| Award | Recipient | Result |
| Ultimate Scream | 28 Weeks Later | Nomitated |
| Ultimate Scream | 300 | |
| Ultimate Scream | Battlestar Galactica | Nomitated |
| Ultimate Scream | The Descent | Nomitated |
| Ultimate Scream | Harry Potter and the Order of the Phoenix | Nomitated |
| Ultimate Scream | Heroes | Nomitated |
| Ultimate Scream | Pan's Labyrinth | Nomitated |
| Ultimate Scream | Pirates of the Caribbean: At World's End | Nomitated |
| Ultimate Scream | Spider-Man 3 | Nomitated |
| Ultimate Scream | Transformers | Nomitated |
| Best Horror Movie | 28 Weeks Later | |
| Best Horror Movie | 1408 | Nomitated |
| Best Horror Movie | The Descent | Nomitated |
| Best Horror Movie | Grindhouse | Nomitated |
| Best Horror Movie | The Host | Nomitated |
| Best Horror Movie | Hostel: Part II | Nomitated |
| Best Fantasy Movie | Harry Potter and the Order of the Phoenix | Nomitated |
| Best Fantasy Movie | Pan's Labyrinth | |
| Best Fantasy Movie | Pirates of the Caribbean: At World's End | Nomitated |
| Best Fantasy Movie | Spider-Man 3 | Nomitated |
| Best Fantasy Movie | Stardust | Nomitated |
| Best Science Fiction Movie | Children of Men | Nomitated |
| Best Science Fiction Movie | The Fountain | Nomitated |
| Best Science Fiction Movie | The Prestige | Nomitated |
| Best Science Fiction Movie | Sunshine | Nomitated |
| Best Science Fiction Movie | Transformers | |
| Best TV Show | Battlestar Galactica | Nomitated |
| Best TV Show | Doctor Who | Nomitated |
| Best TV Show | Heroes | |
| Best TV Show | Lost | Nomitated |
| Best TV Show | Masters of Horror | Nomitated |
| Best Comic Book | 30 Days of Night | |
| Best Comic Book | All-Star Superman | Nomitated |
| Best Comic Book | The Boys | Nomitated |
| Best Comic Book | Ultimate Fantastic Four | Nomitated |
| Best Comic Book | Y: The Last Man | Nomitated |
| Scream Queen | ' as ', Vacancy | |
| Scream Queen | as Chrissie, | Nomitated |
| Scream Queen | as, Grindhouse | Nomitated |
| Scream Queen | as, Grindhouse | Nomitated |
| Scream Queen | as, Hostel: Part II | Nomitated |
| Scream Queen | as, Black Christmas | Nomitated |
| Scream King | Shia LaBeouf as Kale Brecht, Disturbia | |
| Scream King | John Cusack as Mike Enslin, 1408 | Nomitated |
| Scream King | Samuel L. Jackson, Snakes on a Plane | Nomitated |
| Scream King | Angus Macfadyen as Jeff Denlon, Saw III | Nomitated |
| Scream King | Freddy Rodriguez, Grindhouse | Nomitated |
| Scream King | Luke Wilson as David Fox, Vacancy | Nomitated |
| Best Superhero | Michael Chiklis as The Thing, Fantastic Four: Rise of the Silver Surfer | Nomitated |
| Best Superhero | Chris Evans as Human Torch, Fantastic Four: Rise of the Silver Surfer | Nomitated |
| Best Superhero | Tobey Maguire as Spider-Man, Spider-Man 3 | |
| Best Superhero | Masi Oka as Hiro Nakamura, Heroes | Nomitated |
| Best Superhero | Milo Ventimiglia as Peter Petrelli, Heroes | Nomitated |
| Sexiest Superhero | Jessica Alba, Fantastic Four: Rise of the Silver Surfer | |
| Sexiest Superhero | Ali Larter, Heroes | Nomitated |
| Sexiest Superhero | Hayden Panettiere as Claire Bennet, Heroes | Nomitated |
| Fantasy Fox | Jessica Biel, The Illusionist | |
| Fantasy Fox | Kirsten Dunst, Spider-Man 3 | Nomitated |
| Fantasy Fox | Lena Headey, 300 | Nomitated |
| Fantasy Fox | Keira Knightley, Pirates of the Caribbean: At World's End | Nomitated |
| Fantasy Fox | Evangeline Lilly, Lost | Nomitated |
| Fantasy Fox | Eva Mendes, Ghost Rider | Nomitated |
| Fantasy Fox | Sienna Miller, Stardust | Nomitated |
| Fantasy Hero | Gerard Butler, 300 | Nomitated |
| Fantasy Hero | Johnny Depp, Pirates of the Caribbean: At World's End | |
| Fantasy Hero | Matthew Fox, Lost | Nomitated |
| Fantasy Hero | Edward Norton, The Illusionist | Nomitated |
| Fantasy Hero | Daniel Radcliffe, Harry Potter and the Order of the Phoenix | Nomitated |
| Sci-Fi Siren | Clare-Hope Ashitey, Children of Men | Nomitated |
| Sci-Fi Siren | Megan Fox, Transformers | |
| Sci-Fi Siren | Scarlett Johansson, The Prestige | Nomitated |
| Sci-Fi Siren | Katee Sackhoff, Battlestar Galactica | Nomitated |
| Sci-Fi Siren | Rachel Weisz, The Fountain | Nomitated |
| Sci-Fi Star | Christian Bale, The Prestige | Nomitated |
| Sci-Fi Star | Hugh Jackman, The Fountain | Nomitated |
| Sci-Fi Star | Shia LaBeouf, Transformers | |
| Sci-Fi Star | Cillian Murphy, Sunshine | Nomitated |
| Sci-Fi Star | Clive Owen, Children of Men | Nomitated |
| Best Cameo | David Bowie, The Prestige | Nomitated |
| Best Cameo | Jay Hernandez, Hostel: Part II | Nomitated |
| Best Cameo | Keith Richards, Pirates of the Caribbean: At World's End | |
| Best Cameo | Quentin Tarantino, Grindhouse | Nomitated |
| Best Cameo | Bruce Willis, Grindhouse | Nomitated |
| Breakout Performance | Clare-Hope Ashitey, Children of Men | Nomitated |
| Breakout Performance | Zoë Bell, Grindhouse | Nomitated |
| Breakout Performance | Megan Fox, Transformers | Nomitated |
| Breakout Performance | Lauren German, Hostel: Part II | Nomitated |
| Breakout Performance | Shauna MacDonald, The Descent | Nomitated |
| Breakout Performance | Hayden Panettiere, Heroes | |
| Breakout Performance | Rodrigo Santoro, 300 | Nomitated |
| Most Vile Villain | Sergi López as Captain Vidal, Pan's Labyrinth | Nomitated |
| Most Vile Villain | Michelle Pfeiffer, Stardust | Nomitated |
| Most Vile Villain | Zachary Quinto as Gabriel Gray/Sylar, Heroes | Nomitated |
| Most Vile Villain | Kurt Russell as Stuntman Mike, Grindhouse | Nomitated |
| Most Vile Villain | Rodrigo Santoro as Xerxes, 300 | Nomitated |
| Most Vile Villain | Tobin Bell and Shawnee Smith as Jigsaw Killer, Saw III | Nomitated |
| Most Vile Villain | Thomas Haden Church as Sandman, Spider-Man 3 | Nomitated |
| Most Vile Villain | Topher Grace as Eddie Brock/Venom, Spider-Man 3 | Nomitated |
| Most Vile Villain | Ralph Fiennes as Lord Voldemort, Harry Potter and the Order of the Phoenix | |
| Most Memorable Mutilation | Battle vs. the Immortals, 300 | Nomitated |
| Most Memorable Mutilation | Cranial surgery, Saw III | Nomitated |
| Most Memorable Mutilation | Dismembered in car crash, Grindhouse | |
| Most Memorable Mutilation | Eaten alive by cannibal, Hostel: Part II | Nomitated |
| Most Memorable Mutilation | Mouth sliced open and sewn back together, Pan's Labyrinth | Nomitated |
| Best Comic-to-Screen Adaptation | 300 | |
| Best Comic-to-Screen Adaptation | Fantastic Four: Rise of the Silver Surfer | Nomitated |
| Best Comic-to-Screen Adaptation | Ghost Rider | Nomitated |
| Best Comic-to-Screen Adaptation | Spider-Man 3 | Nomitated |
| Best Comic-to-Screen Adaptation | TMNT | Nomitated |
| Best Sequel | 28 Weeks Later | Nomitated |
| Best Sequel | Harry Potter and the Order of the Phoenix | |
| Best Sequel | Pirates of the Caribbean: At World's End | Nomitated |
| Best Sequel | Saw III | Nomitated |
| Best Sequel | Spider-Man 3 | Nomitated |
| "Jump-From-Your-Seat" Scene of the Year | Attack of the Uber Immortal, 300 | Nomitated |
| "Jump-From-Your-Seat" Scene of the Year | Final battle: Megatron vs. Optimus Prime, Transformers | |
| "Jump-From-Your-Seat" Scene of the Year | Mid-Air battle: Spider-Man vs. The New Goblin, Spider-Man 3 | Nomitated |
| "Jump-From-Your-Seat" Scene of the Year | The rain of arrows, 300 | Nomitated |
| "Jump-From-Your-Seat" Scene of the Year | Zombie attacks glass window, 28 Weeks Later | Nomitated |
| Best Director | Michael Bay, Transformers | Nomitated |
| Best Director | Danny Boyle, Sunshine | Nomitated |
| Best Director | Alfonso Cuarón, Children of Men | Nomitated |
| Best Director | Guillermo del Toro, Pan's Labyrinth | Nomitated |
| Best Director | Neil Marshall, The Descent | Nomitated |
| Best Director | Eli Roth, Hostel: Part II | Nomitated |
| Best Director | Zack Snyder, 300 | Nomitated |
| Best Director | Sam Raimi, Spider-Man 3 | Nomitated |
| Best Director | Quentin Tarantino & Robert Rodriguez, Grindhouse | |
| Best Scream-Play | 300 written by Zack Snyder and Kurt Johnstad | Nomitated |
| Best Scream-Play | Children of Men written by Alfonso Cuarón, Timothy J. Sexton, David Arata, Mark Fergus, and Hawke Ostby | Nomitated |
| Best Scream-Play | Grindhouse written by Robert Rodriguez, Quentin Tarantino, Jeff Rendell, Eli Roth, Edgar Wright, and Rob Zombie | |
| Best Scream-Play | The Descent written by Neil Marshall | Nomitated |
| Best Scream-Play | Pan's Labyrinth written by Guillermo del Toro | Nomitated |
| Best Scream-Play | Sunshine written by Alex Garland | Nomitated |
| Best F/X | 300 | Nomitated |
| Best F/X | Harry Potter and the Order of the Phoenix | Nomitated |
| Best F/X | Pirates of the Caribbean: At World's End | Nomitated |
| Best F/X | Spider-Man 3 | Nomitated |
| Best F/X | Transformers | |
| Best Foreign Movie | Cello | Nomitated |
| Best Foreign Movie | Death Note | Nomitated |
| Best Foreign Movie | The Host | Nomitated |
| Best Foreign Movie | Initial D | Nomitated |
| Best Foreign Movie | Pan's Labyrinth | |
| Best Comic Book Writer | Brian Michael Bendis, Civil War: The Initiative / Daredevil / New Avengers | Nomitated |
| Best Comic Book Writer | Garth Ennis, Punisher: Max / The Boys / Ghost Rider / Chronicles of Wormwood / Midnight | Nomitated |
| Best Comic Book Writer | Frank Miller, All Star Batman & Robin, the Boy Wonder / Frank Miller's RoboCop | |
| Best Comic Book Writer | Alan Moore, Lost Girls / Yuggoth Cultures | Nomitated |
| Best Comic Book Writer | Brian K. Vaughn, Ex Machina / Runaways / Y: The Last Man | Nomitated |
| Best Comic Book Artist | John Cassady, Astonishing X-Men | |
| Best Comic Book Artist | Darwyn Cook, The Spirit | Nomitated |
| Best Comic Book Artist | Pia Guerra, Y: The Last Man | Nomitated |
| Best Comic Book Artist | Steve McNiven, Civil War | Nomitated |
| Best Comic Book Artist | Ben Templesmith, Wormwood: Gentleman Corpse/Fell | Nomitated |
| Best Screen-to-Comic Adaptation | 28 Days Later: The Aftermath | |
| Best Screen-to-Comic Adaptation | Army of Darkness | Nomitated |
| Best Screen-to-Comic Adaptation | Frank Miller's RoboCop | Nomitated |
| Best Screen-to-Comic Adaptation | George A. Romero's Night of the Living Dead: Back from the Grave | Nomitated |
| Best Screen-to-Comic Adaptation | The Hills Have Eyes: The Beginning | Nomitated |
| Most Shocking Comic Book Twist | Alice in Wonderland and Dorothy from Oz have lesbian sex!, Lost Girls | Nomitated |
| Most Shocking Comic Book Twist | Captain America dies!, Captain America | |
| Most Shocking Comic Book Twist | Peter Parker reveals that he is Spider-Man!, Civil War | Nomitated |
| Most Shocking Comic Book Twist | Sabretooth is beheaded by Wolverine!, Wolverine | Nomitated |
| Most Shocking Comic Book Twist | Superman is killed by Superboy-Prime!, Infinite Crisis | Nomitated |