One reference genome is not enough
One reference genome is not enough is a scholarly work by Xiaofei Yang, published in 2019 in ''Genome Biology''. The main subjects of the publication include personal genomics, evolutionary biology, Cancer genome sequencing, genome, ENCODE, genomic structural variation, reference genome, ribosome, biology, genomics, human genome, human genetics, Genome Biology, genetics, computational biology, and RNA sequencing. A recent study on human structural variation indicates insufficiencies and errors in the human reference genome, GRCh38, and argues for the construction of a human pan-genome.