List of University of Pittsburgh alumni
This list of University of Pittsburgh alumni includes notable graduates, non-graduate former students, and current students of the University of Pittsburgh, a state-related research university in Pittsburgh, Pennsylvania.
Arts and entertainment
- Dilruba Ahmed - Bangladeshi poet and author
- Geri Allen – jazz composer, educator, and pianist
- Hervey Allen – author, best known for Anthony Adverse
- Olivia Anakwe – fashion model
- Joseph Bathanti – poet, writer, professor; NC Poet Laureate, 2012–2014
- Peter Beagle – Hugo Award-winning fantasist and author of novels, nonfiction, and screenplays
- Jeff Bergman – voice actor who provides modern-day voices of classic cartoon characters including Bugs Bunny and Daffy Duck
- Frank E. Bolden - journalist known for his work as a World War II correspondent for the Pittsburgh Courier
- DJ Bonics – a hip hop DJ for Wiz Khalifa and radio DJ.
- Mark Bulwinkle – graphic artist and sculptor
- Michael Chabon – Pulitzer Prize-winning author of The Amazing Adventures of Kavalier & Clay, The Yiddish Policemen's Union, and The Mysteries of Pittsburgh
- Murray Chass – award-winning baseball journalist for The New York Times
- Michael Clinton - writer and photographer
- Bill Cullen – host of many television game shows
- Virginia Cuthbert – artist
- Stephen Dau – writer
- Jim Donovan – professional drummer and percussionist, best known as the former drummer and one of the founding members of the band Rusted Root
- Morton Fine - screenwriter/producer, winner of the Writers Guild of America Award for The Pawnbroker
- Sharon G. Flake – award-winning author of young adult literature
- Jack Gilbert – award-winning poet
- Lester Goran – author
- Gabbie Hanna – YouTuber, singer-songwriter, author, & internet personality
- Ernie Hawkins – blues guitarist and singer
- Terrance Hayes – poet whose books have won National Book Award for Poetry and National Poetry Series
- Samuel John Hazo – novelist, playwright, first poet laureate of Commonwealth of Pennsylvania
- Paul Hertneky – writer
- Frederick A. Hetzel – University Press publisher
- Eddie Ifft – stand-up comedian, athlete
- John Irving – author of The Cider House Rules and The World According to Garp; recipient of an Academy Award for Best Adapted Screenplay and a National Book Award for Fiction
- Nicole Johnson – Miss America 1999 and diabetes advocate
- Gene Kelly – Academy Award-winning dancer, actor, singer, film director, producer and choreographer, perhaps best known for performance in Singin' in the Rain
- Chris Kuzneski – New York Times best-selling author
- Jeanne Marie Laskas – award-winning columnist, journalist, and author
- Lorin Maazel – conductor, violinist, and composer, New York Philharmonic
- Herb Magidson – lyricist, won first Academy Award for Best Original Song, in 1934
- Kellee Maize – musician, rapper and hip-hop artist
- Allison McAtee – actress, model, CSI: Miami, Life, Hell Ride, Bloomington
- Bebe Moore Campbell – author and journalist
- Jenna Morasca – actress, model and winner of Survivor: The Amazon
- Laci Mosley – actress, comedian and podcaster
- Thaddeus Mosley – sculptor who works mostly in wood
- Brett Murphy - Member of Pulitzer Prize winning team and individual finalist for the Pulitizer for journalism.
- Ethelbert Nevin – pianist and composer, left school after one year
- David Newell – actor, Mr. McFeely on Mister Rogers' Neighborhood
- Beth Ostrosky – model, actress, and wife of Howard Stern
- Barbara Paul – writer
- Susan Ressler - photographer
- Ed Roberson – award-winning poet
- Leo Robin – composer and songwriter
- Fred Rogers – host of Mister Rogers' Neighborhood
- Zelda Rubinstein – actress best known for Poltergeist, earned bachelor's degree in bacteriology
- Neal Russo – sportswriter for St. Louis Post-Dispatch, Sporting News and Sports Illustrated
- Justin Sane – singer, guitarist of punk band Anti-Flag
- Julie Sokolow – documentary filmmaker, musician, and writer
- Brandon Som – Pulitzer Prize winning poet.
- Jack Stauber – YouTuber, singer-songwriter, and animator most well known for his song "Buttercup" and Adult Swim collaborations
- Robert Sterling – actor best known for Topper
- Gerald Stern – National Book Award-winning poet
- Bill Strickland – founder of Manchester Craftsmen's Guild, an agency that inspires teenagers through the arts; board member of National Endowment for the Arts; awarded MacArthur prize
- Benjamin Tatar – actor
- Alaska Thunderfuck – drag performer, musician, winner of RuPaul's Drag Race: All Stars
- Regis Toomey – motion picture and television actor who appeared in over 180 films
- Jerome "Jero" White – Japanese pop artist known for fusion of hip-hop and enka
- Wang Xiaobo – writer
Athletics
- Steven Adams – NBA starting center for Memphis Grizzlies
- Britt Baker – professional wrestler currently signed with All Elite Wrestling
- Adam Bisnowaty – NFL football player for Carolina Panthers
- DeJuan Blair – power forward for Dallas Mavericks; consensus first-team basketball All-American in 2008–09
- Matthew Bloom – professional wrestler and San Diego Chargers football player
- Antonio Bryant – wide receiver for Tampa Bay Buccaneers and Fred Biletnikoff Award winner
- Clifford Carlson – Pitt basketball head coach, two national championships and one Final Four team
- Marcus Carr – basketball player in the Israeli Basketball Premier League
- James Conner – Running back for the Arizona Cardinals
- Jason Conti – Major League Baseball player
- Beano Cook – ABC Sports and ESPN sports commentator
- Myron Cope – Hall of Fame Pittsburgh Steelers broadcaster
- Hailey Davidson - Defender for the Dallas Trinity FC
- Mike Ditka – football player for Pitt and Chicago Bears, NFL coach, broadcaster, member of Pro Football Hall of Fame
- Aaron Donald – All-pro defensive end for the Los Angeles Rams
- Tony Dorsett – member of Pro Football Hall of Fame; Heisman Trophy, Maxwell Award, and Walter Camp Award winner
- Herb Douglas – bronze medalist in long jump at 1948 Summer Olympics
- Larry Fitzgerald – wide receiver for the Arizona Cardinals, Walter Camp Award and Fred Biletnikoff Award winner
- Bill Fralic – Atlanta Falcons offensive lineman, member of College Football Hall of Fame
- Marshall Goldberg – two-time national champion and All-American, four-time All-Pro Chicago Cardinals running back and defensive back, member of 1947 NFL championship team, member of College Football Hall of Fame
- Aaron Gray – former center for the NBA's Detroit Pistons
- Hugh Green – pro football player; Lombardi Award, Maxwell Award, and Walter Camp Award winner
- Bobby Grier – Pitt football player, first African-American to play in Sugar Bowl
- Art Griggs – Major League Baseball player
- Russ Grimm – four-time Super Bowl-winning offensive lineman with Washington Redskins, assistant coach of Arizona Cardinals
- Mouhamadou Gueye - forward for the Toronto Raptors
- Damar Hamlin – safety for the Buffalo Bills
- Don Hennon – two-time All-American basketball guard and Helms Foundation Basketball Hall of Fame inductee
- Craig Heyward - NFL running back
- Dick Hoblitzel – Major League Baseball player for Cincinnati Reds and Boston Red Sox, MVP for the Reds
- Chuck Hyatt – three-time basketball All-American under Coach Doc Carlson, member of Basketball Hall of Fame
- Russ Kemmerer – Major League Baseball player
- Roger Kingdom – sprinter and hurdler, two-time Olympic gold medalist, former 110 m high hurdles world record holder
- Billy Knight – ABA and NBA basketball player, GM of Atlanta Hawks
- Andy Lee, football punter for the San Francisco 49ers of the National Football League
- Dion Lewis – running back for the Tennessee Titans
- Bill Maas – defensive tackle for Kansas City Chiefs and Green Bay Packers
- Ken Macha – former Major League Baseball player and manager
- Bob Malloy – Major League Baseball pitcher
- Dan Marino – quarterback for Pitt and Miami Dolphins, member of Pro Football Hall of Fame and television commentator
- Curtis Martin – pro football running back, fourth leading rusher of all time
- Mark May – ESPN sports commentator, football player, Outland Trophy winner
- LeSean McCoy – former running back for Buffalo Bills, Kansas City Chiefs, Philadelphia Eagles, and Tampa Bay Buccaneers
- George "Doc" Medich – Major League Baseball player
- Johnny Miljus – Major League Baseball player
- Sean Miller – basketball player at Pitt and head basketball coach at Arizona
- Bill Osborn – pro footballer, scout and color analyst
- Sam Parks Jr. – pro golfer, won U.S. Open in 1935 at Oakmont
- Johan Peñaranda - pro footballer, goalkeeper for FC Tulsa
- Kenny Pickett - Philadelphia Eagles quarterback
- Cumberland Posey – member of National Baseball Hall of Fame, player, manager, and team owner in Negro leagues, professional basketball player and team owner
- Darrelle Revis – defensive back for New York Jets
- Richard Rydze – Olympic silver medalist in diving at 1972 Summer Olympics, men's 10 meter platform
- Joe Schmidt – NFL player and head coach of Detroit Lions, 1967–1973
- Marty Schottenheimer – head coach of four NFL teams
- Jabaal Sheard – defensive end for the Indianapolis Colts
- Trecia-Kaye Smith – long jump and triple jump, seven-time NCAA national champion, 15-time All-American, 4 national indoor titles, 2004 Olympics fourth place, 2007 IAFF Champion, named to USTF Silver Anniversary Team in 2007
- Sal Sunseri – college and professional football coach
- Jock Sutherland – Hall of Fame football coach, All-American football player; Pitt Professor of Dentistry
- Steve Swetonic – Major League Baseball player
- Joe Walton – head coach of New York Jets, 1983–1989
- Dave Wannstedt – coach for several NFL and college teams, including University of Pittsburgh
- John Woodruff – gold medalist in 800 meters at 1936 Berlin Olympics
- Sam Young – small forward for Indiana Pacers; 2008 Big East Tournament MVP
Business
- Kevin G. McAllister – EVP The Boeing Company, President & CEO Boeing Commercial Airplanes
- Walter Arnheim – Mobil Oil executive, corporate and non-profit advisor
- Susan Arnold – Vice Chairman of P&G, ranked 10th among the 50 most powerful women in business by Fortune
- George Barco – cable television executive who played a key role in development of the industry
- Yolanda Barco – cable television executive
- Erik Buell – engineer, founder and chairman of Buell Motorcycle Company, a subsidiary of Harley-Davidson
- Marc Chandler – foreign exchange market analyst, writer, and speaker
- George Hubbard Clapp – aluminium industry pioneer
- Pat Croce – entrepreneur, author, TV personality, and former president of the Philadelphia 76ers
- Mark Cuban – businessman and investor, owner of Dallas Mavericks NBA franchise
- William S. Dietrich II – industrialist and philanthropist
- Ning Gaoning – Chairman of COFCO International Limited, 2009 CNBC Asia Pacific's Asia Business Leader of the Year
- Joseph A. Hardy III – Founder and CEO of 84 Lumber and Nemacolin Woodlands Resort.
- Frances Hesselbein – President and CEO of Leader to Leader Institute, former CEO for the Girl Scouts of the USA, and Presidential Medal of Freedom winner
- Dawne Hickton – vice chair, President, CEO of RTI International Metals
- Emmett Leahy, American archivist and entrepreneur, pioneer in the discipline of records management.
- Kevin March – CFO and Senior Vice-President of Texas Instruments
- Andrew W. Mellon – banker, philanthropist, U.S. Secretary of the Treasury, university trustee, donor, and founder of the Mellon Institute of Industrial Research
- Richard B. Mellon – banker, philanthropist, university trustee, founder of Mellon Institute of Industrial Research
- Thomas Mellon – founder of Mellon Financial, judge
- Larry Merlo – President and CEO of CVS Health
- Arturo C. Porzecanski – 2005 Legacy Laureate, pioneer in emerging markets research on Wall Street, former Chief Economist at ABN AMRO
- Al Primo – television news executive credited with creating "Eyewitness News" format
- Art Rooney II – president and co-owner of the NFL's Pittsburgh Steelers
- Brent Saunders – CEO of Bausch & Lomb; former President of Schering-Plough Healthcare Products
- Kevin W. Sharer – Chairman of Amgen
- Jagdish Sheth – internationally recognized business consultant, author and educator
- Sung Won Sohn – member of Council of Economic Advisers during Nixon administration
- John A. Swanson – founder and retired President of ANSYS, innovator of finite element simulation software and technologies designed to optimize product development processes; winner of John Fritz Medal in engineering
- Burton Tansky – President and Chief Executive Officer, The Neiman Marcus Group, Inc.
- David Tepper – speculator, hedge fund manager; gave naming donation to Tepper School of Business, owner of the NFL's Carolina Panthers and the MLS's Charlotte FC.
- Thomas Usher – Chairman of U.S. Steel and Marathon Oil; Director of Extra Mile Education Foundation and Boy Scouts of America
- David Wilstein – real estate developer
- Tung Chao Yung – Chinese shipping magnate, founder of the Orient Overseas Line, and owner of the largest ship ever built
Education
- Bowman Foster Ashe – first president of the University of Miami
- Stanley F. Battle – educator, author, activist, leader of North Carolina Agricultural and Technical State University, Coppin State University and Southern Connecticut State University
- Steven C. Beering – president emeritus, Purdue University and former dean of the Indiana University School of Medicine
- Todd H. Bullard – former president of Potomac State College and Bethany College
- Carol A. Cartwright – president of Kent State University, 1991–2006
- Paul Russell Cutright – historian and biologist
- Teresa Abi-Nader Dahlberg – 11th president of the University of Tampa
- Helen Faison, first African American, first woman to become superintendent of Pittsburgh district schools
- Claire Finkelstein, professor at the University of Pennsylvania Law School
- Christine Fulwylie-Bankston – educator, writer, civil rights activist
- Adam Herbert – president of Indiana University
- Young Woo Kang – special education expert; author; former policy advisor of National Council on Disability
- Ambrose King – former vice-chancellor of Chinese University of Hong Kong
- Jacqueline Liebergott – president of Emerson College
- Michael Lovell – former chancellor of University of Wisconsin–Milwaukee, president of Marquette University
- Barry McCarty – former president of Cincinnati Christian University and national radio host
- Jay F. W. Pearson – former president of University of Miami
- M. Richard Rose – former president of Alfred University and the Rochester Institute of Technology
- Brian Segal – publisher and former President of Ryerson Polytechnical Institute and the University of Guelph
- Michael Slinger – director of law library at Widener Law, former President of ALL-SIS and Ohio Regional Association of Law Libraries
- Peter J Woolley political scientist, founder of PublicMind
History
- Leonard Baker – Pulitzer Prize-winning biographer
- Paul Russell Cutright – historian and biologist
- Kenneth Sacks – Professor of History and Classics, Brown University
Military
- Gust Avrakotos – CIA agent responsible for arming Afghan mujaheddin in 1980s
- Samuel W. Black – colonel, hero of Mexican and [American American Civil War|Civil War|Civil] wars
- Patricia Horoho – Army's 43rd Surgeon General, commanding general of [United States United States Army|Army Medical Command|U.S. Army Medical Command]
- Nicholas P. Kafkalas – US Army major general
- Thomas J. Lynch – Army Air Forces lieutenant colonel and a flying ace of World War II; Distinguished Service Cross recipient
- Roscoe Robinson, Jr. – first African-American four-star general
- James Martinus Schoonmaker – Civil War Medal of Honor winner
- Joseph "Colonel Joe" H. Thompson – Medal of Honor recipient, College Football Hall of Fame inductee
- Boyd Wagner – first Army Air Forces fighter ace of World War II; Distinguished Service Cross recipient
Philosophy
- Nancy Cartwright – MacArthur Fellowship-winning philosopher noted for her work in philosophy of science, philosophy of economics, and philosophy of physics
- Patricia Churchland – 1991 MacArthur Prize-winning philosopher noted for her work in philosophy of mind and neurophilosophy; associated with a school of thought called eliminativism or eliminative materialism
- Stephen Hetherington, philosopher noted for his work in epistemology, emeritus professor in the school of humanities and languages at the University of New South Wales.
- Sandra Mitchell – professor and chair of the department of History and Philosophy of Science
- Holmes Rolston III – Templeton Prize-winning philosopher best known for his contributions to environmental ethics and the relationship between science and religion
- Ernest Sosa – international leader in virtue epistemology, inaugural winner of the Rescher Prize in Philosophy
Politics, law, and activism
- Ruggero J. Aldisert – judge on United States Court of Appeals for the Third Circuit; adjunct professor at School of Law
- Anne X. Alpern - Pennsylvania Attorney General and Pennsylvania Supreme Court justice; first woman to serve as a state attorney general
- Hanan Al-Ahmadi - Assistant Speaker of the Consultative Assembly of Saudi Arabia
- W. Thomas Andrews - Pennsylvania State Senator
- Eugene Atkinson – member of House of Representatives from Pennsylvania
- Gust Avrakotos – case officer CIA; known for massive arming of Afghan Mujahideen in 1980s in Soviet–Afghan War, chronicled in book Charlie Wilson's War: The Extraordinary Story of the Largest Covert Operation in History by George Crile
- Max Baer – Justice on Pennsylvania Supreme Court
- Derrick Bell – law professor, first tenured black professor at Harvard Law School, dean of Oregon Law School
- Michael Bilirakis – [United States Republican Party (United States)|Republican Party|Republican] member of United States House of Representatives
- Samuel W. Black – seventh Governor of Nebraska Territory
- Henry Marie Brackenridge – was an American writer, lawyer, judge, superintendent, and U.S. Congressman.
- Frank Buchanan – [United States United States Democratic Party|Democratic Party|Democratic] member of U.S. House of Representatives and Mayor of McKeesport, Pennsylvania
- Joseph Buffington – two-term Whig member of the U.S. House of Representatives
- Linda Drane Burdick – chief assistant state attorney at Orange and Osceola County State Attorney's Office in Orlando, Florida; lead prosecutor on State of Florida vs. Casey Anthony case
- Ralph J. Cappy – Justice and Chief Justice of Pennsylvania Supreme Court
- Ben Cardin – U.S. Senator from Maryland
- Johnny Chiang – Taiwanese politician who serves as the Chairman of the Kuomintang, former penultimate minister of the Government Information Office, and member of the Legislative Yuan
- Steven Choi – mayor of Irvine, California
- Earl Chudoff – U.S. Representative
- Robert J. Cindrich – former U.S. attorney and US District judge
- David I. Cleland – engineer and educator; the "Father of Project Management"
- Bill Cobey – former U.S. Representative from North Carolina's 4th congressional district, director of Jesse Helms Center
- Harry W. Colmery – Author of G.I. Bill.
- Robert J. Corbett – Republican member of U.S. House of Representatives from Pennsylvania
- William Corbett – former acting governor of Guam
- Father James Cox – U.S. presidential candidate in 1932 and labor activist
- Adrian Cronauer – disc jockey, attorney, activist, basis for movie Good Morning, Vietnam; helped to found WPGH AM radio station
- Cornelius Darragh – U.S. district attorney for western district of Pennsylvania, abolitionist, Whig member of U.S. House of Representatives
- Harmar D. Denny, Jr. – U.S. Representative
- Eugene A. DePasquale – Pennsylvania Auditor General
- Patrick R. Donahoe – Postmaster General
- James H. Duff – Pennsylvania Governor, U.S. Senator
- Charlene Dukes – first vice chair of the Maryland Democratic Party
- Harry Allison Estep – U.S. Representative
- Lucy Fato – corporate attorney, Executive Vice President & General Counsel for Seaport Entertainment Group
- Tom Feeney – U.S. representative
- Jay Fisette – member of Arlington County, Virginia's Board of Supervisors
- David Frederick – appellate attorney who has argued more than 50 cases before the Supreme Court of the United States
- George W. Guthrie – Mayor of Pittsburgh, 1906–1909; Ambassador to Japan
- Melissa Hart – U.S. Representative, 2001–2007
- Orrin Hatch – U.S. Senator, 1976-2018
- David J. Hickton – staff director and senior counsel to the House Select Subcommittee on the Coronavirus Crisis, former U.S. Attorney for the Western District of Pennsylvania, director and founder of the University of Pittsburgh Institute for Cyber Law, Policy and Security
- Janice M. Holder – first woman Chief Justice of Tennessee
- Mark R. Hornak – Judge for U.S. District Court
- Frank Houben – Dutch provincial governor
- Peter Huang – political activist and failed assassin
- K. Leroy Irvis – Speaker of the Pennsylvania House of Representatives; first African American Speaker of the House of any U.S. state legislature since reconstruction
- William W. Irwin – Mayor of Pittsburgh and Whig member of U.S. House of Representatives
- Mahmoud Jibril – head of executive team of newly formed National Transitional Council of Libyan Republic
- Judith Krug – librarian and anti-censorship activist who co-founded Banned Books Week
- William Lerach – securities class-action lawyer; leading attorney in corporate and securities litigation cases including Enron, WorldCom and AOL/Time Warner
- Roslyn Litman, who successfully sued the NBA on behalf of blackballed player Connie Hawkins.
- Roozbeh Aliabadi – advisor to Ministry of Foreign Affairs in Iran and political commentator
- Walter H. Lowrie – chief justice of state Supreme Court
- Wangari Maathai – 2004 Nobel Peace Prize winner
- Christopher Lyman Magee – powerful 19th-century Pittsburgh political boss
- Wilson McCandless – federal judge and candidate for Democratic nomination for President of the United States
- Jonas R. McClintock - 8th mayor of Pittsburgh, Pennsylvania
- Samuel J. R. McMillan – Republican U.S. Senator from Minnesota
- Andrew W. Mellon – longest-serving U.S. Secretary of the Treasury, banker, philanthropist
- Natalie Mihalek - Republican member of the Pennsylvania House of Representatives
- Dalia Mogahed – Muslim scholar
- Jim Moran – Democratic member of U.S. House of Representatives
- Clayton Morris – co-anchor of Fox and Friends on Fox News Channel
- John Murtha – U.S. representative, 1974–2010
- Susan Richard Nelson – Judge for United States District Court for the District of Minnesota
- Dan Onorato – chief executive of Allegheny County, Pennsylvania and former Democratic nominee for governor
- Vjosa Osmani – Chairwoman of the Assembly of Kosovo, 2020–
- Ralph Pampena – Pittsburgh Police Chief, 1987–1990
- Richard Pan - California State Assemblymember and Senator
- David A. Reed – U.S. Senator
- James Hay Reed – lawyer and U.S. federal judge
- Rick Santorum – U.S. Senator, 1995–2007
- Richard Mellon Scaife – conservative activist, newspaper publisher, philanthropist
- Elmer Eric Schattschneider – political scientist and former president of the American Political Science Association.
- Bud Shuster – Republican member of U.S. House of Representatives
- Richard M. Simpson – Republican member of U.S. House of Representatives
- Edgar Snyder – personal injury attorney
- Jon Soltz – chairman and co-founder of VoteVets.org
- Wilkins F. Tannehill – author, Whig politician, first mayor of Nashville, Tennessee
- Richard Thornburgh – U.S. Attorney General, Governor of Pennsylvania
- Harve Tibbott – Republican member of the United States House of Representatives from Pennsylvania
- Tshering Tobgay – Prime Minister of Bhutan
- Debra Todd – Justice on Pennsylvania Supreme Court
- James A. Traficant Jr. – convicted U.S. representative from Ohio
- Aliyu Wamakko – former governor of Sokoto State in Nigeria
- Mary Jo White - - Pennsylvania State Senator
- William Wilkins – student in Pittsburgh Academy, U.S. Senator ; minister to Russia ; Secretary of War
- James A. Wright – U.S. Representative
- Albert Wynn – Democratic member of U.S. House of Representatives
- Joseph "Chip" Yablonski – attorney, NFL Players Association; son of murdered labor leader Joseph Yablonski
- Young Woo Kang – member of National Council On Disability
- Faith B. Yisrael – member of the Tobago House of Assembly
- Chris Zurawsky – journalist; director of communications and public affairs for Association of American Cancer Institutes; political candidate
Science, medicine, and technology
- Engin Arık – Turkish particle physicist who headed the Experimental High Energy Physics group at the Boğaziçi University
- Harry Bisel – pioneering medical oncologist, founding member of American Association of Clinical Oncology, American Society of Preventative Oncology and American Association for Cancer Education
- Christine L. Borgman – information sciences scholar
- Herbert Boyer – biochemist; 1990 recipient of National Medal of Science; co-founder of Genentech
- Margaret W. "Hap" Brennecke – NASA metallurgist
- Jane A. Cauley – epidemiologist, University of Pittsburgh Cancer Institute
- Jingguang Chen, Chinese-American material scientist
- John Choma – Professor and Chair of Electrical Engineering-Electrophysics at University of Southern California
- Bob Colwell – electrical engineer, chief architect on Pentium Pro, Pentium II, Pentium III, and Pentium 4 microprocessors
- William Hunter Dammond – Noted early African-American civil engineer who developed railway safety systems.
- Sidney Dancoff – theoretical physicist known for Tamm–Dancoff approximation method and for nearly developing renormalization method for solving quantum electrodynamics
- Lee Davenport – physicist responsible for development and deployment of SCR-584 radar system in World War II
- Catherine D. DeAngelis – pediatrician; medical educator; first woman editor-in-chief of Journal of the American Medical Association
- G. Michael Deeb – cardiothoracic surgeon, Herbert Sloan Collegiate Professor of Surgery, and Director of Multidisciplinary Aortic Clinic at University of Michigan Medical Center
- Emilio del Valle Escalante – professor of Latin American/indigenous literature, culture and social movements at University of North Carolina at Chapel Hill
- Bernard Fisher – pioneer breast cancer researcher
- Patrick D. Gallagher – physicist and 14th director of U.S. Department of Commerce's National Institute of Standards and Technology, Chancellor of the University since 2014
- George Otto Gey – scientist who first propagated the HeLa cell line
- Kevin Guskiewicz – sports medicine scholar and MacArthur "Genius" Fellow; among first to identify long-term threats to athletes of multiple concussions
- David Halliday – physicist known for textbooks Physics and Fundamentals of Physics
- Ann M. Hardy – Epidemiologist known for her research in AIDs surveillance and tracking and her expertise in human subject ethics
- Jacob Pieter Den Hartog – Timoshenko Medal winner for distinguished contributions to field of applied mechanics
- Philip Hench – 1950 Nobel Prize co-winner in medicine with Mayo Clinic colleague Dr. Kendall, for work on adrenal cortex hormones
- Norman H Horowitz – geneticist, worked on genome organization and tests for famous one gene-one enzyme hypothesis, space scientist for Mariner and Viking missions to Mars
- Abul Hussam – inventor of Sono arsenic filter
- Theresa J. Kaijage – Tanzanian NGO director and social worker known for HIV research and advocacy
- Rosella Kanarik, American mathematics professor
- William Kelly – metallurgy graduate, industrialist and independent developer of Bessemer process
- Ravindra Khattree – statistician of Fountain-Khattree-Peddada Theorem fame; author and editor
- Charles Glen King – biochemist noted for isolating vitamin C
- Paul Lauterbur – 2003 Nobel Prize winner in medicine for invention of MRI machine
- Benjamin Lee – elementary particle physicist and head of Theoretical Physics Department at Fermi National Accelerator Laboratory
- Bert W. O'Malley – molecular endocrinologist and 2008 National Medal of Science laureate
- Bennet Omalu – pathologist noted for discovery of chronic traumatic encephalopathy in football players while at Pitt
- Peter Pusey – emeritus professor of physics at University of Edinburgh awarded Rhodia Prize for study of dynamically arrested particulate matter
- Joan Redwing - professor of materials science and engineering and electrical engineering at Pennsylvania State University
- Emily Rice – astronomy professor at City University of New York
- Washington Roebling – civil engineer known for work on Brooklyn Bridge
- Michelle Rogan-Finnemore – geologist, legal expert, Antarctic program manager
- John Wistar Simpson – pioneer in nuclear energy; recipient of Edison Medal
- Rebecca Skloot – freelance science writer, author, specializes in science and medicine
- Mary Margaret Speer, American mathematician
- Jesse Leonard Steinfeld – Surgeon General of the United States, 1969–1973
- Lap-chee Tsui – geneticist who identified defective gene that causes cystic fibrosis; president of HUGO, the international organization of scientists involved in Human Genome Project; former Vice-Chancellor of University of Hong Kong
- William E. Wallace – physical chemist and Guggenheim Fellow who worked on Manhattan Project
- Edward J. Wasp – Elmer A. Sperry Award-winning engineer and inventor known for developing long distance slurry pipelines
- Cyril Wecht – forensic pathologist
- John Wheatley – Fritz London Memorial Prize winner known for his research on liquid helium-3
- Jerome Wolken – biophysicist
- Wu Yundong – theoretical organic chemist
- Nancy Zahniser – pharmacologist
- Vladimir Zworykin – inventor, engineer, pioneer of television technology, sometimes called "father of television"
Other
- Dosia Carlson, minister and hymnwriter
- Lisa Mantini, mathematician
- Marie Hochmuth Nichols – influential rhetorical critic
- Charles D. Provan – author of controversial books and articles on Christian topics and holocaust denial
- Harry K. Thaw – murderer and son of coal and railroad baron William Thaw