Assessing the impact of human genome annotation choice on RNA-seq expression estimates
Assessing the impact of human genome annotation choice on RNA-seq expression estimates is a scholarly work by May Wang, published in 2013 in ''BMC Bioinformatics''. The main subjects of the publication include Ensembl genome database project, genome annotation, RNA-Seq, annotation, genomics, genome browser, reference genome, biology, Cancer genome sequencing, gene, genome, long non-coding RNA, genetics, genome project, human genome, RNA sequencing, DNA annotation, methylation, RefSeq, and computational biology. The study (1) investigates the effect of different genome annotations on RNA-seq quantification and (2) provides guidelines for choosing a genome annotation based on research focus.