List of EC numbers (EC 3)

This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. All official information is tabulated at the website of the committee. The database is developed and maintained by Andrew McDonald.

EC 3.1: Acting on Ester Bonds

EC 3.1.7: Diphosphoric Monoester Hydrolases

: prenyl-diphosphatase
: guanosine-3′,5′-bis(diphosphate) 3′-diphosphatase
: monoterpenyl-diphosphatase
EC 3.1.7.4: Now recognized as two enzymes, copal-8-ol diphosphate synthase and, sclareol synthase
: geranylgeranyl diphosphate diphosphatase
: farnesyl diphosphatase
EC 3.1.7.7: Now, -drimenol synthase
EC 3.1.7.8: Now known to be a partial activity of, adenosine tuberculosinyltransferase.
EC 3.1.7.9: Now known to be a partial activity of, adenosine tuberculosinyltransferase
: (13E)-labda-7,13-dien-15-ol synthase
: geranyl diphosphate diphosphatase
: (+)-kolavelool synthase

EC 3.1.8: Phosphoric Triester Hydrolases

EC 3.1.11: Exodeoxyribonucleases Producing 5'-Phosphomonoesters

: exodeoxyribonuclease I
: exodeoxyribonuclease III
: exodeoxyribonuclease (lambda-induced)
: exodeoxyribonuclease (phage SP₃-induced)
: exodeoxyribonuclease V
: exodeoxyribonuclease VII
EC 3.1.11.7: Now, adenosine-5′-diphospho-5′- diphosphatase
EC 3.1.11.8: Now, guanosine-5′-diphospho-5′- diphosphatase

EC 3.1.13: Exoribonucleases Producing 5'-Phosphomonoesters

EC 3.1.14: Exoribonucleases Producing 3'-Phosphomonoesters

: yeast ribonuclease

EC 3.1.15: Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 5'-Phosphomonoesters

: venom exonuclease

EC 3.1.16: Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters

: spleen exonuclease

EC 3.1.21: Endodeoxyribonucleases Producing 5'-Phosphomonoesters

: deoxyribonuclease I
: deoxyribonuclease IV
: type I site-specific deoxyribonuclease
: type II site-specific deoxyribonuclease
: type III site-specific deoxyribonuclease
: CC-preferring endodeoxyribonuclease
: deoxyribonuclease V
: T₄ deoxyribonuclease II
: T₄ deoxyribonuclease IV
: crossover junction endodeoxyribonuclease

EC 3.1.22: Endodeoxyribonucleases Producing 3'-Phosphomonoesters

: deoxyribonuclease II
: Aspergillus deoxyribonuclease K1
EC 3.1.22.3: now
: crossover junction endodeoxyribonuclease
: deoxyribonuclease X

EC 3.1.23: and EC 3.1.24 now EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5

Deleted sub-subclasses.

EC 3.1.25: Site-Specific Endodeoxyribonucleases Specific for Altered Bases

: deoxyribonuclease (pyrimidine dimer)
EC 3.1.25.2: Now, DNA- lyase

EC 3.1.26: Endoribonucleases Producing 5'-Phosphomonoesters

EC 3.1.27: Endoribonucleases Producing 3'-Phosphomonoesters

EC 3.1.27.1: Now, ribonuclease T₂, since the primary reaction is that of a lyase
EC 3.1.27.2: Now, Bacillus subtilis ribonuclease, since the reaction catalysed is that of a lyase
EC 3.1.27.3: Now, ribonuclease T₁, since the primary reaction is that of a lyase
EC 3.1.27.4: Now, ribonuclease U₂, since the primary reaction is that of a lyase
EC 3.1.27.5: Now, pancreatic ribonuclease.
EC 3.1.27.6: Now, Enterobacter ribonuclease, since the primary reaction is that of a lyase
: ribonuclease F
: ribonuclease V
EC 3.1.27.9: Now, tRNA-intron lyase
EC 3.1.27.10: Now, ribotoxin,

EC 3.1.30: Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 5'-Phosphomonoesters

EC 3.1.31: Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters

: micrococcal nuclease

EC 3.2: [Glycosylases]

EC 3.2.1: [Glycosidase]s, i.e. enzymes hydrolysing ''O''- and ''S''-glycosyl compounds

: α-amylase
: β-amylase
: glucan 1,4-α-glucosidase
: cellulase
: deleted
: endo-1,3(4)-β-glucanase
: inulinase
: endo-1,4-β-xylanase
: deleted
: oligo-1,6-glucosidase
: dextranase
: Now included with, cyclomaltodextrinase
: Now included with, cyclomaltodextrinase
: chitinase
: polygalacturonase
: deleted
: lysozyme
: exo-α-sialidase
: deleted
: α-glucosidase
: β-glucosidase
: α-galactosidase
: β-galactosidase
: α-mannosidase
: β-mannosidase
: β-fructofuranosidase
: deleted
: α,α-trehalase
: Now included with, β-N-acetylhexosaminidase
: Now included with, β-N-acetylhexosaminidase
: β-glucuronidase
: endo-1,3-β-xylanase
: amylo-α-1,6-glucosidase
: Now included with, hyaluronoglucosaminidase
: hyaluronoglucosaminidase
: hyaluronoglucuronidase
: xylan 1,4-β-xylosidase
: β-D-fucosidase
: glucan endo-1,3-β-D-glucosidase
: α-L-rhamnosidase
: pullulanase
: GDP-glucosidase
: β-L-rhamnosidase
: Now, endo-(13)-fucoidanase and, endo-(14)-fucoidanase
: glucosylceramidase
: galactosylceramidase
: Now known to be catalyzed by, α-galactosidase
: sucrose α-glucosidase
: α-N-acetylgalactosaminidase
: α-N-acetylglucosaminidase
: α-L-fucosidase
: β-N-acetylhexosaminidase
: β-N-acetylgalactosaminidase
: cyclomaltodextrinase
: non-reducing end α-L-arabinofuranosidase
: glucuronosyl-disulfoglucosamine glucuronidase
: isopullulanase
: glucan 1,3-β-glucosidase
: glucan endo-1,3-α-glucosidase
: glucan 1,4-α-maltotetraohydrolase
: mycodextranase
: glycosylceramidase
: 1,2-α-L-fucosidase
: 2,6-β-fructan 6-levanbiohydrolase
: levanase
: Deleted entry: The activity is covered by, α-L-rhamnosidase
: galacturan 1,4-α-galacturonidase
: isoamylase
: Now included with, pullulanase
: glucan 1,6-α-glucosidase
: glucan endo-1,2-β-glucosidase
: xylan 1,3-β-xylosidase
: licheninase
: glucan 1,4-β-glucosidase
: glucan endo-1,6-β-glucosidase
: L-iduronidase
: mannan 1,2-(1,3)-α-mannosidase
: mannan endo-1,4-β-mannosidase
: Now included with, non-reducing end α-L-arabinofuranosidase
: fructan β-fructosidase
: β-agarase
: exo-poly-α-digalacturonosidas
: κ-carrageenase
: glucan 1,3-α-glucosidase
: 6-phospho-β-galactosidase
: 6-phospho-β-glucosidase
: capsular-polysaccharide endo-1,3-α-galactosidase
: non-reducing end β-L-arabinopyranosidase
: arabinogalactan endo-β-1,4-galactanase
: Deleted, not sufficiently characterised.
: cellulose 1,4-β-cellobiosidase (non-reducing end)
: peptidoglycan β-N-acetylmuramidase
: α,α-phosphotrehalase
: glucan 1,6-α-isomaltosidase
: dextran 1,6-α-isomaltotriosidase
: mannosyl-glycoprotein endo-β-N-acetylglucosaminidase
: endo-α-N-acetylgalactosaminidase
: glucan 1,4-α-maltohexaosidase
: arabinan endo-1,5-α-L-arabinanase
: mannan 1,4-mannobiosidase
: mannan endo-1,6-α-mannosidase
: blood-group-substance endo-1,4-β-galactosidase
: keratan-sulfate endo-1,4-β-galactosidase
: steryl-β-glucosidase
: 3α(S)-strictosidine β-glucosidase
: mannosyl-oligosaccharide glucosidase
: protein-glucosylgalactosylhydroxylysine glucosidase
: lactase
: endogalactosaminidase
: identical to, endo-α-N-acetylgalactosaminidase
: 1,3-α-L-fucosidase
: 2-deoxyglucosidase
: mannosyl-oligosaccharide 1,2-α-mannosidase
: mannosyl-oligosaccharide 1,3-1,6-α-mannosidas
: branched-dextran exo-1,2-α-glucosidase
: glucan 1,4-α-maltotriohydrolase
: amygdalin β-glucosidase
: prunasin β-glucosidase
: vicianin β-glucosidase
: oligoxyloglucan β-glycosidase
: polymannuronate hydrolase
: maltose-6′-phosphate glucosidase
: endoglycosylceramidase
: 3-deoxy-2-octulosonidase
: raucaffricine β-glucosidase
: coniferin β-glucosidase
: 1,6-α-L-fucosidase
: glycyrrhizin hydrolase
: endo-α-sialidase
: glycoprotein endo-α-1,2-mannosidase
: xylan α-1,2-glucuronosidase
: chitosanase
: glucan 1,4-α-maltohydrolase
: difructose-anhydride synthase
: neopullulanase
: glucuronoarabinoxylan endo-1,4-β-xylanase
: mannan exo-1,2-1,6-α-mannosidase
EC 3.2.1.138: Now, anhydrosialidase
: α-glucuronidase
: lacto-N-biosidase
: 4-α-D-trehalose trehalohydrolase
: limit dextrinase
: poly(ADP-ribose) glycohydrolase
: 3-deoxyoctulosonase
: galactan 1,3-β-galactosidase
: β-galactofuranosidase
: thioglucosidase
EC 3.2.1.148: [The activity is most probably attributable to ((EnzExplorer|4.4.1.21)), S-ribosylhomocysteine lyase|The activity is most probably attributable to, S-ribosylhomocysteine lyase]
: β-primeverosidase
: oligoxyloglucan reducing-end-specific cellobiohydrolase
: xyloglucan-specific endo-β-1,4-glucanase
: mannosylglycoprotein endo-β-mannosidase
: fructan β-(2,1)-fructosidase
: fructan β-(2,6)-fructosidase
: xyloglucan-specific endo-processive β-1,4-glucanase
: oligosaccharide reducing-end xylanase
: ι-carrageenase
: α-agarase
: α-neoagaro-oligosaccharide hydrolase
EC 3.2.1.160: identical to, xyloglucan-specific exo-β-1,4-glucanase
: β-apiosyl-β-glucosidase
: λ-carrageenase
: 1,6-α-D-mannosidase
: galactan endo-1,6-β-galactosidase
: exo-1,4-β-D-glucosaminidase
: heparanase
: baicalin-β-D-glucuronidase
: hesperidin 6-O-α-L-rhamnosyl-β-D-glucosidase
: protein O-GlcNAcas
: mannosylglycerate hydrolase
: rhamnogalacturonan hydrolase
: unsaturated rhamnogalacturonyl hydrolase
: rhamnogalacturonan galacturonohydrolase
: rhamnogalacturonan rhamnohydrolase
: β-D-glucopyranosyl abscisate β-glucosidase
: cellulose 1,4-β-cellobiosidase (reducing end)
: α-D-xyloside xylohydrolase
: β-porphyranase
: gellan tetrasaccharide unsaturated glucuronyl hydrolase
: unsaturated chondroitin disaccharide hydrolase
: galactan endo-β-1,3-galactanase
: 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside β-D-glucosidase
: UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
: UDP-N,N′-diacetylbacillosamine 2-epimerase (hydrolysing)
: non-reducing end β-L-arabinofuranosidase
: protodioscin 26-O-β-D-glucosidase
: (Ara-f)3-Hyp β-L-arabinobiosidase
: avenacosidase *
: dioscin glycosidase (diosgenin-forming)
: dioscin glycosidase (3-O-β-D-Glc-diosgenin-forming)
: ginsenosidase type III
: ginsenoside Rb1 β-glucosidase
: ginsenosidase type I
: ginsenosidase type IV
: 20-O-multi-glycoside ginsenosidase
: limit dextrin α-1,6-maltotetraose-hydrolase
: β-1,2-mannosidase
: α-mannan endo-1,2-α-mannanase
: sulfoquinovosidase
: exo-chitinase (non-reducing end)
: exo-chitinase (reducing end)
: endo-chitodextinase
: carboxymethylcellulase
: 1,3-α-isomaltosidase
: isomaltose glucohydrolase
: oleuropein β-glucosidase
: mannosyl-oligosaccharide α-1,3-glucosidase
: glucosylglycerate hydrolase
: endoplasmic reticulum Man9GlcNAc2 1,2-α-mannosidase
: endoplasmic reticulum Man8GlcNAc2 1,2-α-mannosidase
: endo-(1→3)-fucoidanase
: endo-(1→4)-fucoidanase
: galactan exo-1,6-β-galactobiohydrolase (non-reducing end)
: exo β-1,2-glucooligosaccharide sophorohydrolase (non-reducing end)

EC 3.2.2: Hydrolysing ''N''-Glycosyl Compounds

: purine nucleosidase
: inosine nucleosidase
: uridine nucleosidase
: AMP nucleosidase
: NAD⁺ glycohydrolase
: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
: adenosine nucleosidase
: ribosylpyrimidine nucleosidase
: adenosylhomocysteine nucleosidase
: pyrimidine-5′-nucleotide nucleosidase
: β-aspartyl-N-acetylglucosaminidase
: inosinate nucleosidase
: 1-methyladenosine nucleosidase
: NMN nucleosidase
: DNA-deoxyinosine glycosylase
: methylthioadenosine nucleosidase
: deoxyribodipyrimidine endonucleosidase
EC 3.2.2.18: Now included with, peptide-N⁴-asparagine amidase
: ADP-ribosylarginine hydrolase
: DNA-3-methyladenine glycosylase I
: DNA-3-methyladenine glycosylase II, MAG1
: rRNA 'N-glycosylase
: DNA-formamidopyrimidine glycosylase
: ADP-ribosyl- hydrolase| ADP-ribosyl- hydrolase
: N-methyl nucleosidase
: futalosine hydrolase
: uracil-DNA glycosylase
: double-stranded uracil-DNA glycosylase
: thymine-DNA glycosylase
: aminodeoxyfutalosine nucleosidase
: adenine glycosylase

EC 3.2.3: Hydrolysing ''S''-Glycosyl Compounds

Deleted sub-subclass

EC 3.3: Acting on Ether Bonds

EC 3.3.1: Thioether and trialkylsulfonium hydrolases

: adenosylhomocysteinase
: S-adenosyl-L-methionine hydrolase (L-homoserine-forming)
EC 3.3.1.3: [The activity is most probably attributable to ((EnzExplorer|4.4.1.21)), S-ribosylhomocysteine lyase|The activity is most probably attributable to, S-ribosylhomocysteine lyase]

EC 3.3.2: Ether Hydrolases

: isochorismatase
: alkenylglycerophosphocholine hydrolase
EC 3.3.2.3: Now known to comprise two enzymes, microsomal epoxide hydrolase and soluble epoxide hydrolase
: trans-epoxysuccinate hydrolase
EC 3.3.2.5: Now included in, lysoplasmalogenase
: leukotriene-A₄ hydrolase
: hepoxilin-epoxide hydrolase
: limonene-1,2-epoxide hydrolase
: microsomal epoxide hydrolase
: soluble epoxide hydrolase
: cholesterol-5,6-oxide hydrolase
: oxepin-CoA hydrolase
: chorismatase
: 2,4-dinitroanisole O-demethylase
: trans-2,3-dihydro-3-hydroxyanthranilic acid synthase

EC 3.4: Acting on [peptide bond]s – [Peptidase]

EC 3.4.1 α-amino acyl peptide hydrolases (discontinued)

EC 3.4.1.1: Now, leucyl aminopeptidase
EC 3.4.1.2: Now, membrane alanyl aminopeptidase
EC 3.4.1.3: Now, tripeptide aminopeptidase
EC 3.4.1.4: Now, prolyl aminopeptidase

EC 3.4.2 Peptidyl amino acid hydrolases (discontinued)

EC 3.4.2.1: Now, carboxypeptidase A
EC 3.4.2.2: Now, carboxypeptidase B
EC 3.4.2.3: Now, Gly-Xaa carboxypeptidase

EC 3.4.3: Dipeptide hydrolases (deleted sub-subclass)

EC 3.4.3.1: Now, cytosol nonspecific dipeptidase
EC 3.4.3.2: Now, cytosol nonspecific dipeptidase
EC 3.4.3.3: Now, Xaa-His dipeptidase
EC 3.4.3.4: Now, Xaa-methyl-His dipeptidase
EC 3.4.3.5: Now, membrane alanyl aminopeptidase
EC 3.4.3.6: Now, cytosol nonspecific dipeptidase
EC 3.4.3.7: Now, Xaa-Pro dipeptidase

EC 3.4.4 Peptidyl Peptide Hydrolases (discontinued)

EC 3.4.4.1: Now, pepsin A
EC 3.4.4.2: Now, pepsin B
EC 3.4.4.3: Now, chymosin
EC 3.4.4.4: Now, trypsin
EC 3.4.4.5: Now, chymotrypsin
EC 3.4.4.6: Now, chymotrypsin
EC 3.4.4.7: Now covered by, pancreatic elastase and, leukocyte elastase
EC 3.4.4.8: Now, enteropeptidase
EC 3.4.4.9: Now, dipeptidyl-peptidase I
EC 3.4.4.10: Now, papain
EC 3.4.4.11: Now, chymopapain
EC 3.4.4.12: Now, ficain
EC 3.4.4.13: Now, thrombin
EC 3.4.4.14: Now, plasmin
EC 3.4.4.15: Now, renin
EC 3.4.4.16: Now covered by the microbial serine proteinases,,,, and
EC 3.4.4.17: Now covered by the microbial aspartic proteinases,,,,,,,,, and
EC 3.4.4.18: Now, streptopain
EC 3.4.4.19: Now, microbial collagenase
EC 3.4.4.20: Now, clostripain
EC 3.4.4.21: Now and
EC 3.4.4.22: Now, gastricsin
EC 3.4.4.23: Now, cathepsin D
EC 3.4.4.24: Now covered by and
EC 3.4.4.25: deleted

EC 3.4.11 [Aminopeptidase]s

: leucyl aminopeptidase
: membrane alanyl aminopeptidase
: cystinyl aminopeptidase
: tripeptide aminopeptidase
: prolyl aminopeptidase
: aminopeptidase B
: glutamyl aminopeptidase
EC 3.4.11.8: Now EC 3.4.19.3, pyroglutamyl-peptidase I
: Xaa-Pro aminopeptidase
: bacterial leucyl aminopeptidase
EC 3.4.11.11: Deleted
EC 3.4.11.12: Deleted
: Clostridial aminopeptidase
: cytosol alanyl aminopeptidase
: aminopeptidase Y
: Xaa-Trp aminopeptidase
: tryptophanyl aminopeptidase
: methionyl aminopeptidase
: D-stereospecific aminopeptidase
: aminopeptidase Ey
: aspartyl aminopeptidase
: aminopeptidase I
: PepB aminopeptidase
: aminopeptidase S
: β-peptidyl aminopeptidase
: intermediate cleaving peptidase 55

EC 3.4.12 Peptidylamino-acid hydrolases or acylamino-acid hydrolases (deleted sub-subclass)

EC 3.4.12.1: Now and
EC 3.4.12.2: Now, carboxypeptidase A
EC 3.4.12.3: Now, carboxypeptidase B
EC 3.4.12.4: Now, lysosomal Pro-Xaa carboxypeptidase
EC 3.4.12.5: Now, N-acetylmuramoyl-L-alanine amidase
EC 3.4.12.6: Now, muramoyl-pentapeptidase carboxypeptidase
EC 3.4.12.7: Now, lysine carboxypeptidase
EC 3.4.12.8: Now, Gly-Xaa carboxypeptidase
EC 3.4.12.9: aspartate carboxypeptidase
EC 3.4.12.10: Now, γ-glutamyl hydrolase
EC 3.4.12.11: Now, alanine carboxypeptidase
EC 3.4.12.12: Now and
EC 3.4.12.13: γ-glutamylglutamate carboxypeptidase

EC 3.4.13 Dipeptidases

EC 3.4.13.1: Now, cytosol nonspecific dipeptidase
EC 3.4.13.2: Now, cytosol nonspecific dipeptidase
EC 3.4.13.3: The activity is covered by, cytosol nonspecific dipeptidase and, β-Ala-His dipeptidase
: Xaa-Arg dipeptidase
: Xaa-methyl-His dipeptidase
EC 3.4.13.6: Now, membrane alanyl aminopeptidase
: Glu-Glu dipeptidase
EC 3.4.13.8: Now, cytosol nonspecific dipeptidase
: Xaa-Pro dipeptidase
EC 3.4.13.10: Now, β-aspartyl-peptidase
EC 3.4.13.11: Now, membrane dipeptidase
: Met-Xaa dipeptidase
EC 3.4.13.13: Now, Xaa-His dipeptidase
EC 3.4.13.14: Deleted
EC 3.4.13.15: Now, cytosol nonspecific dipeptidase
: Deleted
: non-stereospecific dipeptidase
: cytosol nonspecific dipeptidase
: membrane dipeptidase
: β-Ala-His dipeptidase
: dipeptidase E
: D-Ala-D-Ala dipeptidase
: cysteinylglycine-S-conjugate dipeptidase

EC 3.4.14 [Dipeptidyl peptidase]s and [tripeptidyl peptidase]s

: dipeptidyl-peptidase I
: dipeptidyl-peptidase II
EC 3.4.14.3: Now, acylaminoacyl-peptidase
: dipeptidyl-peptidase III
: dipeptidyl-peptidase IV
: dipeptidyl-dipeptidase
EC 3.4.14.7: Deleted
EC 3.4.14.8: Now, tripeptidyl-peptidase II
: tripeptidyl-peptidase I
: tripeptidyl-peptidase II
: Xaa-Pro dipeptidyl-peptidase
: Xaa-Xaa-Pro tripeptidyl-peptidase
: γ-D-glutamyl-Llysine dipeptidyl-peptidase
: peptidase| peptidase

EC 3.4.15 [Peptidyl dipeptidase]s

: peptidyl-dipeptidase A
EC 3.4.15.2: Now, peptidyl-glycinamidase
EC 3.4.15.3: Now, peptidyl-dipeptidase Dcp
: Peptidyl-dipeptidase B
: Peptidyl-dipeptidase Dcp
: cyanophycinase

EC 3.4.16 [Serine type carboxypeptidase]s

EC 3.4.16.1: Transferred entry: serine carboxypeptidase. Now, carboxypeptidase D
: lysosomal Pro-Xaa carboxypeptidase
EC 3.4.16.3: Now included with, carboxypeptidase C
: serine-type D-Ala-D-Ala carboxypeptidase
: carboxypeptidase C
: carboxypeptidase D

EC 3.4.17 [Metallocarboxypeptidase]s

: carboxypeptidase A
: carboxypeptidase B
: lysine carboxypeptidase
: Gly-Xaa carboxypeptidase
EC 3.4.17.5: Deleted
: alanine carboxypeptidase
EC 3.4.17.7: Now, N-acetylmuramoyl-L-alanine amidase
: muramoylpentapeptide carboxypeptidase
EC 3.4.17.9: Now included with, Gly-Xaa carboxypeptidase
: carboxypeptidase E
: glutamate carboxypeptidase
: carboxypeptidase M
: Muramoyltetrapeptide carboxypeptidase
: zinc D-Ala-D-Ala carboxypeptidase
: carboxypeptidase A₂
: membrane Pro-Xaa carboxypeptidase
: tubulinyl-Tyr carboxypeptidase
: carboxypeptidase T
: Carboxypeptidase Taq
: carboxypeptidase U
: Glutamate carboxypeptidase II
: metallocarboxypeptidase D
: angiotensin-converting enzyme 2
: tubulin-glutamate carboxypeptidase

EC 3.4.18 [Cysteine type carboxypeptidase]s

: cathepsin X

EC 3.4.19 [Omega peptidase]s

: acylaminoacyl-peptidase
: peptidyl-glycinamidase
: pyroglutamyl-peptidase I
EC 3.4.19.4: Deleted
: β-aspartyl-peptidase
: pyroglutamyl-peptidase II
: N-formylmethionyl-peptidase
EC 3.4.19.8: now, glutamate carboxypeptidase II
: folate γ-glutamyl hydrolase
EC 3.4.19.10: Now, N-acetylmuramoyl-L-alanine amidase
: γ-Dglutamyl-meso-diaminopimelate peptidase
: ubiquitinyl hydrolase 1
: glutathione γ-glutamate hydrolase
: leukotriene-C₄ hydrolase
: desampylase
: glucosinolate γ-glutamyl hydrolase

EC 3.4.21: [Serine protease]s

: chymotrypsin
: chymotrypsin C
: metridin
: trypsin
: thrombin
: coagulation factor Xa
: plasmin
EC 3.4.21.8: Now and
: enteropeptidase
: acrosin
EC 3.4.21.11: Now, leukocyte elastase
: α-lytic endopeptidase
EC 3.4.21.13: Now, carboxypeptidase D
EC 3.4.21.14: now, endopeptidase So
EC 3.4.21.15: Now, oryzin
EC 3.4.21.16: Deleted
EC 3.4.21.17: Deleted
EC 3.4.21.18: Deleted
: glutamyl endopeptidase
: cathepsin G
: coagulation factor VIIa
: coagulation factor IXa
EC 3.4.21.23: Deleted
EC 3.4.21.24: Deleted
: cucumisin
: prolyl oligopeptidase
: coagulation factor XIa
EC 3.4.21.28: Now, venombin A
EC 3.4.21.29: Now, venombin A
EC 3.4.21.30: Now, venombin A
EC 3.4.21.31: Now, u-plasminogen activator
: brachyurin
EC 3.4.21.33: Deleted
: plasma kallikrein
: tissue kallikrein
: pancreatic elastase
: leukocyte elastase
: coagulation factor XIIa
: chymase
EC 3.4.21.40: Deleted
: Complement subcomponent C^1r
: complement subcomponent C^1s
: classical-complement-pathway C3/C5 convertase
EC 3.4.21.44: Now, classical-complement-pathway C3/C5 convertase
: complement factor I
: complement factor D
: alternative-complement-pathway C3/C5 convertase
: cerevisin
: hypodermin C
: lysyl endopeptidase
EC 3.4.21.51: Deleted
EC 3.4.21.52: Deleted
: edopeptidase La
: γ-renin
: venombin AB
EC 3.4.21.56: Now considered to be, cucumisin
: leucyl endopeptidase
EC 3.4.21.58: Deleted
: tryptase
: scutelarin
: kexin
: subtilisin
: oryzin
: endopeptidase K
: thermomycolin
: thermitase
: endopeptidase So
: t-plasminogen activator
: protein C (activated)
: pancreatic endopeptidase E
: pancreatic elastase II
: IgA-specific serine endopeptidase
: u-plasminogen activator
: venombin A
: furin
: myeloblastin
: semenogelase
: granzyme A
: granzyme B
: streptogrisin A
: streptogrisin B
: glutamyl endopeptidase II
: oligopeptidase B
: limulus clotting factor C
: limulus clotting factor B
: limulus clotting enzyme
EC 3.4.21.87: Now, omptin
: repressor LexA
: signal peptidase I
: togavirin
: flavivirin
: endopeptidase Clp
: proprotein convertase 1
: proprotein convertase 2
: snake venom factor V activator
: lactocepin
: assemblin
: hepacivirin
: spermosin
: sedolisin
: xanthomonalisin
: C-terminal processing peptidase
: physarolisin
: mannan-binding lectin-associated serine protease-2
: rhomboid protease
: hepsin
: peptidase Do
: HtrA2 peptidase
: matriptase
: C5a peptidase
: aqualysin 1
: site-1 protease
: pestivirus NS3 polyprotein peptidase
: equine arterivirus serine peptidase
: infectious pancreatic necrosis birnavirus Vp4 peptidase
: SpoIVB peptidase
: stratum corneum chymotryptic enzyme
: kallikrein 8
: kallikrein 13
: oviductin
: Lys-Lys/Arg-Xaa endopeptidase

EC 3.4.22 [Cysteine protease]s

: cathepsin B
: papain
: ficain
EC 3.4.22.4: Now and
EC 3.4.22.5: Now and
: chymopapain
: asclepain
: clostripain
EC 3.4.22.9: Now, cerevisin
: streptopain
EC 3.4.22.11: Now, insulysin
EC 3.4.22.12: Now, γ-glutamyl hydrolase
EC 3.4.22.13: Deleted
: actinidain
: cathepsin L
: cathepsin H
EC 3.4.22.17: Now, calpain-2
EC 3.4.22.18: Now, prolyl oligopeptidase
EC 3.4.22.19: Now, thimet oligopeptidase
EC 3.4.22.20: Deleted
EC 3.4.22.21: Now, proteasome endopeptidase complex
EC 3.4.22.22: Now, saccharolysin
EC 3.4.22.23: Now, kexin
: Cathepsin T
: Glycyl endopeptidase
: Cancer procoagulant
: cathepsin S
: picornain 3C
: picornain 2A
: Caricain
: Ananain
: Stem bromelain
: Fruit bromelain
: Legumain
: Histolysain
: caspase-1
: Gingipain R
: Cathepsin K
: adenain
: bleomycin hydrolase
: cathepsin F
: cathepsin O
: cathepsin V
: nuclear-inclusion-a endopeptidase
: helper-component proteinase
: L-peptidase
: gingipain K
: staphopain
: separase
: V-cath endopeptidase
: cruzipain
: calpain-1
: calpain-2
: calpain-3
: caspase-2
: caspase-3
: caspase-4
: caspase-5
: caspase-6
: caspase-7
: caspase-8
: caspase-9
: caspase-10
: caspase-11
: peptidase 1 (mite)
: calicivirin
: zingipain
: Ulp1 peptidase
: SARS coronavirus main proteinase
: sortase A
: sortase B

EC 3.4.23 [Aspartic endopeptidase]s

: pepsin A
: pepsin B
: gastricsin
: chymosin
: cathepsin D
EC 3.4.23.6: Now, pycnoporopepsin
EC 3.4.23.7: Now, penicillopepsin
EC 3.4.23.8: Now, saccharopepsin
EC 3.4.23.9: Now, rhizopuspepsin
EC 3.4.23.10: Now, endothiapepsin
EC 3.4.23.11: Deleted entry
: nepenthesin
EC 3.4.23.13: Deleted
EC 3.4.23.14: Deleted
: renin
: HIV-1 retropepsin
: pro-opiomelanocortin converting enzyme
: aspergillopepsin I
: aspergillopepsin II
: penicillopepsin
: rhizopuspepsin
: endothiapepsin
: mucorpepsin
: candidapepsin
: saccharopepsin
: rhodotorulapepsin
EC 3.4.23.27: Now, physarolisin
: acrocylindropepsin
: polyporopepsin
: pycnoporopepsin
: scytalidopepsin A
: scytalidopepsin B
EC 3.4.23.33: Now, xanthomonalisin
: cathepsin E
: barrierpepsin
: signal peptidase II
EC 3.4.23.37: Now, pseudomonalisin
: plasmepsin I
: plasmepsin II
: phytepsin
: yapsin 1
: thermopsin
: prepilin peptidase
: nodavirus endopeptidase
: memapsin 1
: memapsin 2
: HIV-2 retropepsin
: plasminogen activator Pla
: omptin
: human endogenous retrovirus K endopeptidase
: HycI peptidase
: preflagellin peptidase

EC 3.4.24: [Metallopeptidase]s

: atrolysin A
: Deleted entry: Sepia proteinase
: microbial collagenase
: now serralysin
EC 3.4.24.5: Deleted entry: lens neutral proteinase. Now included with and
: leucolysin
: interstitial collagenase
EC 3.4.24.8: Transferred entry: Achromobacter iophagus collagenase. Now, microbial collagenase
EC 3.4.24.9: Deleted entry: Trichophyton schoenleinii collagenase
EC 3.4.24.10: Deleted entry: Trichophyton mentagrophytes keratinase
: neprilysin
: envelysin
: IgA-specific metalloendopeptidase
: procollagen N-endopeptidase
: thimet oligopeptidase
: neurolysin
: stromelysin 1
: meprin A
: procollagen C-endopeptidase
: peptidyl-Lys metalloendopeptidase
: astacin
: stromelysin 2
: matrilysin
: gelatinase a
: vibriolysin
: pseudolysin
: thermolysin
: bacillolysin
: aureolysin
: coccolysin
: mycolysin
: β-lytic metalloendopeptidase
: peptidyl-Asp metalloendopeptidase
: neutrophil collagenase
: gelatinase B
: leishmanolysin
: saccharolysin
: gametolysin
: deuterolysin
: serralysin
: atrolysin B
: atrolysin C
: atroxase
: atrolysin E
: atrolysin F
: adamalysin
: horrilysin
: ruberlysin
: bothropasin
: bothrolysin
: ophiolysin
: trimerelysin I
: trimerelysin II
: mucrolysin
: pitrilysin
: insulysin
: O-sialoglycoprotein endopeptidase
: russellysin
: mitochondrial intermediate peptidase
: dactylysin
: nardilysin
: magnolysin
: meprin B
: mitochondrial processing peptidase
: macrophage elastase
: choriolysin L
: choriolysin H
: tentoxilysin
: bontoxilysin
: oligopeptidase A
: endothelin-converting enzyme 1
: fibrolase
: jararhagin
: fragilysin
: lysostaphin
: flavastacin
: snapalysin
: gpr endopeptidase
: pappalysin-1
: membrane-type matrix metalloproteinase-1
: ADAM10 endopeptidase
: ADAMTS-4 endopeptidase
: anthrax lethal factor endopeptidase
: Ste24 endopeptidase
: S2P endopeptidase
: ADAM 17 endopeptidase
: ADAMTS13 endopeptidase

EC 3.4.25 [Threonine endopeptidase]s

: proteasome endopeptidase complex
: HslU—HslV peptidase
EC 3.4.99.7: Deleted entry: euphorbain
EC 3.4.99.8: Deleted entry: Gliocladium proteinase
EC 3.4.99.9: Deleted entry: hurain. Now considered to be, cucumisin
EC 3.4.99.10: Transferred entry: insulinase. Now, insulysin
EC 3.4.99.11: Deleted entry: Streptomyces alkalophilic keratinase
EC 3.4.99.12: Deleted entry: Trichophyton mentagrophytes keratinase
EC 3.4.99.13: Transferred entry: β-lytic proteinase. Now, β-lytic metalloendopeptidase
EC 3.4.99.14: Deleted entry: mexicanain
EC 3.4.99.15: Deleted entry: Paecilomyces proteinase
EC 3.4.99.16: Deleted entry: Penicillium notatum extracellular proteinase
EC 3.4.99.17: Deleted entry: peptidoglycan endopeptidase
EC 3.4.99.18: Deleted entry: pinguinain
EC 3.4.99.19: Transferred entry: renin. Now, renin
EC 3.4.99.20: Deleted entry: scopulariopsis proteinase
EC 3.4.99.21: Deleted entry: solanain. Now considered, cucumisin
EC 3.4.99.22: Transferred entry: staphylokinase., aureolysin
EC 3.4.99.23: Deleted entry: tabernamontanain. Now considered EC 3.4.21.25, cucumisin
EC 3.4.99.24: Deleted entry: Tenebrio α-proteinase
EC 3.4.99.25: Transferred entry: trametes acid proteinase., rhizopuspepsin
EC 3.4.99.26: Transferred entry: urokinase. Now, t-plasminogen activator
EC 3.4.99.27: Deleted entry: Echis carinatus prothrombin-activating proteinase
EC 3.4.99.28: Transferred entry: Oxyuranus scutellatus prothrombin-activating proteinase., scutelarin
EC 3.4.99.29: Deleted entry: Myxobacter AL-1 proteinase I
EC 3.4.99.30: Transferred entry: Myxobacter AL-1 proteinase II., peptidyl-Lys metalloendopeptidase
EC 3.4.99.31: Transferred entry: tissue endopeptidase degrading collagenase synthetic substrate., thimet oligopeptidase
EC 3.4.99.32: Transferred entry: Armillaria mellea neutral proteinase. Now, peptidyl-Lys metalloendopeptidase
EC 3.4.99.33: Deleted entry: cathepsin R
EC 3.4.99.34: Deleted entry: mytilidase
EC 3.4.99.35: Transferred entry: premurein-leader peptidase. Now, signal peptidase II
EC 3.4.99.36: Transferred entry: leader peptidase. Now, signal peptidase I
EC 3.4.99.37: Deleted entry: RecA peptidase
EC 3.4.99.38: Transferred entry: pro-opiomelanotropin-converting proteinase. Now, pro-opiomelanocortin converting enzyme
EC 3.4.99.39: Deleted entry: pseudomurein endopeptidase
EC 3.4.99.40: Deleted entry: pro-gonadoliberin proteinase
EC 3.4.99.41: Transferred entry: mitochondrial processing peptidase. Now, mitochondrial processing peptidase
EC 3.4.99.42: Deleted entry: leucyllysine endopeptidase
EC 3.4.99.43: Transferred entry: thermopsin. Npw, thermopsin
EC 3.4.99.44: Transferred entry: pitrilysin. Now, pitrilysin
EC 3.4.99.45: Transferred entry: insulinase. Now, insulysin
EC 3.4.99.46: Transferred entry: multicatalytic endopeptidase complex. Now, proteasome endopeptidase complex

EC 3.5: Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.1: In linear amides

: asparaginase
: glutaminase
: ω-amidase
: amidase
: urease
: β-ureidopropionase
: ureidosuccinase
: formylaspartate deformylase
: arylformamidase
: formyltetrahydrofolate deformylase
: penicillin amidase
: biotinidase
: aryl-acylamidase
: N-acyl-aliphatic-L-amino acid amidohydrolase
: aspartoacylase
: acetylornithine deacetylase
: acyl-lysine deacylase
: succinyl-diaminopimelate desuccinylase
: nicotinamidase
: citrullinase
: N-acetyl-β-alanine deacetylas
: pantothenase
: ceramidase
: choloylglycine hydrolase
: N-acetylglucosamine-6-phosphate deacetylase
: N⁴-(β-N-acetylglucosaminyl)-L-asparaginase
EC 3.5.1.27: The activity is covered by, peptide deformylase
: N-acetylmuramoyl-L-alanine amidase
: 2-(acetamidomethylene)succinate hydrolase
: 5-aminopentanamidase
: formylmethionine deformylase
: hippurate hydrolase
: N-acetylglucosamine deacetylase
EC 3.5.1.34: [Identical with ((EnzExplorer|3.4.13.5)), Xaa-methyl-His dipeptidase|Identical with, Xaa-methyl-His dipeptidase]
: D-glutaminase
: N-methyl-2-oxoglutaramate hydrolase
EC 3.5.1.37: [Delete, identical with ((EnzExplorer|3.5.1.26)) N(4)-(β-N-acetylglucosaminyl)-L-asparaginase|Delete, identical with N⁴-(β-N-acetylglucosaminyl)-L-asparaginase]
: glutamin-(asparagin-)ase
: alkylamidase
: acylagmatine amidase
: chitin deacetylase
: nicotinamide-nucleotide amidase
: peptidyl-glutaminase
: protein-glutamine glutaminase
EC 3.5.1.45: Now listed only as urea carboxylase
: 6-aminohexanoate-dimer hydrolase
: N-acetyldiaminopimelate deacetylase
: acetylspermidine deacetylase
: formamidase
: pentanamidase
: 4-acetamidobutyryl-CoA deacetylase
: peptide-N⁴-(N-acetyl-β-glucosaminyl)asparagine amidase
: N-carbamoylputrescine amidase
: allophanate hydrolase
: long-chain-fatty-acyl-glutamate deacylase
: N,N-dimethylformamidase
: tryptophanamidase
: N-benzyloxycarbonylglycine hydrolase
: N-carbamoylsarcosine amidase
: N-(long-chain-acyl)ethanolamine deacylase
: mimosinase
: acetylputrescine deacetylase
: 4-acetamidobutyrate deacetylase
: N^α-benzyloxycarbonylleucine hydrolase
: theanine hydrolase
: 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase
: 4-methyleneglutaminase
: N-formylglutamate deformylase
: glycosphingolipid deacylase
: aculeacin-A deacylase
: N-feruloylglycine deacylase
: D-benzoylarginine-4-nitroanilide amidase
: carnitinamidase
: chenodeoxycholoyltaurine hydrolase
: urethanase
: arylalkyl acylamidase
: N-carbamoyl-D-amino-acid hydrolase
: glutathionylspermidine amidase
: phthalyl amidase
EC 3.5.1.80: Identical to, N-acetylglucosamine-6-phosphate deacetylase
: N-acyl-D-amino-acid deacylase
: N-acyl-D-glutamate deacylase
: N-acyl-D-aspartate deacylase
: biuret amidohydrolase
: (S)-N-acetyl-1-phenylethylamine hydrolase
: mandelamide amidase
: N-carbamoyl-L-amino-acid hydrolase
: peptide deformylase
: N-acetylglucosaminylphosphatidylinositol deacetylase
: adenosylcobinamide hydrolase
: N-substituted formamide deformylase
: pantetheine hydrolase
: glutaryl-7-aminocephalosporanic-acid acylase
: γ-glutamyl-γ-aminobutyrate hydrolase
: N-malonylurea hydrolase
: succinylglutamate desuccinylase
: acyl-homoserine-lactone acylase
: histone deacetylase
: fatty acid amide hydrolase
: (R)-amidase
: L-proline amide hydrolase
: 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5′-monophosphate deformylase
: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-α-D-glucopyranoside deacetylase
: peptidoglycan-N-acetylglucosamine deacetylase
: chitin disaccharide deacetylase
: N-formylmaleamate deformylase
: maleamate amidohydrolase
: UDP-3-O-acyl-N-acetylglucosamine deacetylase
: sphingomyelin deacylase
: ureidoacrylate amidohydrolase
: 2-oxoglutaramate amidase
: 2′-N-acetylparomamine deacetylase
: 2′′′-acetyl-6′′′-hydroxyneomycin C deacetylase
: N-acyl-aromatic-L-amino acid amidohydrolase
: mycothiol S-conjugate amidase
: ureidoglycolate amidohydrolase
: 6-aminohexanoate-oligomer endohydrolase
: γ-glutamyl hercynylcysteine S-oxide hydrolase
: Pup amidohydrolase
EC 3.5.1.120: Now, 2-aminomuconate deaminase
: protein N-terminal asparagine amidohydrolase
: protein N-terminal glutamine amidohydrolase
: γ-glutamylanilide hydrolase
: protein deglycase
: N²-acetyl-L-2,4-diaminobutanoate deacetylase
: oxamate amidohydrolase
: jasmonoyl-L-amino acid hydrolase
: deaminated glutathione amidase
: N⁵-(cytidine 5′-diphosphoramidyl)-L-glutamine hydrolase
: -lysine hydrolase|-lysine hydrolase
: 1-carboxybiuret hydrolase
: -ornithine hydrolase|-ornithine hydrolase
: N^α-acyl-L-glutamine aminoacylase
: (indol-3-yl)acetyl-L-aspartate hydrolase
: N⁴-acetylcytidine amidohydrolase
: N,N′-diacetylchitobiose non-reducing end deacetylase

3.5.2: In cyclic amides

: barbiturase
: dihydropyrimidinase
: dihydroorotase
: carboxymethylhydantoinase
: allantoinase
: β-lactamase
: imidazolonepropionase
EC 3.5.2.8: Now included with, β-lactamase
: 5-oxoprolinase (ATP-hydrolysing)
: creatininase
: L-lysine-lactamase
: 6-aminohexanoate-cyclic-dimer hydrolase
: 2,5-dioxopiperazine hydrolase
: N-methylhydantoinase (ATP-hydrolysing)
: cyanuric acid amidohydrolase
: maleimide hydrolase
: hydroxyisourate hydrolase
: enamidase
: streptothricin hydrolase
: isatin hydrolase

3.5.3: In linear amidines

: arginase
: guanidinoacetase
: creatinase
: allantoicase
: formimidoylaspartate deiminase
: arginine deiminase
: guanidinobutyrase
: formimidoylglutamase
: allantoate deiminase
: D-arginase
: agmatinase
: agmatine deiminase
: formimidoylglutamate deiminase
: amidinoaspartase
: protein-arginine deiminase
: methylguanidinase
: guanidinopropionase
: dimethylargininase
EC 3.5.3.19: Now, ureidoglycolate amidohydrolase
: diguanidinobutanase
: Methylenediurea deaminase
: proclavaminate amidinohydrolase
: N-succinylarginine dihydrolase
: N¹-aminopropylagmatine ureohydrolase
: N^ω-hydroxy-L-arginine amidinohydrolase
: (S)-ureidoglycine aminohydrolase

3.5.4: In cyclic amidines

: cytosine deaminase
: adenine deaminase
: guanine deaminase
: adenosine deaminase
: cytidine deaminase
: AMP deaminase
: ADP deaminase
: aminoimidazolase
: methenyltetrahydrofolate cyclohydrolase
: IMP cyclohydrolase
: pterin deaminase
: dCMP deaminase
: dCTP deaminase
EC 3.5.4.14: Now included in, cytidine deaminase
: guanosine deaminase
: GTP cyclohydrolase I
: adenosine-phosphate deaminase
: ATP deaminase
: phosphoribosyl-AMP cyclohydrolase
: pyrithiamine deaminase
: creatinine deaminase
: 1-pyrroline-4-hydroxy-2-carboxylate deaminase
: blasticidin-S deaminase
: sepiapterin deaminase
: GTP cyclohydrolase II
: diaminohydroxyphosphoribosylaminopyrimidine deaminase
: methenyltetrahydromethanopterin cyclohydrolase
: S-adenosylhomocysteine deaminase
: GTP cyclohydrolase IIa
: dCTP deaminase (dUMP-forming)
: S-methyl-5′-thioadenosine deaminase
: 8-oxoguanine deaminase
: tRNA(adenine³⁴) deaminase
: tRNA^Ala(adenine³⁷) deaminase
: tRNA(cytosine⁸) deaminase
: mRNA(cytosine⁶⁶⁶⁶) deaminase
: double-stranded RNA adenine deaminase
: single-stranded DNA cytosine deaminase
: GTP cyclohydrolase IV
: aminodeoxyfutalosine deaminase
: 5'-deoxyadenosine deaminase
: N-isopropylammelide isopropylaminohydrolase
: hydroxydechloroatrazine ethylaminohydrolase
: ectoine hydrolase
: melamine deaminase
: cAMP deaminase

3.5.5: In nitriles

3.5.99: In other compounds

: riboflavinase
: aminopyrimidine aminohydrolase
EC 3.5.99.3: Now, hydroxydechloroatrazine ethylaminohydrolase
EC 3.5.99.4: Now, N-isopropylammelide isopropylaminohydrolase
: 2-aminomuconate deaminase
: glucosamine-6-phosphate deaminase
: 1-aminocyclopropane-1-carboxylate deaminase
: 5-nitroanthranilic acid aminohydrolase
: 2-nitroimidazole nitrohydrolase
: 2-iminobutanoate/2-iminopropanoate deaminase
: 2-aminomuconate deaminase (2-hydroxymuconate-forming)

EC 3.6: Acting on">Acid anhydride hydrolases">Acting on [acid anhydride]s

3.6.1: In phosphorus-containing anhydrides

: inorganic diphosphatase
: trimetaphosphatase
: adenosinetriphosphatase
EC 3.6.1.4: Now included with, adenosinetriphosphatase
: apyrase
: nucleoside diphosphate phosphatase
: acylphosphatase
: ATP diphosphatase
: nucleotide diphosphatase
: endopolyphosphatase
: exopolyphosphatase
: dCTP diphosphatase
: ADP-ribose diphosphatase
: adenosine-tetraphosphatase
: nucleoside-triphosphatase
: CDP-glycerol diphosphatase
: bis(5′-nucleosyl)-tetraphosphatase (asymmetrical))
: FAD diphosphatase
EC 3.6.1.19: Now, nucleotide diphosphatase
: 5′-acylphosphoadenosine hydrolase
: ADP-sugar diphosphatase
: NAD⁺ diphosphatase
: dUTP diphosphatase
: nucleoside phosphoacylhydrolase
: triphosphatase
: CDP-diacylglycerol diphosphatase
: undecaprenyl-diphosphatase
: thiamine-triphosphatase
: bis(5′-adenosyl)-triphosphatase
EC 3.6.1.30: Now covered by and .
: phosphoribosyl-ATP diphosphatase
EC 3.6.1.32: Now, myosin ATPase
EC 3.6.1.33: Now, dynein ATPase
EC 3.6.1.34: Transferred entry: H⁺-transporting ATP synthase. Now, H⁺-transporting two-sector ATPase
EC 3.6.1.35: Now, H⁺-exporting ATPase
EC 3.6.1.36: Now, H⁺/K⁺-exchanging ATPase
EC 3.6.1.37: Now, Na⁺/K⁺-exchanging ATPase
EC 3.6.1.38: Now, Ca²⁺-transporting ATPase
: thymidine-triphosphatase
: guanosine-5′-triphosphate,3′-diphosphate phosphatase
: bis(5′-nucleosyl)-tetraphosphatase (symmetrical)
: guanosine-diphosphatase
: dolichyldiphosphatase
: oligosaccharide-diphosphodolichol diphosphatase
: UDP-sugar diphosphatase
EC 3.6.1.46: Now, heterotrimeric G-protein GTPase
EC 3.6.1.47: Now, protein-synthesizing GTPase
EC 3.6.1.49: Now, signal-recognition-particle GTPase
EC 3.6.1.50: Now, dynamin GTPase
EC 3.6.1.51: Now, tubulin GTPase
: diphosphoinositol-polyphosphate diphosphatase
: Mn²⁺-dependent ADP-ribose/CDP-alcohol diphosphatase
: UDP-2,3-diacylglucosamine diphosphatase
: 8-oxo-dGTP diphosphatase
: 2-hydroxy-dATP diphosphatase
: UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose hydrolase
: 8-oxo-dGDP phosphatase
: m7GpppX diphosphatase|5′-- diphosphatase
: diadenosine hexaphosphate hydrolase (AMP-forming)
: diadenosine hexaphosphate hydrolase (ATP-forming)
: m7GpppN-mRNA hydrolase|5′-- hydrolase
: α-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase
: inosine diphosphate phosphatase
: (d)CTP diphosphatase
: XTP/dITP diphosphatase
: dihydroneopterin triphosphate diphosphatase
: geranyl diphosphate phosphohydrolase
: 8-oxo-(d)GTP phosphatase
: guanosine-5′-diphospho-5′- diphosphatase|guanosine-5′-diphospho-5′- diphosphatase
: adenosine-5′-diphospho-5′- diphosphatase|adenosine-5′-diphospho-5′- diphosphatase
: DNA-3′-diphospho-5′-guanosine diphosphatase
: inosine/xanthosine triphosphatase
: mRNA 5′-phosphatase

3.6.2: In sulfonyl-containing anhydrides

3.6.3: Acting on acid anhydrides to catalyse transmembrane movement of substances

: phospholipid-translocating ATPase
EC 3.6.3.2: Now, P-type Mg²⁺ transporter
EC 3.6.3.3: Now, Cd²⁺-exporting ATPase
EC 3.6.3.4: Now, Cu²⁺-exporting ATPase
EC 3.6.3.5: Now, Zn²⁺-exporting ATPase
EC 3.6.3.6: Now, P-type H⁺-exporting transporter
EC 3.6.3.7: Now, P-type Na⁺ transporter
EC 3.6.3.8: Now, Ca²⁺-transporting ATPase
EC 3.6.3.9: Now, Na⁺/K⁺-exchanging ATPase
EC 3.6.3.10: Now, H⁺/K⁺-exchanging ATPase
EC 3.6.3.11: "Cl^–-transporting ATPase". The activity was only ever studied in crude extracts, and is an artifact
EC 3.6.3.12: Now, K⁺-transporting ATPase
EC 3.6.3.13:Identical to, phospholipid-translocating ATPase
EC 3.6.3.14: Now, H⁺-transporting two-sector ATPase
EC 3.6.3.15: Now, Na⁺-transporting two-sector ATPase
EC 3.6.3.16: Now, arsenite-transporting ATPase
EC 3.6.3.17: Now covered by various ABC-type monosaccharide transporters in sub-subclass EC 7.5.2
EC 3.6.3.18: Now, ABC-type oligosaccharide transporter
EC 3.6.3.19: Now, ABC-type maltose transporter
EC 3.6.3.20: Now, glycerol-3-phosphate-transporting ATPase
EC 3.6.3.21: Now, ABC-type polar-amino-acid transporter
EC 3.6.3.22: Now, ABC-type nonpolar-amino-acid transporter
EC 3.6.3.23: Now, oligopeptide-transporting ATPase
EC 3.6.3.24: Now, nickel-transporting ATPase
EC 3.6.3.25: Now, sulfate-transporting ATPase
EC 3.6.3.26: Now, nitrate-transporting ATPase
EC 3.6.3.27: Now, ABC-type phosphate transporter
EC 3.6.3.28: Now, ABC-type phosphonate transporter
EC 3.6.3.29: Now, molybdate-transporting ATPase
EC 3.6.3.30: Now, Fe³⁺-transporting ATPase
EC 3.6.3.31: Now, polyamine-transporting ATPase
EC 3.6.3.32: Now, quaternary-amine-transporting ATPase
EC 3.6.3.33: Now, vitamin B₁₂-transporting ATPase
EC 3.6.3.34: now recognized to be at least three separate enzymes, iron hydroxamate ABC transporter,, ferric enterobactin ABC transporter, and, ferric citrate ABC transporter
EC 3.6.3.35: Now, manganese-transporting ATPase
EC 3.6.3.36: Now, taurine-transporting ATPase
EC 3.6.3.37: Now, guanine-transporting ATPase
EC 3.6.3.38: Now, ABC-type capsular-polysaccharide transporter
EC 3.6.3.39: Now, lipopolysaccharide-transporting ATPase
EC 3.6.3.40: Now, teichoic-acid-transporting ATPase
EC 3.6.3.41: Now, heme-transporting ATPase
EC 3.6.3.42: Now, β-glucan-transporting ATPase
EC 3.6.3.43: Now, peptide-transporting ATPase
EC 3.6.3.44: Now, ABC-type xenobiotic transporter
EC 3.6.3.45: Now included with, xenobiotic-transporting ATPase
EC 3.6.3.46: Now, ABC-type Cd²⁺ transporter
EC 3.6.3.47: Now, fatty-acyl-CoA-transporting ATPase
EC 3.6.3.48: Now as α-factor-pheromone transporting ATPase
EC 3.6.3.49: Now, channel-conductance-controlling ATPase
EC 3.6.3.50: Now, protein-secreting ATPase
EC 3.6.3.51: Now, mitochondrial protein-transporting ATPase
EC 3.6.3.52: Now, chloroplast protein-transporting ATPase
EC 3.6.3.53: Now, Ag⁺-exporting ATPase
EC 3.6.3.54: Now, Cu⁺-exporting ATPase
EC 3.6.3.55: Now, tungstate-importing ATPase

3.6.4: Acting on acid anhydrides to facilitate cellular and subcellular movement

EC 3.6.4.1: Now, myosin ATPase
EC 3.6.4.2: Now, dynein ATPase
EC 3.6.4.3: Now, microtubule-severing ATPase
EC 3.6.4.4: Now, plus-end-directed kinesin ATPase
EC 3.6.4.5: Now, minus-end-directed kinesin ATPase
: vesicle-fusing ATPase
: peroxisome-assembly ATPase
EC 3.6.4.8: Now, proteasome ATPase
EC 3.6.4.9: Now, chaperonin ATPase
: non-chaperonin molecular chaperone ATPase
EC 3.6.4.11: Deleted, the activity has been shown not to take place
: DNA helicase
: RNA helicase

3.6.5: Acting on GTP to facilitate cellular and subcellular movement

EC 3.7: Acting on carbon-carbon bonds

EC 3.7.1: In ketonic substances

: oxaloacetase
: fumarylacetoacetase
: kynureninase
: phloretin hydrolase
: acylpyruvate hydrolase
: acetylpyruvate hydrolase
: β-diketone hydrolase
: 2,6-dioxo-6-phenylhexa-3-enoate hydrolase
: 2-hydroxymuconate-semialdehyde hydrolase
: cyclohexane-1,3-dione hydrolase
: cyclohexane-1,2-dione hydrolase
: cobalt-precorrin 5A hydrolase
: 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase
: 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase
EC 3.7.1.15: Now, -caryolan-1-ol synthase
EC 3.7.1.16: Now, oxepin-CoA hydrolase
: 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase
: 6-oxocamphor hydrolase
: 2,6-dihydroxypseudooxynicotine hydrolase
: 3-fumarylpyruvate hydrolase
: 6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase
: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (ring-opening)
: maleylpyruvate hydrolase
: 2,4-diacetylphloroglucinol hydrolase
: 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase
: 2,4-didehydro-3-deoxy-L-rhamnonate hydrolase
: neryl diphosphate diphosphatase
: 3-oxoisoapionate-4-phosphate transcarboxylase/hydrolase

EC 3.8: Acting on halide bonds

[EC 3.8.1]: Acting on halide bonds

EC 3.8.1.1: Covered by, haloalkane dehalogenase.
: (S)-2-haloacid dehalogenase
: haloacetate dehalogenase
EC 3.8.1.4: Now, thyroxine 5′-deiodinase
: haloalkane dehalogenase
: 4-chlorobenzoate dehalogenase
: 4-chlorobenzoyl-CoA dehalogenase
: atrazine chlorohydrolase
: (R)-2-haloacid dehalogenase
: 2-haloacid dehalogenase (configuration-inverting)
: 2-haloacid dehalogenase (configuration-retaining)

3.8.2: In phosphorus-halide compounds (deleted sub-subclass)

EC 3.8.2.1: Now, diisopropyl-fluorophosphatase

EC 3.9: act on phosphorus-nitrogen bonds

EC 3.9.1: Acting on phosphorus-nitrogen bonds (only sub-subclass identified to date)

: phosphoamidase
: protein arginine phosphatase
: phosphohistidine phosphatase

EC 3.10: Acting on sulfur-nitrogen bonds

EC 3.10.1: Acting on sulfur-nitrogen bonds (only sub-subclass identified to date)

EC 3.11: Acting on carbon-phosphorus bonds

EC 3.11.1: Acting on carbon-phosphorus bonds (only sub-subclass identified to date)

EC 3.12: Acting on sulfur-sulfur bonds

EC 3.12.1: Acting on sulfur-sulfur bonds (only sub-subclass identified to date)

: trithionate hydrolase

EC 3.13: Acting on carbon-sulfur bonds

EC 3.13.1: Acting on carbon-sulfur bonds (only sub-subclass identified to date)

: UDP-sulfoquinovose synthase
EC 3.13.1.2: Deleted, the activity is most probably attributable to, S-ribosylhomocysteine lyase
: 2′-hydroxybiphenyl-2-sulfinate desulfinase
: 3-sulfinopropanoyl-CoA desulfinase
: carbon disulfide hydrolase
: -S-L-cysteine hydrolase|-S-L-cysteine hydrolase
: Carbonyl sulfide hydrolase
: S-adenosyl-L-methionine hydrolase (adenosine-forming)
: S-inosyl-L-homocysteine hydrolase