Homology-extended sequence alignment
Homology-extended sequence alignment is a scholarly work by Jaap Heringa and Jens Kleinjung, published in 2005 in ''Nucleic Acids Research''. The main subjects of the publication include biology, sequencing, set, natural product, Alignment-free sequence analysis, RNA sequencing, sequence homology, structural alignment, multiple sequence alignment, Threading, Smith–Waterman algorithm, protein structure prediction, position, pattern recognition, sequence alignment, homology modeling, genetics, computational biology, homology, biological sequence, and artificial intelligence. The authors present a profile-profile multiple alignment strategy that uses database searching to collect homologues for each sequence in a given set, in order to enrich their available evolutionary information for the alignment.