RH-34


RH-34 is a compound which acts as a potent and selective partial agonist for the 5-HT2A serotonin receptor subtype. It was derived by structural modification of the selective 5-HT2A antagonist ketanserin, with the 4-piperidine moiety replaced by the N- pharmacophore found in such potent 5-HT2A agonists as NBOMe-2C-B and NBOMe-2C-I. This alteration was found to retain 5-HT2A affinity and selectivity, but reversed activity from an antagonist to a moderate efficacy partial agonist.

Interactions

Society and culture

Legal status

RH-34 is a controlled substance in Hungary and Brazil. It is not a controlled substance in Canada as of 2025. It is also not an explicitly controlled substance in the United States.