Tryptophan–tRNA ligase
In enzymology, a tryptophan–tRNA ligase is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are ATP, -tryptophan, and tRNA, whereas its 3 products are AMP, diphosphate, and -tryptophyl-tRNA.
This enzyme belongs to the family of ligases, to be specific those forming carbon–oxygen bonds in aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is -tryptophan:tRNA ligase . Other names in common use include tryptophanyl-tRNA synthetase, -tryptophan-tRNA ligase , tryptophanyl-transfer ribonucleate synthetase, tryptophanyl-transfer ribonucleic acid synthetase, tryptophanyl-transfer RNA synthetase, tryptophanyl ribonucleic synthetase, tryptophanyl-transfer ribonucleic synthetase, tryptophanyl-tRNA synthase, tryptophan translase, and TrpRS. This enzyme participates in tryptophan metabolism and aminoacyl-tRNA biosynthesis.