| School | Nickname | Location | Conference | Tournament appearance | Last appearance | Consecutive tournament appearances | Previous best performance |
| Albion College | Britons | Albion, MI | Michigan Intercollegiate Athletic Association | 1st | Debut | 1 | Debut |
| Ashland College | Eagles | Ashland, OH | Independent/Great Lakes Valley Conference | 2nd | 1976 | 1 | Regional third place |
| Brandeis University | Judges | Waltham, MA | Independent | 4th | 1978 | 4 | World Series Runner-Up |
| Stanislaus State College | Warriors | Turlock, CA | Independent | 4th | 1978 | 4 | National Champion |
| Claremont-Mudd-Scripps Colleges | Stags | Claremont, CA | Southern California Intercollegiate Athletic Conference | 2nd | 1978 | 2 | Regional third place |
| DePauw University | Tigers | Greencastle, IN | Independent | 3rd | 1978 | 3 | Regional third place |
| Eastern Connecticut State College | Warriors | Willimantic, CT | Independent | 4th | 1978 | 4 | Regional third place |
| Illinois Institute of Technology | Scarlet Hawks | Chicago, IL | Independent/Chicagoland Collegiate Athletic Conference | 1st | Debut | 1 | Debut |
| Ithaca College | Bombers | Ithaca, NY | Inedependent College Athletic Conference | 4th | 1978 | 4 | World Series Runner-Up |
| Lawrence University | Vikings | Appleton, WI | Midwest Collegiate Athletic Conference | 2nd | 1977 | 1 | Regional Fourth place |
| Mansfield State College | Mountaineers | Mansfield, PA | Independent/Pennsylvania State Athletic Conference | 2nd | 1976 | 1 | Regional Runner-Up |
| Marietta College | Pioneers | Marietta, OH | Ohio Athletic Conference | 4th | 1978 | 4 | World Series Runner-Up |
| Pace University | Setters | New York City, NY | Independent | 3rd | 1978 | 3 | Regional Fifth place |
| Rhode Island College | Anchormen | Providence, RI | New England State College Conference | 2nd | 1978 | 2 | Regional Fourth place |
| Glassboro State College | Profs | Glassboro, NJ | New Jersey State Athletic Conference | 4th | 1978 | 4 | National Champion |
| St. Olaf College | Oles | Northfield, MN | Minnesota Intercollegiate Athletic Conference | 3rd | 1978 | 3 | Regional third place |
| Stillman College | Tigers | Tuscaloosa, AL | Independent | 2nd | 1978 | 2 | Regional Fifth place |
| The College of Wooster | Fighting Scots | Wooster, OH | Ohio Athletic Conference | 3rd | 1978 | 3 | Regional Runner-Up |
| Trenton State College | Lions | Ewing, NJ | New Jersey State Athletic Conference | 1st | Debut | 1 | Debut |
| Lynchburg College | Hornets | Lynchburg, VA | Old Dominion Athletic Conference | 4th | 1978 | 4 | Regional Runner-Up |
| Upsala College | Vikings | East Orange, NJ | Middle Atlantic States Collegiate Athletic Conference | 3rd | 1978 | 2 | Regional third place |
| Virginia Wesleyan College | Marlins | Virginia Beach, VA | Dixie Intercollegiate Athletic Conference | 1st | Debut | 1 | Debut |
| Westfield State College | Owls | Westfield, MA | Massachusetts State Collegiate Athletic Conference | 4th | 1978 | 4 | Regional Runner-Up |
| University of Wisconsin-Oshkosh | Titans | Oshkosh, WI | Wisconsin State University Conference | 1st | Debut | 1 | Debut |