Optimization of multiple‐sequence alignment based on multiple‐structure alignment
Optimization of multiple‐sequence alignment based on multiple‐structure alignment is a scholarly work by Ruth Nussinov, Maxim Shatsky, and Haim Wolfson, published in 2006 in ''Proteins''. The main subjects of the publication include biological sequence, glycosylation, artificial intelligence, computation, protein structure, protein structure prediction, protein primary structure, sequence analysis, Alignment-free sequence analysis, computer science, structural alignment, computational biology, multiple sequence alignment, algorithm, and sequence alignment. The authors demonstrate the usefulness of the method in three applications: 1) computing more accurate multiple‐sequence alignments, 2) analyzing protein conformational changes, and 3) computation of amino acid structure‐sequence conservation with application to protein–protein docking prediction.