Family Guy season 21
The twenty-first season of the American animated television series Family Guy aired on Fox from September 25, 2022, to May 7, 2023. This season also featured the series' 400th episode.
The series follows the dysfunctional Griffin family, consisting of father Peter, mother Lois, daughter Meg, son Chris, baby Stewie, and the family dog Brian, who reside in their hometown of Quahog, Rhode Island.
Season twenty-one premiered the run of the twentieth production season, which is executive produced by Seth MacFarlane, Alec Sulkin, Richard Appel, Steve Callaghan, Danny Smith, Kara Vallow, Mark Hentemann, Tom Devanney, and Patrick Meighan. Sulkin and Appel returned as the series' showrunners.
The season premiered on ITV2 on August 7, 2023.
The milestone 400th episode was actually pitched by Seth MacFarlane himself.
Voice cast and characters
- Seth MacFarlane as Peter Griffin, Brian Griffin, Stewie Griffin, Glenn Quagmire, Tom Tucker, Carter Pewterschmidt, Dr. Hartman, Seamus
- Alex Borstein as Lois Griffin, Barbara "Babs" Pewterschmidt, Elle Hitler
- Seth Green as Chris Griffin
- Mila Kunis as Meg Griffin
- Mike Henry as John Herbert
- Patrick Warburton as Joe Swanson
- Arif Zahir as Cleveland Brown
Supporting characters
- Johnny Brennan as Mort Goldman
- Gary Cole as Principal Shepherd
- Sam Elliott as Mayor Wild West
- Sanaa Lathan as Donna Tubbs-Brown
- Rachael MacFarlane as Miss Tammy
- Peter Macon as Preston Lloyd
- Marlee Matlin as Stella
- Chris Parnell as Doug
- Kevin Michael Richardson as Jerome
- Jennifer Tilly as Bonnie Swanson