Actor Award for Outstanding Performance by a Female Actor in a Leading Role
The Actor Award for Outstanding Performance by a Female Actor in a Leading Role in a Motion Picture is an award presented annually by the Screen Actors Guild. It has been presented since the 1st Screen Actors Guild Awards in 1995 to a female actor who has delivered an outstanding performance in a leading role in a film released that year.
The award has been presented 30 times, and 27 actresses have won the award. Jodie Foster was the award's first winner for Nell. The most recent winner is Demi Moore who won for her performance in The Substance. Frances McDormand, Renée Zellweger, and Viola Davis have all won the award twice. Meryl Streep has the most nominations with ten.
Multiple winners
;2 wins- Viola Davis, Ma Rainey's Black Bottom )
- Frances McDormand, Three Billboards Outside Ebbing, Missouri )
- Renée Zellweger, Judy )
Multiple nominees
Note: Winners are indicated in bold type.;Two nominations
- Amy Adams, Hillbilly Elegy )
- Joan Allen, The Contender )
- Emily Blunt, Mary Poppins Returns )
- Sandra Bullock, Gravity )
- Jessica Chastain, The Eyes of Tammy Faye )
- Glenn Close, The Wife )
- Olivia Colman, The Lost Daughter )
- Marion Cotillard, Rust and Bone )
- Cynthia Erivo, Wicked )
- Lady Gaga, House of Gucci )
- Angelina Jolie, Changeling )
- Diane Keaton, Something's Gotta Give )
- Jennifer Lawrence, Silver Linings Playbook )
- Natalie Portman, Jackie )
- Margot Robbie, Barbie )
- Saoirse Ronan, Lady Bird )
- Susan Sarandon, Dead Man Walking )
- Emma Thompson, Saving Mr. Banks )
- Naomi Watts, The Impossible )
- Reese Witherspoon, Wild )
- Viola Davis, Ma Rainey's Black Bottom, The Woman King )
- Nicole Kidman, Rabbit Hole, Being the Ricardos )
- Frances McDormand, Three Billboards Outside Ebbing, Missouri, Nomadland )
- Julianne Moore, Far from Heaven, Still Alice )
- Carey Mulligan, Promising Young Woman, Maestro )
- Emma Stone, Poor Things, Bugonia )
- Hilary Swank, Million Dollar Baby, Conviction )
- Charlize Theron, North Country, Bombshell )
- Renée Zellweger, Chicago, Judy )
- Annette Bening, Being Julia, The Kids Are All Right, Nyad )
- Helen Mirren, The Last Station, Hitchcock, Woman in Gold )
- Kate Winslet, Eternal Sunshine of the Spotless Mind, Little Children, Revolutionary Road )
- Cate Blanchett, Elizabeth: The Golden Age, Blue Jasmine, Carol, Tár )
- Judi Dench, Iris, Mrs Henderson Presents, Notes on a Scandal, Philomena, Victoria & Abdul )
- Meryl Streep, The Bridges of Madison County, One True Thing, Music of the Heart, The Devil Wears Prada, Doubt, Julie & Julia, The Iron Lady, August: Osage County, Florence Foster Jenkins )