Long-Range Signaling Activation and Local Inhibition Separate the Mesoderm and Endoderm Lineages
Long-Range Signaling Activation and Local Inhibition Separate the Mesoderm and Endoderm Lineages is a scholarly work by Caroline S. Hill, published in 2017 in ''Developmental Cell''. The main subjects of the publication include genetics, epigenetics, mesoderm, germ layer, signal transduction, neoplastic stem cells, cell biology, endoderm, FGF and mesoderm formation, and biology. The authors show that Nodal induces long-range Fgf signaling while simultaneously inducing the cell-autonomous Fgf signaling inhibitor Dusp4 within the first two cell tiers from the margin.