Phosphoethanolamine/phosphocholine phosphatase
Phosphoethanolamine/phosphocholine phosphatase is an enzyme highly expressed in mineralizing cells. This enzyme is implicated in bone and cartilage formation and catalyses the following chemical reactions:
The enzyme is a member of the haloacid dehalogenase superfamily. Like other members of this superfamily it requires a metal ion for catalysis, which is usually Mg2+, it is also active in the presence of Co2+ or Mn2+ but exhibits a lower specific activity with these metal ions.