutant | PS2, Wii, X360, PSP | | |
| October 7 | Crash: Mind over Mutant | DS | | |
| October 7 | Fracture | PS3, X360 | | |
| October 7 | Guilty Gear 2: Overture | X360 | | |
| October 7 | NBA Live 09 | PS2, PS3, PSP, Wii, X360 | | |
| October 7 | NBA 2K9 | PS2, PS3, Wii, X360 | | |
| October 7 | Spectrobes: Beyond the Portals | DS | | |
| October 8 | MLB Stickball | XBLA | | |
| October 8 | The Legend of Kage 2 | DS | | |
| October 9 | Linger in Shadows | PS3 | | |
| October 9 | Macross Ace Frontier | PSP | | |
| October 9 | Supersonic Acrobatic Rocket-Powered Battle-Cars | PS3 | | |
| October 9 | Snoopy DS: Let's Go Meet Snoopy and His Friends! | DS | | |
| October 13 | Avatar: The Last Airbender – Into the Inferno | DS, PS2, Wii | | |
| October 13 | Blitz: The League II | PS3, X360 | | |
| October 13 | Cubello | WiiWare | | |
| October 13 | Prey the Stars | DS | | |
| October 13 | Tak: Mojo Mistake | DS | | |
| October 13 | World of Goo | WIN, Wii | | |
| October 14 | Dead Space | PS3, X360 | | |
| October 14 | FIFA 09 | MOBI, DS, PS2, PS3, PSP, Wii, WIN, X360 | | |
| October 14 | Rock Revolution | DS, PS3, Wii, X360 | | |
| October 14 | Saints Row 2 | PS3, X360 | | |
| October 14 | SOCOM U.S. Navy SEALs: Confrontation | PS3 | | |
| October 14 | Golden Axe: Beast Rider | PS3, X360 | | |
| October 14 | Boogie Superstar | Wii | | |
| October 15 | Age of Booty | XBLA | | |
| October 16 | Culdcept DS | DS | | |
| October 16 | Nancy Drew: The Haunting of Castle Malloy | WIN | | |
| October 16 | Wii Music | Wii | | |
| October 16 | X3: Terran Conflict | WIN | | |
| October 19 | Rock Band 2 | PS3 | | |
| October 20 | Back at the Barnyard: Slop Bucket Games | DS | | |
| October 20 | Celebrity Sports Showdown | Wii | | |
| October 20 | Midnight Club: Los Angeles | PS3, X360, PSP | | |
| October 20 | NHL 09 | WIN | | |
| October 20 | Dead Space | WIN | | |
| October 20 | SpongeBob SquarePants featuring Nicktoons: Globs of Doom | PS2, Wii, DS | | |
| October 20 | The Naked Brothers Band: The Video Game | DS, PS2, Wii, WIN | | |
| October 21 | Bully: Scholarship Edition | WIN | | |
| October 21 | BioShock | PS3 | | |
| October 21 | Castlevania: Order of Ecclesia | DS | | |
| October 21 | Crash: Mind over Mutant | PSP | | |
| October 21 | Dance Dance Revolution Universe 3 | X360 | | |
| October 21 | Disney Think Fast | Wii | | |
| October 21 | Far Cry 2 | PS3, WIN, X360 | | |
| October 21 | Fable II | X360 | | |
| October 21 | Jillian Michaels' Fitness Ultimatum 2009 | Wii | | |
| October 21 | Little Red Riding Hood's Zombie BBQ | DS | | |
| October 21 | Naruto: Clash of Ninja Revolution 2 | Wii | | |
| October 21 | Spider-Man: Web of Shadows | DS, PS2, PS3, PSP, Wii, WIN, X360 | | |
| October 21 | The Legend of Spyro: Dawn of the Dragon | DS, PS2, PS3, Wii, X360 | | |
| October 21 | Transformers Animated: The Game | DS | | |
| October 21 | NBA 2K9 | WIN | | |
| October 21 | What's Cooking? with Jamie Oliver | DS | | |
| October 23 | Prince of Persia Classic | PSN | | |
| October 26 | Casper's Scare School | DS | | |
| October 26 | Guitar Hero World Tour | OSX, PS2, PS3, Wii, WIN, X360 | | |
| October 27 | MySims Kingdom | DS, Wii | | |
| October 28 | Ben 10: Alien Force | DS, PS2, PSP, Wii | | |
| October 28 | Command & Conquer: Red Alert 3 | WIN | | |
| October 28 | Dora the Explorer: Dora Saves the Snow Princess | DS, PS2, Wii | | |
| October 28 | Fallout 3 | PS3, WIN, X360 | | |
| October 28 | Go, Diego, Go!: The Great Dinosaur Rescue | DS, PS2, Wii | | |
| October 28 | Goosebumps HorrorLand | DS, PS2, Wii | | |
| October 28 | LittleBigPlanet | PS3 | | |
| October 28 | MotorStorm: Pacific Rift | PS3 | | |
| October 28 | MySims | WIN | | |
| October 28 | Ninjatown | DS | | |
| October 29 | Penny Arcade Adventures: On the Rain-Slick Precipice of Darkness – Episode 2 | LIN, OSX, WIN, X360 | | |
| October 30 | Away: Shuffle Dungeon | DS | | |
| October 30 | Valkyrie Profile: Covenant of the Plume | DS | | |
| October 31 | Master of the Monster Lair | DS | | |
| November 3 | Alien Crush Returns | WiiWare | | |
| November 4 | Bones | PS2, PS3, WIN, X360 | | |
| November 4 | Dragon Ball Z: Infinite World | PS2 | | |
| November 4 | Dragon Ball: Origins | DS | | |
| November 4 | Bratz Kidz | DS, Wii | | |
| November 4 | KORG DS-10 | DS | | |
| November 4 | Legendary | PS3, WIN, X360 | | |
| November 4 | Madagascar: Escape 2 Africa | PS3, PS2, X360, WIN, Wii, DS | | |
| November 4 | Naruto: Ultimate Ninja Storm | PS3 | | |
| November 4 | Tom Clancy's EndWar | DS, PS3, PSP, X360 | | |
| November 4 | Resistance 2 | PS3 | | |
| November 4 | Namco Museum Virtual Arcade | X360 | | |
| November 5 | Exit | DS | | |
| November 5 | Kung Fu Panda: Legendary Warriors | DS, Wii | | |
| November 7 | Gears of War 2 | X360 | | |
| November 7 | Men of War | WIN | | |
| November 7 | Sacred 2 Fallen Angel | WIN | | |
| November 10 | Pokémon Ranger: Shadows of Almia | DS | | |
| November 11 | Banjo-Kazooie: Nuts & Bolts | X360 | | |
| November 11 | Call of Duty: World at War | DS, PS3, Wii, WIN, X360, PS2 | | |
| November 11 | Command & Conquer: Red Alert 3 | X360 | | |
| November 11 | Eternal Poison | PS2 | | |
| November 11 | FaceBreaker | Wii | | |
| November 11 | Guinness World Records: The Videogame | DS, Wii | | |
| November 11 | Mirror's Edge | PS3, X360 | | |
| November 11 | WWE SmackDown vs. Raw 2009 | MOBI, DS, PS2, PS3, PSP, Wii, X360 | | |
| November 11 | Star Wars: The Clone Wars – Lightsaber Duels | Wii | | |
| November 11 | Star Wars: The Clone Wars – Jedi Alliance | DS | | |
| November 11 | Tecmo Bowl: Kickoff | DS | | |
| November 12 | Pro Evolution Soccer 2009 | PS2, PS3, PSP, Wii, WIN, X360 | | |
| November 13 | World of Warcraft: Wrath of the Lich King | WIN, OSX | | |
| November 14 | Football Manager 2009 | WIN, OSX, PSP | | |
| November 16 | Animal Crossing: City Folk | Wii | | |
| November 16 | Mortal Kombat vs. DC Universe | PS3, X360 | | |
| November 16 | Shaun White Snowboarding | PS3, Wii, WIN, X360 | | |
| November 17 | Guitar Hero On Tour: Decades | DS | | |
| November 17 | Robocalypse | DS | | |
| November 17 | Skate It | DS, Wii | | |
| November 18 | Alone in the Dark: Inferno | PS3 | | |
| November 18 | Avatar: The Last Airbender – Into the Inferno | PS3, X360 | | |
| November 18 | Bolt | DS, PS2, PS3, Wii, WIN, X360 | | |
| November 18 | Cooking Mama: World Kitchen | Wii | | |
| November 18 | Cradle of Rome | DS | | |
| November 18 | Ultimate Band | DS, Wii | | |
| November 18 | Castlevania Judgment | Wii | | |
| November 18 | Iron Chef America: Supreme Cuisine | DS | | |
| November 18 | Left 4 Dead | WIN, X360 | | |
| November 18 | Need for Speed: Undercover | MOBI, PS2, PS3, PSP, Wii, WIN, X360 | | |
| November 18 | Sonic Unleashed | PS2, PS3, Wii, X360 | | |
| November 18 | SpongeBob SquarePants featuring Nicktoons: Globs of Doom | PS3, PSP, X360 | | |
| November 18 | Tomb Raider: Underworld | DS, PS2, PS3, Wii, WIN, X360 | | |
| November 18 | Tony Hawk's Motion | DS | | |
| November 18 | Rayman Raving Rabbids: TV Party | DS, Wii | | |
| November 18 | Naruto: The Broken Bond | X360 | | |
| November 18 | CSI: NY | WIN | | |
| November 18 | You're in the Movies | X360 | | |
| November 19 | Weapon of Choice | XBLA | | |
| November 20 | Gallop & Ride | Wii | | |
| November 20 | The Last Remnant | X360 | | |
| November 21 | LocoRoco 2 | PSP | | |
| November 21 | Beyond Protocol | WIN | | |
| November 23 | Brothers in Arms: Hour of Heroes | iOS | | |
| November 25 | Chrono Trigger | DS | | |
| November 25 | Club Penguin: Elite Penguin Force | DS | | |
| November 25 | Iron Chef America: Supreme Cuisine | Wii | | |
| November 25 | Neopets Puzzle Adventure | DS | | |
| November 25 | Winter Sports 2: The Next Challenge | DS, PS2, Wii, X360 | | |
| November 27 | Patapon 2 | PSP | | |
| November 27 | Rune Factory Frontier | Wii | | |
| November 30 | Geometry Dance | PS3 | | |
| December 1 | Destroy All Humans! Path of the Furon | X360 | | |
| December 1 | Space Invaders Get Even | WiiWare | | |
| December 2 | Grand Theft Auto IV | WIN | | |
| December 2 | Kingdom Hearts Re:Chain of Memories | PS2 | | |
| December 2 | Mushroom Men: Rise of the Fungi | DS | | |
| December 2 | Mushroom Men: The Spore Wars | Wii | | |
| December 2 | Nancy Drew: The White Wolf of Icicle Creek | Wii | | |
| December 2 | Prince of Persia | PS3, X360 | | |
| December 2 | Prince of Persia: The Fallen King | DS | | |
| December 2 | Safecracker: The Ultimate Puzzle Adventure | Wii | | |
| December 4 | 428: Shibuya Scramble | Wii | | |
| December 4 | Everyday Shooter | PSP | | |
| December 4 | Rygar: The Battle of Argus | Wii | | |
| December 4 | Söldner-X: Himmelsstürmer | PSN | | |
| December 5 | X3: Reunion | LIN | | |
| December 7 | Prey | LIN | | |
| December 8 | Defense Grid: The Awakening | WIN | | |
| December 8 | Hockey Allstar Shootout | WiiWare | | |
| December 9 | Prince of Persia | WIN | | |
| December 10 | Meteos | XBLA | | |
| December 10 | PowerUp Forever | XBLA | | |
| December 11 | Elebits: The Adventures of Kai and Zero | DS | | |
| December 11 | PowerUp Forever | PSN | | |
| December 14 | I Love Katamari | iOS | | |
| December 15 | Big Kahuna Party | WiiWare | | |
| December 17 | Dash of Destruction | XBLA | | |
| December 18 | Rise of the Argonauts | PS3, WIN, X360 | | |
| December 18 | Dissidia: Final Fantasy | PSP | | |
| December 18 | Dynasty Warriors: Gundam 2 | PS2, PS3, X360 | | |
| December 18 | Suikoden Tierkreis | DS | | |
| December 18 | Tales of Hearts | DS | | |
| December 23 | Crystal Defenders | iOS | | |
| December 23 | Lumines Supernova | PS3 | | |
| December 25 | White Knight Chronicles | PS3 | | |
| December 25 | RIZ-ZOAWD | DS | | |
| December 29 | MaBoShi: The Three Shape Arcade | WiiWare | | |
| December 31 | Shin Megami Tensei: Imagine | WIN | | |