Protein Biophysics Explains Why Highly Abundant Proteins Evolve Slowly
Protein Biophysics Explains Why Highly Abundant Proteins Evolve Slowly is a scholarly work by Eugene I. Shakhnovich and Adrian Serohijos, published in 2012 in ''Cell Reports''. The main subjects of the publication include genome, protein structure prediction, mutation rate, phylogenetics, abundance, rate of evolution, divergence, evolutionary biology, computational biology, protein folding, Genome evolution, molecular evolution, RNA sequencing, biophysics, evolutionary dynamics, and biology. The consistent observation across all kingdoms of life that highly abundant proteins evolve slowly demonstrates that cellular abundance is a key determinant of protein evolutionary rate.