Mutation Rates and Selection on Synonymous Mutations in SARS-CoV-2
Mutation Rates and Selection on Synonymous Mutations in SARS-CoV-2 is a scholarly work, published in 2021 in ''Genome Biology and Evolution''. The main subjects of the publication include evolutionary biology, neutral theory of molecular evolution, RNA silencing, silent mutation, mutation rate, genome, selection (genetic algorithm), mutation, purifying selection, glossary of archaeology, COVID-19, gene, SARS-CoV-2, sequencing, evolution of ageing, evolutionary dynamics, genetics, Synonymous substitution, biology, and whole genome sequencing. The authors highlight and address some common genome sequence analysis pitfalls that can lead to inaccurate inference of mutation rates and selection, such as ignoring skews in the genetic code, not accounting for recurrent mutations, and assuming evolutionary equilibrium.