Mapping and sequencing of structural variation from eight human genomes
Mapping and sequencing of structural variation from eight human genomes is a scholarly work by Tina Graves, Evan E. Eichler, Francesca Antonacci, Jeffrey M. Kidd, Eric Haugen, Kevin McKernan, Can Alkan, David Altshuler, John Stamatoyannopoulos, James C Mullikin, Deborah A Nickerson, Richard K. Wilson, E. Gustafson, Steven A McCarroll, Troy Zerr, Maika Malig, Nick Sampas, Laurakay Bruhn, and Gregory M. Cooper, published in 2008 in ''Nature''. The main subjects of the publication include RNA sequencing, copy-number variation, human genome, genetic variation, biology, 1000 Genomes Project, reference genome, evolutionary biology, genome, DNA sequencing, computational biology, genomic structural variation, Variation (astronomy), genotyping, genetics, and human genetic variation. The authors discover 525 new insertion sequences that are not present in the human reference genome and show that many of these are variable in copy number between individuals.