Oxalate oxidase


In enzymology, oxalate oxidase is an oxalate degrading enzyme that catalyzes the chemical reaction:
The two substrates of this enzyme are oxalic acid and oxygen. Its products are carbon dioxide and hydrogen peroxide.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with oxygen as acceptor. The systematic name of this enzyme class is oxalate:oxygen oxidoreductase. Other names in common use include aero-oxalo dehydrogenase, and oxalic acid oxidase. This enzyme participates in glyoxylate and dicarboxylate metabolism. It uses Manganese as a cofactor.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes,,, and.