Primetime Emmy Award for Outstanding Lead Actress in a Comedy Series
This is a list of winners and nominees of the Primetime Emmy Award for Outstanding Lead Actress in a Comedy Series. Beginning with 1966, leading actresses in comedy have competed alone. However, these comedic performances included actresses from miniseries, telefilms, and guest performers competing against main cast competitors. Such instances are marked below:# – Indicates a performance in a Miniseries or Television film, prior to the category's creation§ – Indicates a performance as a guest performer, prior to the category's creation
The 71st Primetime Emmy Awards were the first and, so far, only Emmys where there is no representation from any of the big four broadcast networks.
Programs with multiple wins
;6 winsVeep;5 winsMurphy Brown
;4 winsHacksMad About You
;3 winsAll in the FamilyFather Knows BestThe Golden GirlsThe Mary Tyler Moore Show
;2 winsCheersThe Dick Van Dyke ShowEverybody Loves RaymondThe Ghost & Mrs. MuirHazelKate & AllieThe Lucy Show
- ''Taxi''
Performers with multiple wins
;7 wins;5 wins
;4 wins
;3 wins
;2 wins
Programs with multiple nominations
;15 nominationsThe Golden Girls;9 nominationsCheers
;8 nominationsAll in the Family
;7 nominations30 RockEverybody Loves RaymondThe JeffersonsMad About YouMalcolm in the MiddleThe Mary Tyler Moore ShowMurphy BrownSoapVeep
;6 nominationsBewitchedNurse JackieParks and RecreationSex and the City
;5 nominationsBlack-ishThe Days and Nights of Molly DoddGrace and FrankieKate & AllieThe Marvelous Mrs. MaiselMaudeThe New Adventures of Old ChristineWill & Grace
;4 nominationsAbbott ElementaryDead to MeDesperate HousewivesThe Donna Reed ShowEllenThe George Burns and Gracie Allen ShowHacksHome ImprovementI Love LucyThe Loretta Young ShowThe Lucy ShowRhodaRoseanneThat Girl
;3 nominationsAlly McBealCybillDharma & GregThe Dick Van Dyke ShowFather Knows BestFriendsGirlsHazelInsecureMike & MollyMomOur Miss BrooksPrivate SecretaryTaxiWeeds
;2 nominationsThe BearBetter ThingsThe Beverly HillbilliesThe Bob Newhart ShowBrooklyn BridgeThe ComebackThe Cosby ShowDecember BrideDesigning WomenThe Flight AttendantGet SmartThe Ghost & Mrs. MuirGimme a Break!Inside Amy SchumerLove, SidneyMr. Adams and EveThe NannySamantha Who?Schitt's CreekUgly BettyUnbreakable Kimmy Schmidt
Performers with multiple nominations
;12 nominations;10 nominations
;9 nominations
;8 nominations
;7 nominations
;6 nominations
;5 nominations
- Christina Applegate
- Rachel Brosnahan
- Blair Brown
- Debra Messing
- Elizabeth Montgomery
- Tracee Ellis Ross
- Gracie Allen
- Eve Arden
- Roseanne Barr
- Quinta Brunson
- Ellen DeGeneres
- Valerie Harper
- Katherine Helmond
- Shelley Long
- Rue McClanahan
- Donna Reed
- Patricia Richardson
- Jean Smart
- Ann Sothern
- Marlo Thomas
- Lily Tomlin
- Loretta Young
- Jennifer Aniston
- Shirley Booth
- Jane Curtin
- Cathryn Damon
- Lena Dunham
- Jenna Elfman
- Calista Flockhart
- Allison Janney
- Melissa McCarthy
- Mary-Louise Parker
- Issa Rae
- Cybill Shepherd
- Jane Wyatt
- Pamela Adlon
- Delta Burke
- Spring Byington
- Nell Carter
- Toni Collette
- Kaley Cuoco
- Fran Drescher
- Ayo Edebiri
- Barbara Feldon
- America Ferrera
- Felicity Huffman
- Ellie Kemper
- Lisa Kudrow
- Swoosie Kurtz
- Hope Lange
- Ida Lupino
- Natasha Lyonne
- Catherine O'Hara
- Suzanne Pleshette
- Phylicia Rashad
- Marion Ross
- Irene Ryan
- Susan Saint James
- Amy Schumer