Pseudouridylate synthase
In enzymology, a pseudouridylate synthase is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are uracil and D-ribose 5-phosphate, whereas its two products are pseudouridine 5'-phosphate and H2O.
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is uracil hydro-lyase . Other names in common use include pseudouridylic acid synthetase, pseudouridine monophosphate synthetase, 5-ribosyluracil 5-phosphate synthetase, pseudouridylate synthetase, upsilonUMP synthetase, and uracil hydro-lyase . This enzyme participates in pyrimidine metabolism.As of late 2007, 22 structures have been solved for this class of enzymes, with PDB accession codes,,,,,,,,,,,,,,,,,,,,, and.
