Ornithine cyclodeaminase


The enzyme ornithine cyclodeaminase catalyzes the chemical reaction
L-ornithine L-proline + NH4+

This enzyme belongs to the family of lyases, specifically ammonia lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is Lornithine ammonia-lyase . Other names in common use include ornithine cyclase, ornithine cyclase , and L-ornithine ammonia-lyase . This enzyme participates in arginine and proline biosynthesis. It employs one cofactor, NAD+.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and.