1480

Events

January 3 - King Louis XI buys the succession rights to the Duchy of Brittany from the Countess Nicole de Châtillon for 50,000 livres
February 4 - Pedro de Vera is appointed as the colonial Governor of Gran Canaria by the Spanish monarchs Ferdinand and Isabella, and directed to carry out the conquest of the Canary Islands and to end the fighting between the conquistadors who had taken the island in 1478.
March 3 - The Treaty of Lucerne is signed between the Duchy of Milan and the Old Swiss Confederation, 15 months after the Battle of Giornico. Milan cedes the Leventina District to the Canton of Uri.
March 6 - The Treaty of Toledo is signed as Ferdinand and Isabella of Spain recognize the African conquests of Afonso V of Portugal, and he cedes the Canary Islands to Spain.
March 17 - Lorenzo the Magnificent, List of [heads of state of Florence|Lord] of the Republic of Florence, and King Ferrante of Naples agree to an alliance between the two Italian nations, and to end the ongoing war that had started in 1479. Lorenzo had traveled to Naples in December to reach a treaty to end the war.

April 6 - King Afonso V of Portugal orders his navy to "capture anyone trading illegally in Africa, and to throw the goods and ship's crew into the sea.
May 3 - Pedro del Algaba, the Spanish colonial Governor of the Canary Islands, is arrested by Juan Rejón, and is executed on Rejón's orders on May 20.
May 23 - The Siege of Rhodes begins as the Ottoman Turk invading force begins its invasion, introducing the psychological warfare of coming ashore with "loud martial music" and the shrieking cries of dervishes.
June 20 - The Senate of the Republic of Venice votes to approve the transfer of ownership of the island of Santorini to Domenico Pisani. The island was the dowry given to Pisani for the marriage of Fiorenza Crispo, by Firenzo's father, Giacomo III Crispo, Duke of the Archipelago, a set of 18 of the 20 inhabited Cyclades islands in the Aegean Sea.

July 28
* Mehmed II fails in his attempt to capture Rhodes from the Knights of Rhodes.
* An Ottoman army lands near Otranto in southern Italy. Pope Sixtus IV calls for a crusade to drive the Ottomans away. Otranto falls on August 12 after a 15-day siege.
August 14 - Two days after Ottoman troops had broken a siege and taken control of the village of Otranto in southern Italy, led by Gedik Ahmed Pasha, carry out the massacre of 813 inhabitants who had refused to convert from Christianity to Islam.
September 27 - The co-rulers of most of Spain, Ferdinand II of Aragon and Isabella I of Castile initiate the Spanish Inquisition to look for heretics and unconverted Jews, appointing the Dominican Order clerics Miguel de Morillo and Juan de San Martín to serve as the first two inquisitors.

October 8 - The Great Stand on the Ugra River begins as troops of the Grand Duchy of Moscow, led by the Grand Duke Ivan III and General Ivan Molodoy battle against the invading Mongol armies of the Golden Horde, led by their ruling monarch, Akhmat Khan. The invasion began after Ivan III stopped paying tribute to the Horde. The Theotokos of Vladimir icon is credited with saving Moscow. The standoff between the troops lasts five weeks before Akhmat and the Mongol troops retreat.
November 3 - Ludovico Sforza succeeds his sister-in-law, Bona of Savoy, as regent of Milan for his 12-year-old nephew Gian Galeazzo Sforza, Bona's son and the Duke of Milan.
November 8 - After reinforcements from Lithuania fail to arrive for more than four weeks, Akhmat Khan orders the Mongols to end their attempt to conquer the Grand Duchy of Moscow.
December 7 - During the [Đại Việt–Lan Xang War (1479–1484)|war between Dai Viet and Lan Xang], Emperor Xianxong of Ming dyansty China is informed by his envoys that Dai Viet had subdued Lan Xang and was preparing to invade Lan Na (now part of northern Thailand. China responds by sending intelligence agents to spy on Dai Viet.