Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA
Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA is a scholarly work by Aviv Regev, Eric Lander, Rahul Satija, Schraga Schwartz, Maxwell R Mumbach, Mitchell Guttman, and Jesse Engreitz, published in 2014 in ''Cell''. The main subjects of the publication include biology, Pseudouridine synthase CBF5 YLR175W, RNA splicing, Dyskerin pseudouridine synthase 1, Pseudouridine synthase PUS7 YOR243C, Pseudouridine synthase PUS4 YNL292W, transfer RNA, non-coding RNA, ribonucleic acid, transcriptome, small nucleolar RNA, Pseudouridine synthase PUS5 YLR165C, Pseudouridine synthase PUS9 YDL036C, gene, methylation, pseudouridine, pseudouridine synthase activity, genetics, computational biology, ribosome, and Pseudouridine synthase PUS1 YPL212C. The authors validate Ψ-seq with spike-ins and de novo identification of previously reported positions and discover hundreds of unique sites in human and yeast mRNAs and snoRNAs.