| Name | Chapter and year | Notability | |
| James Arness | Beloit 1946 | Actor known for portraying Matt Dillon in the Television series Gunsmoke | |
| John Backe | Miami 1954 | President and CEO of CBS | |
| Steve Bellamy | Indiana University 1986 | Entrepreneur in sports and entertainment known for founding several niche cable Television networks | |
| Bruce Bennett | Washington 1928 | Film and television actor who won the silver medal for the shot put at the 1928 Summer Olympics | |
| John Boles | Texas 1917 | Actor | |
| Jackson Bostwick | Alabama 1965 | Actor known for the Television series Shazam! | |
| Kyle Brandt | Princeton 2001 | Television host, media personality, and actor | |
| Thom Brennaman | Ohio 1986 | Television sportscaster | |
| Ned Brower | Southern Methodist 1998 | Drummer and vocalist in the rock quintet Rooney | |
| Phil Brown | Stanford 1937 | Actor | |
| Robert Butler | UCLA 1950 | Emmy Award-winning Television director | |
| Jay Chandrasekhar | Colgate 1990 | Actor and film director | |
| Lloyd Corrigan | UC Berkeley 1922 | Actor who appeared in more than 90 films | |
| John Doman | Pennsylvania 1966 | Actor | |
| Bergen Evans | Miami 1924 | Television personality who won a Peabody Award for excellence in broadcasting | |
| Neil Everett | Willamette 1984 | Anchor of SportsCenter | |
| Chet Forte | Columbia 1957 | Television director known for Monday Night Football | |
| Pat Green | Texas Tech 1995 | Country music artist | |
| Cary Guffey | Florida 1994 | Actor known for Close Encounters of the Third Kind | |
| Leigh Harline | Utah 1929 | Film composer and songwriter; won an Academy Award for Best Original Song in 1940 for "When You Wish Upon a Star" | |
| Kevin Heffernan | Colgate | Actor and a member of the comedy troupe Broken Lizard | |
| Horace Heidt | UC Berkeley 1924 | Pianist, big band leader, and radio and Television personality | |
| Foster Hewitt | Toronto 1925 | Radio broadcaster known for Hockey Night in Canada | |
| Griffin House | Miami 2002 | Singer-songwriter | |
| Chuck Howard | Duke 1955 | Emmy Award-winning producer known for Wide World of Sports | |
| Sidney Howard | UC Berkeley 1912 | Playwright and screenwriter; received a Pulitzer Prize for Drama in 1925 for They Knew What They Wanted and a posthumous Academy Award for Best Adapted Screenplay in 1939 for Gone with the Wind | |
| Jeffrey Jones | Lawrence 1968 | Actor known for Ferris Bueller's Day Off | |
| Richard Karn | Washington 1978 | Actor known for Home Improvement | |
| Burt Kwouk | Bowdoin 1953 | Actor | |
| Steve Lemme | Colgate | Actor and a member of the comedy troupe Broken Lizard | |
| Daniel Lindsay | Missouri 2001 | Filmmaker known for the Oscar-winning sports documentary Undefeated | |
| David Lloyd | Colgate 1983 | Anchor for SportsCenter | |
| Pare Lorentz | West Virginia 1926 | Filmmaker considered to be the father of the modern documentary | |
| David Martin | Yale 1965 | Television correspondent, journalist, and author for CBS News | |
| Walter Massey | MIT 1951 | Actor | |
| Les Mayfield | Southern California 1982 | Film director known for Encino Man and Blue Streak | |
| Max Morath | Colorado College 1947 | Ragtime pianist and songwriter | |
| Edward P. Morgan | Whitman 1932 | Broadcast journalist for ABC, CBS, and PBS; Peabody Award winner in 1956 | |
| William R. Moses | Wesleyan 1982 | Actor known for the 1980s prime-time soap opera Falcon Crest | |
| Kenyon Nicholson | Wabash 1917 | Playwright and screenwriter | |
| Lance Norris | Whitman 1984 | Actor and writer | |
| Frank Pacelli | Illinois 1948 | Emmy Award-winning director known for The Young and the Restless | |
| George Peppard | Purdue 1952 | Actor known for Breakfast at Tiffany's and The A-Team | |
| Robert Pine | Ohio Wesleyan 1963 | Actor known for the television series CHiPs | |
| Robert Reed | Northwestern 1954 | Actor known for The Brady Bunch | |
| David Richmond-Peck | Western Ontario 1996 | Actor who has appeared in over 70 film and Television roles | |
| Rivers Rutherford | Mississippi 1989 | Country music songwriter | |
| Stephen H. Sholes | Rutgers 1933 | Recording executive, producer, and member of the Country Music Hall of Fame | |
| Jeremy Slate | St. Lawrence 1952 | Actor | |
| Stephen Sondheim | Williams 1950 | Composer and lyricist known for Sweeney Todd: The Demon Barber of Fleet Street and West Side Story | |
| Paul Soter | Colgate | Actor and a member of the comedy troupe Broken Lizard | |
| Erik Stolhanske | Colgate 1991 | Actorand a member of the comedy troupe Broken Lizard | |
| Jess Thomas | Nebraska 1948 | Operatic tenor | |
| Erland Van Lidth De Jeude | MIT 1976 | Actor | |
| Doodles Weaver | Stanford 1937 | Character actor, comedian, and musician who hosted The Doodles Weaver Show | |
| Robb Weller | Washington 1972 | Television personality and game show host known for Entertainment Tonight and Win, Lose or Draw | |
| Adam West | Whitman 1951 | Actor known for Batman and Family Guy | |
| Brian J. White | Dartmouth | Actor known for Stomp the Yard | |
| Robert Wilson | Texas 1963 | Playwright, Obie Award winner for direction, and Olivier Award winner for Best New Opera | |
| Christopher Woodrow | Alabama 1999 | Hollywood movie producer known for Birdman, Black Mass, and Hacksaw Ridge | |
| Paul Worley | Vanderbilt 1972 | Record producer who discovered the Dixie Chicks and produced the Grammy Award-winning album Own the Night for Lady Antebellum | |
| Name | Chapter and year | Notability | |
| Theodore C. Achilles | Stanford 1925 | US Ambassador to Peru | |
| Joe Allbaugh | Oklahoma State 1974 | Director of the Federal Emergency Management Agency | |
| John Mills Allen | Cumberland 1869 | US House of Representatives from Mississippi | |
| A. Piatt Andrew | Wabash 1892 | US House of Representatives from Massachusetts | |
| William Hepburn Armstrong | Princeton 1847 | US House of Representatives from Pennsylvania | |
| Owen Aspinall | Denison 1949 | Governor of American Samoa | |
| Wayne N. Aspinall | Denver 1919 | US House of Representatives from Colorado, Colorado House of Representatives, Colorado Senate | |
| Charles Montague Bakewell | California 1889 | US House of Representatives from Connecticut and Connecticut State Senate | |
| George Thomas Barnes | Georgia 1853 | US House of Representatives from Georgia | |
| Lewis O. Barrows | Maine 1916 | Governor of Maine and Secretary of State of Maine | |
| John L. Bates | Boston 1882 | Governor of Massachusetts and Speaker of the Massachusetts House of Representatives | |
| Albert I. Beach | Kansas 1905 | Mayor of Kansas City, Missouri | |
| James Andrew Beall | Texas 1890 | US House of Representatives from Texas | |
| James A. Beaver | Washington and Jefferson 1856 | Governor of Pennsylvania | |
| James T. Begg | Wooster 1903 | US House of Representatives from Ohio | |
| Michael Bennet | Wesleyan 1987 | US Senator from Colorado | |
| Thomas Warren Bennett | DePauw 1855 | US House of Representatives from Idaho and Governor of Idaho Territory | |
| Ami Bera | UC Irvine 1987 | US House of Representatives from California | |
| Albert S. Berry | Miami 1856 | US House of Representatives from Kentucky | |
| Richard W. Blue | Washington and Jefferson 1864 | US House of Representatives from Kansas | |
| Hale Boggs | Tulane 1935 | US House of Representatives from Louisiana | |
| Newton Booth | DePauw 1846 | US Senator from California and Governor of California | |
| William Borah | Kansas 1884 | US Senator from Idaho | |
| Henry Sherman Boutell | Iowa 1873 | US House of Representatives from North Dakota, Minister Plenipotentiary to Portugal, and Minister Plenipotentiary to Switzerland | |
| Emmett Forest Branch | Indiana 1896 | Governor of Indiana | |
| Louis J. Brann | Maine 1898 | Governor of Maine, Maine House of Representatives, and Mayor of Lewiston, Maine | |
| Donald G. Brotzman | Colorado 1943 | US House of Representatives from Colorado, Colorado House of Representatives, and United States Attorney for Colorado | |
| Charles Hillman Brough | Johns Hopkins 1898 | Governor of Arkansas | |
| B. Gratz Brown | Transylvania 1846 | US Senator from Kentucky | |
| John Young Brown | Centre 1855 | US House of Representatives from Kentucky and Governor of Kentucky | |
| Norris Brown | Iowa 1883 | US Senator from Nebraska | |
| Webster E. Brown | Wisconsin 1874 | US House of Representatives from Wisconsin | |
| Henry Augustus Buchtel | DePauw 1872 | Governor of Colorado | |
| George S. Buck | | Mayor of Buffalo, New York | |
| Joseph R. Burton | Hanover 1873 | US Senator from Kansas | |
| John Marshall Butler | Johns Hopkins 1921 | US Senator from Maryland | |
| William D. Bynum | Indiana 1869 | US House of Representatives from Indiana | |
| Jo Byrns | Vanderbilt 1890 | US House of Representatives from Tennessee and Speaker of the US House of Representatives | |
| Courtney W. Campbell | | US House of Representatives from Florida | |
| Ezekial Samuel Candler Jr. | Mississippi 1881 | US House of Representatives from Mississippi | |
| Rush Clark | Washington and Jefferson 1853 | US House of Representatives from Iowa | |
| Frank G. Clarke | Dartmouth 1873 | US House of Representatives from New Hampshire | |
| Cassius Marcellus Clay | | US ambassador to Russia, Kentucky House of Representatives, and Kentucky Senate | |
| Isaac Clements | DePauw 1859 | US House of Representatives from Illinois | |
| John Coburn | Wabash 1846 | United States Representative from Indiana, Associate Justice of Montana Territorial Supreme Court, Secretary of the Territory of Montana, and Brigadier General in the United States Army | |
| Schuyler Colfax | DePauw 1854 | Vice President of the United States, US House of Representatives from Indiana; Speaker of the US House of Representatives | |
| Daniel Webster Comstock | Ohio Wesleyan 1860 | US House of Representatives from Indiana | |
| John Sherman Cooper | Centre 1923 | US Senator from Kentucky; US Ambassador to India, US Ambassador to Nepal, and US Ambassador to West Germany | |
| Norris Henry Cotton | Wesleyan 1923 | US Senator from New Hampshire, US House of Representatives from New Hampshire, and Speaker of the New Hampshire House of Representatives | |
| William S. Cowherd | Missouri 1881 | US House of Representatives from Missouri and Mayor of Kansas City, Missouri | |
| William B. Cravens | Missouri 1893 | US House of Representatives from Arkansas | |
| Thomas T. Crittenden Jr. | Missouri 1882 | Mayor of Kansas City, Missouri | |
| George W. Cromer | Indiana 1882 | US House of Representatives from Indiana | |
| Charles N. Crosby | Western Reserve 1897 | US House of Representatives from Pennsylvania | |
| Enoch Crowder | Missouri 1886 | US Ambassador to Cuba | |
| Lee Cruce | Vanderbilt 1885 | Governor of Oklahoma | |
| William Cumback | DePauw 1853 | US House of Representatives from Indiana and Lieutenant Governor of Indiana | |
| John A. Danaher | Yale 1920 | US Senator from Connecticut, judge of United States Court of Appeals for the District of Columbia Circuit, and Secretary of the State of Connecticut | |
| John E. Davis | North Dakota 1935 | Governor of North Dakota, director of the Defense Civil Preparedness Agency, and North Dakota Senate | |
| Mark L. De Motte | DePauw 1853 | US House of Representatives from Indiana | |
| David Dewhurst | Arizona 1967 | Lieutenant Governor of Texas | |
| Robert Docking | Kansas 1946 | Governor of Kansas and mayor of Kansas City, Missouri | |
| Ozro J. Dodds | Miami 1861 | US House of Representatives from Ohio | |
| Bob Dold | Denison 1991 | US House of Representatives from Illinois | |
| John E. Dolibois | Miami 1942 | US Ambassador to Luxembourg | |
| Chuck Douglas | Wesleyan 1964 | US House of Representatives from New Hampshire and New Hampshire Supreme Court Associate Justice | |
| Adolph Dubs | Beloit 1942 | US Ambassador to Afghanistan | |
| Tony Earl | Michigan State 1958 | Governor of Wisconsin | |
| Harvey J. Eckley | Washington & Jefferson 1868 | Member of Ohio Senate and judge | |
| Alonzo J. Edgerton | Wesleyan 1850 | US Senator from Minnesota, Minnesota Senate, Minnesota House of Representatives, and United States District Court for the District of South Dakota | |
| Paul C. Edmunds | Virginia 1856 | US House of Representatives from Virginia | |
| Samuel Hitt Elbert | Ohio Wesleyan 1854 | Governor of the Colorado Territory, Secretary of the Territory of Colorado, and chief justice of the Colorado Supreme Court | |
| William Elliott | Virginia 1858 | US House of Representatives from South Carolina | |
| Ezekiel John Ellis | Centenary 1859 | US House of Representatives from Louisiana | |
| Robert Ellsworth | Kansas 1946 | US House of Representatives from Kansas, US Permanent Representative to NATO, Deputy Secretary of Defense | |
| Oscar R. Ewing | | 3rd Administrator of the Federal Security Agency, vice-chair of Democratic National Committee, lawyer, social reformer, and one of the main authors of the Fair Deal program | |
| Joseph S. Farland | West Virginia 1938 | US Ambassador to the Dominican Republic, US Ambassador to Panama, US Ambassador to Iran, and US Ambassador to Pakistan | |
| Joseph R. Farrington | Wisconsin 1919 | US House of Representatives from Hawaii Territory district and Hawaii Territorial Senate | |
| Wallace Rider Farrington | Maine 1891 | Governor of the Territory of Hawaii | |
| Charles James Faulkner | VMI 1868 | US Senator from West Virginia | |
| Mark Felt | Idaho 1935 | Associate Director of the FBI; exposed the Nixon administration's corruption as "Deep Throat" | |
| Scott Field | Virginia 1868 | US House of Representatives from Texas | |
| George Benson Fox | Ohio Wesleyan 1861 | Ohio Senate and Ohio General Assembly | |
| David R. Francis | Washington University in St. Louis 1870 | Governor of Missouri, US Secretary of the Interior, US Ambassador to Russia, and president of Louisiana Purchase Exposition | |
| Bob Franks | DePauw 1973 | US House of Representatives from New Jersey | |
| William E. Fuller | Iowa 1870 | US House of Representatives from Iowa | |
| Samuel Galloway | Miami 1855 | US House of Representatives from Ohio | |
| Alexander H. Garnjost | | New York State Assembly | |
| Dick Gephardt | Northwestern 1962 | US House of Representatives from Missouri; US House Minority Leader | |
| Jack Geraghty | Washington 1956 | Mayor of Spokane, Washington | |
| John Milton Glover | Washington University in St. Louis 1871 | US House of Representatives from Missouri | |
| Abe Goff | Idaho 1922 | US House of Representatives from Idaho and Idaho Senate | |
| Stephen Goldsmith | Wabash 1968 | Mayor of Indianapolis, Indiana | |
| John B. Gordon | Georgia 1854 | US Senator from Georgia, Governor of Georgia, and major general in the Confederate States Army | |
| Howard Mason Gore | | Governor of West Virginia and United States Secretary of Agriculture, and West Virginia Commissioner of Agriculture | |
| Miles T. Granger | Wesleyan 1842 | US House of Representatives from Connecticut | |
| Levi T. Griffin | Michigan 1857 | US House of Representatives from Michigan | |
| George Blackmore Guild | Cumberland 1855 | Mayor of Nashville, Tennessee | |
| Steve Gunderson | Wisconsin 1973 | US House Representative from Wisconsin | |
| Fred L. Hadsel | | US Ambassador to Somalia and US Ambassador to Ghana | |
| William T. Haines | Maine 1876 | Governor of Maine | |
| H. R. Haldeman | UCLA 1948 | White House Chief of Staff; convicted Watergate scandal conspirator | |
| Benton Jay Hall | Miami 1855 | US House of Representatives from Iowa | |
| Charles A. Halleck | Indiana 1922 | US House of Representatives from Indiana | |
| John Hanna | DePauw 1858 | US House of Representatives from Indiana | |
| Mike Harcourt | British Columbia 1963 | Premier of British Columbia and mayor of Vancouver | |
| Charles Henry Hardin | Miami 1841 | Governor of Missouri | |
| James Harlan | DePauw 1845 | US Senator from Iowa; United States Secretary of the Interior | |
| Henry R. Harris | Emory 1847 | US House of Representatives from Georgia | |
| Louis P. Harvey | Western Reserve 1840 | Governor of Wisconsin | |
| Mark Hatfield | Willamette 1943 | US Senator and Governor of Oregon | |
| Joe Heck | Penn State 1984 | US House of Representatives from Nevada | |
| Pat Henry | Mississippi 1882 | US House of Representatives from Mississippi | |
| Robert R. Hitt | DePauw 1855 | US House of Representatives from Illinois | |
| George Hoadly | Western Reserve 1844 | Governor of California and US House of Representatives from California | |
| Henry William Hoffman | Washington and Jefferson 1846 | US House of Representatives from Maryland | |
| Glen Holden Sr. | Oregon 1951 | US Ambassador to Jamaica | |
| Edward E. Holland | Richmond 1879 | US House of Representatives from Virginia | |
| Linwood Holton | W&L 1945 | Governor of Virginia | |
| Stanley Hornbeck | Colorado 1903 | US Ambassador to the Netherlands | |
| Jonas G. Howard | DePauw 1847 | US House of Representatives from Indiana | |
| Frank N. Ikard | Texas 1932 | US House Representative from Texas | |
| Clifford C. Ireland | Knox 1901 | US House of Representatives from Illinois | |
| James F. Izlar | Emory 1855 | US House of Representatives from South Carolina | |
| Craig James | Florida 1963 | US House of Representatives from Florida | |
| William Marion Jardine | Kansas State 1894 | US Secretary of Agriculture, US Ambassador to Egypt, president of Kansas State Agricultural College, and Kansas State Treasurer | |
| Eric M. Javits | Columbia 1952 | Ambassador to the Organisation for the Prohibition of Chemical Weapons | |
| Leslie Jensen | South Dakota | Governor of South Dakota | |
| Martin N. Johnson | Iowa 1873 | US Senator from North Dakota | |
| Brereton C. Jones | Virginia 1961 | Governor of Kentucky, Lieutenant Governor of Kentucky, and West Virginia House of Delegates | |
| Doug Jones | Alabama 1976 | US Senator from Alabama | |
| David Karnes | Nebraska 1971 | US Senator from Nebraska | |
| James P. Kem | Missouri 1910 | US Senator from Missouri | |
| William E. Kemp | Missouri 1914 | Mayor of Kansas City, Missouri | |
| Peter Kinder | Missouri 1976 | Lieutenant Governor of Missouri | |
| William M. Kinsey | Monmouth 1869 | US Representative from Missouri | |
| William F. Kopp | Iowa Wesleyan 1892 | US Representative from Iowa | |
| Edward H. Kruse | Indiana 1940 | US Representative from Indiana | |
| Bruce Kyle | | Florida House of Representatives | |
| Robert M. La Follette Jr. | Wisconsin 1917 | US Senator from Wisconsin and Governor of Wisconsin | |
| Charles B. Landis | Wabash 1883 | US Representative from Indiana | |
| Milton Latham | Jefferson 1843 | US Senator from California and Governor of California | |
| John J. Lentz | Wooster 1881 | US Representative from Ohio | |
| Fred D. Letts | Iowa 1899 | US Representative from Iowa | |
| David Linton | Miami 1839 | Ohio State Senator; co-founder of Beta Theta Pi | |
| Tom Loeffler | Texas 1971 | US House Representative from Texas | |
| Frank O. Lowden | Iowa 1885 | US House Representative from Illinois and Governor of Illinois | |
| Richard Lugar | Denison 1954 | US Senator from Indiana and Mayor of Indianapolis, Indiana | |
| Ray Mabus | Mississippi 1969 | Governor of Mississippi, US Ambassador to Saudi Arabia, and Secretary of the Navy | |
| Humphrey Marshall | Transylvania 1845 | US House of Representatives from Kentucky and US Minister to China | |
| Roger Marshall | Kansas State 1984 | US Senator from Kansas | |
| James G. Martin | Davidson 1957 | US House of Representatives and Governor of North Carolina | |
| Henry M. Mathews | West Virginia 1857 | Governor of West Virginia | |
| Courtland C. Matson | DePauw 1862 | US House of Representatives from Indiana | |
| Stanley Matthews | Cincinnati 1842 | US Senator from Ohio; US Supreme Court Justice | |
| John J. McCloy | Amherst 1916 | United States Assistant Secretary of War and presidential advisor | |
| James L. McConaughy | Yale 1909 | Governor of Connecticut and Lieutenant Governor of Connecticut | |
| John W. McCormick | Ohio 1855 | US House of Representatives from Ohio | |
| James W. McDill | Miami 1853 | US House of Representatives from Iowa | |
| Joseph E. McDonald | DePauw 1849 | US Senator from Indiana | |
| David McKinley | Purdue 1969 | US House of Representatives from West Virginia, member of West Virginia House of Delegates | |
| William P. McLean | North Carolina 1857 | US House of Representatives from Texas | |
| William H. McMaster | Beloit 1899 | US Senator from South Dakota and Governor of South Dakota | |
| Paul V. McNutt | Indiana 1913 | Governor of Indiana and first US Ambassador to the Philippines | |
| Robert W. Miers | Indiana 1870 | US House of Representatives from Indiana | |
| Andrew Jackson Montague | Richmond 1882 | US House of Representatives from Virginia and Governor of Virginia | |
| J. Waldo Monteith | Toronto 1927 | Member of the House of Commons of Canada | |
| Arch A. Moore Jr. | West Virginia 1951 | Governor of West Virginia and US House of Representatives from West Virginia | |
| Dwight Morrow | Amherst 1895 | Senator from New Jersey and US Ambassador to Mexico | |
| Oliver P. Morton | Miami 1847 | Governor of Indiana | |
| David C. Mulford | Lawrence 1959 | US Ambassador to India | |
| John Mutz | Northwestern 1957 | Lieutenant Governor of Indiana and President of Lilly Endowment | |
| Albinus Nance | Knox 1868 | Governor of Nebraska | |
| Bill Nelson | Yale 1964 | US House of Representatives from Florida, US Senator from Florida, State Treasurer of Florida; | |
| John Stoughton Newberry | Michigan 1847 | US House of Representatives from Michigan | |
| Dick Nichols | Kansas State 1951 | US House of Representatives from Kansas | |
| Don Nickles | Oklahoma State 1971 | US Senator from Oklahoma | |
| John W. Noble | Miami 1850 | US Secretary of the Interior | |
| Jeremiah E. O'Connell | Boston 1906 | US House of Representatives from Rhode Island and justice of Rhode Island Supreme Court | |
| Benjamin Odell | Bethany 1877 | US House of Representatives from New York | |
| Richard B. Ogilvie | Yale 1945 | Governor of Illinois | |
| Alvin M. Owsley | Texas 1912 | US Ambassador to Romania | |
| Bob Packwood | Willamette 1954 | US Senator from Oregon | |
| Halbert E. Paine | Western Reserve 1845 | US House of Representatives from Wisconsin | |
| Guy Brasfield Park | Missouri 1896 | Governor of Missouri | |
| Richard Cunningham Patterson Jr. | Nebraska 1909 | US Ambassador to Yugoslavia, US Ambassador to Guatemala, and US Minister to Switzerland, vice-president and director of the National Broadcasting Co., and chairman of RKO Corp. | |
| John M. Pattison | Ohio Wesleyan 1869 | US House of Representatives from Ohio and Governor of Ohio | |
| George Smith Patton | VMI 1877 | Mayor of San Marino, California and father of General George S. Patton | |
| James Paull | | West Virginia Senate | |
| Boies Penrose | Harvard 1881 | US Senator from Pennsylvania | |
| William J. Perry | Carnegie Mellon 1949 | US Secretary of Defense | |
| David Peterson | Western Ontario 1966 | Premier of Ontario | |
| Walter R. Peterson Jr. | Dartmouth 1947 | Governor of New Hampshire | |
| Bill Phelps | Missouri 1956 | US House of Representatives from Missouri | |
| Robert H. Phinny | North Carolina 1945 | US Ambassador to Swaziland | |
| Michael Pitfield | St. Lawrence 1956 | Canadian Senator | |
| Henry Moses Pollard | Dartmouth 1857 | US House of Representatives from Missouri | |
| John G. Pollard | Richmond 1891 | Governor of Virginia | |
| Laurence Pope | Bowdoin 1967 | US Ambassador to Chad | |
| Andrew Jackson Poppleton | Michigan 1851 | Mayor of Omaha, Nebraska | |
| Albert G. Porter | DePauw 1843 | Governor of Indiana; US House of Representatives from Indiana; and US Minister to Italy | |
| George M. Pritchard | North Carolina 1907 | US House of Representatives from North Carolina | |
| Jacob J. Pugsley | Miami | US House of Representatives from Ohio | |
| Matthew Quay | Jefferson 1850 | US Senator from Pennsylvania | |
| Saul Rae | Texas 1936 | Canadian Ambassador to the United Nations, Canadian Ambassador to Mexico, Canadian Ambassador to Guatemala and the Netherlands | |
| Joseph L. Rawlins | Indiana 1874 | US Senator from Utah | |
| John H. Ray | Minnesota 1908 | US House of Representatives from New York | |
| Henry Augustus Reeves | Michigan 1852 | US House of Representatives from Michigan | |
| Robert R. Reynolds | North Carolina 1906 | US Senator from North Carolina | |
| John Jacob Rhodes | Kansas State 1938 | US House of Representatives from Arizona; US House Minority Leader | |
| Robert G. Rich Jr. | Florida 1952 | US Ambassador to Belize | |
| Ira E. Rider | St. Lawrence 1888 | US House of Representatives from New York | |
| Richard O. Ristine | Wabash 1941 | Lieutenant Governor of Indiana and Indiana Senate | |
| William Alfred Robinson | Toronto 1925 | Member of the Canadian House of Commons | |
| Charlie Rose | Davidson 1961 | US House of Representatives from North Carolina | |
| Arthur B. Rouse | Hanover 1896 | US House of Representatives from Kentucky | |
| Thomas L. Rubey | Missouri 1885 | US House of Representatives from Missouri | |
| Eugene P. Ruehlmann | Cincinnati 1947 | Mayor of Cincinnati, Ohio | |
| Aimaro Satō | DePauw 1881 | Japanese Ambassador to the United States | |
| Jake Sawatzky | British Columbia 2024 | Member of the Canadian House of Commons | |
| Daniel Schaefer | South Dakota 1958 | US House of Representatives from Colorado | |
| Charles Frederick Scott | Kansas 1881 | US House of Representatives from Kansas and Kansas State Senator | |
| Harvey D. Scott | DePauw 1850 | US House of Representatives from Indiana | |
| Townsend Scudder | Columbia 1888 | US House of Representatives from New York | |
| Fred A. Seaton | Kansas State 1931 | US Secretary of the Interior, US Senator from Nebraska, and Assistant Secretary of Defense | |
| Philip Sharp | DePauw 1964 | US House of Representatives from Indiana | |
| David Sholtz | Yale 1914 | Governor of Florida | |
| Scott Sifton | Truman State 1996 | Member of the Missouri Senate | |
| George G. Siebels Jr. | Virginia 1937 | Mayor of Birmingham, Alabama | |
| Arnold Smith | Toronto 1935 | Canadian Ambassador to Egypt the USSR | |
| Denny Smith | Willamette 1960 | US House of Representatives from Oregon | |
| Frank Ellis Smith | Mississippi 1941 | US House of Representatives from Mississippi | |
| John M. C. Smith | Michigan 1881 | US House of Representatives from Michigan | |
| Bertrand Snell | Amherst 1894 | US House of Representatives from New York | |
| Earl Snell | Oregon 1907 | Governor of Oregon | |
| Charles Wilbert Snow | Bowdoin 1907 | Governor of Connecticut | |
| Zack Space | Kenyon 1983 | US House of Representatives from Ohio | |
| William B. Spencer | Centenary 1855 | US House of Representatives from Louisiana | |
| John Spratt | Davidson 1964 | US House of Representatives from South Carolina | |
| William McKendree Springer | Indiana 1857 | US House of Representatives from Illinois | |
| William Francis Stevenson | Davidson 1885 | US House of Representatives from South Carolina | |
| Kevin Stitt | Oklahoma State 1995 | Governor of Oklahoma | |
| Edward C. Stokes | Brown 1883 | Governor of New Jersey | |
| Reginald H. Sullivan | Wabash 1897 | Mayor of Indianapolis, Indiana | |
| Howard Sutherland | Westminster 1889 | US Senator from West Virginia | |
| Robert Franklin Sutherland | Toronto 1911 | Member of the Canadian House of Commons | |
| Mike Synar | Oklahoma 1972 | US House Representative from Oklahoma | |
| Charles Phelps Taft II | Yale 1918 | Governor of Ohio and Mayor of Cincinnati, Ohio | |
| Leon Rutherford Taylor | Denison 1907 | Governor of New Jersey | |
| Charles M. Teague | | US House of Representatives for California | |
| Hosea Townsend | Western Reserve 1864 | US House of Representatives from Colorado | |
| Henry St. George Tucker III | W&L 1875 | US House of Representatives from Virginia | |
| John Turner | British Columbia 1952 | Prime Minister of Canada | |
| Al Ullman | Whitman 1935 | US House of Representatives from Oregon | |
| William H. Upson | Western Reserve 1842 | US House of Representatives from Ohio | |
| Daniel W. Voorhees | DePauw 1849 | US Senator from Indiana | |
| Durbin Ward | Miami 1843 | Member of the Kentucky General Assembly and brevet brigadier general during the Civil War | |
| George B. Ward | Cumberland 1887 | Mayor of Birmingham, Alabama | |
| John H. Ware III | | US House of Representatives from Pennsylvania and Pennsylvania State Senate | |
| John Warner | W&L 1950 | Secretary of the Navy; US Senator from Virginia; namesake of the attack submarine | |
| Albert Henry Washburn | | American Envoy Extraordinary and US Minister to Austria | |
| Walter A. Watson | Hampden-Sydney 1887 | US House of Representatives from Virginia and Virginia Senate | |
| Claude Weaver | Texas 1887 | US House of Representatives from Oklahoma | |
| Ed Weber | Denison 1953 | US House of Representatives from Ohio | |
| Tom Wheeler | Ohio State 1968 | Chairman of the Federal Communications Commission | |
| Kenneth S. Wherry | Nebraska 1914 | US Senator and Senate Minority Leader, Nebraska Senate | |
| William F. Whiting | Amherst 1886 | US Secretary of Commerce | |
| Jamie Whitten | Mississippi 1933 | US House of Representatives from Mississippi | |
| Ben M. Williamson | Bethany 1886 | US Senator from Kentucky | |
| Wendell Willkie | Indiana 1916 | 1940 Republican Party nominee for President of the United States and member of Indiana House of Representatives | |
| Charles Erwin Wilson | Carnegie 1909 | US Secretary of Defense | |
| Joseph G. Wilson | Miami 1846 | US House of Representatives from Oregon | |
| Charles E. Winter | Iowa Wesleyan 1892 | US House of Representatives from Wyoming; acting Governor of Puerto Rico | |
| Bill Wirtz | Beloit 1933 | US Secretary of Labor | |
| John Sergeant Wise | Virginia 1867 | US House of Representatives from Virginia and United States Attorney for the Eastern District of Virginia | |
| Josiah O. Wolcott | Wesleyan 1901 | US Senator from Delaware, chief justice of the Delaware Supreme Court, and Attorney General of Delaware | |
| Wendell Wyatt | Oregon 1939 | US House of Representatives from Oregon | |
| J. Smith Young | Centenary 1855 | US House of Representatives from Louisiana | |
| Philip Young | St. Lawrence 1931 | US Ambassador to the Netherlands | |
| Eugene M. Zuckert | Yale 1933 | United States Secretary of the Air Force | |
| Name | Chapter and year | Notability | |
| Fred Ahern | Bowdoin 1974 | NHL player with the California Seals, Cleveland Barons, and Colorado Rockies | |
| Ethan Allen | Cincinnati 1926 | Major League Baseball player; head baseball coach at Yale University | - |
| Frank Baumholtz | Ohio 1941 | Professional basketball player and Major League Baseball player | |
| Matty Bell | Centre 1920 | College football player, college football coach, and athletic administrator | |
| Jim Benepe | Northwestern 1986 | Professional golfer | |
| Earl Blaik | Miami 1918 | Head football coach at Dartmouth College and the United States Military Academy | |
| Carl Blaurock | Colorado Mines 1916 | Mountaineer, first American to climb all mountains over 14,000 feet in the continental US | |
| Joe Bottom | Southern California 1977 | 1976 Summer Olympics silver medalist in 100m butterfly strokey | |
| Don Bragg | UCLA 1959 | 1960 Summer Olympics gold medalist in pole vault | |
| Evan Brown | SMU 2017 | Center for the New York Giants, Cleveland Browns, and Detroit Lions | |
| Mike Brown | Dartmouth 1957 | President and general manager of the Cincinnati Bengals | |
| Dave Brundage | Oregon State 1986 | Minor League Baseball player and coach | |
| Jim Brunzell | Minnesota 1971 | Professional wrestler and co-author of the Killer Bees comic book series | |
| George Buehler | Stanford 1969 | Professional football player with the Los Angeles Raiders | |
| John Bunn | Kansas 1920 | Key contributor to the game of basketball | |
| Guy Chamberlin | Nebraska 1916 | College and pro football Hall of Famer: 5x NFL champion | |
| Pete Cipollone | California 1994 | 2004 Summer Olympics gold medalist, rowing | |
| Bob Clotworthy | Ohio State 1954 | 1952 Summer Olympics silver medalist and 1956 Summer Olympics gold medalist in springboard diving | |
| Roy Cochran | Indiana 1941 | 1948 Summer Olympics gold medalist, 400m hurdles, 4 × 400 m relay | |
| Ron Coder | Penn State 1976 | Professional football player with Seattle Seahawks | |
| Don Cohan | Amherst 1951 | 1972 Summer Olympics bronze medalist, sailing | |
| Eddie Collins | Columbia 1907 | Major League Baseball Hall of Famer with the Philadelphia Athletics and the Chicago White Sox, won Six World Series. World Series MVP in 1924. | |
| Don Coryell | Washington 1947 | Coach of the San Diego Chargers | |
| Mel Counts | Oregon State 1964 | Professional basketball player who won two NBA titles with the Boston Celtics; Olympic gold medalist in basketball, 1964 | |
| Edgar Diddle | Centre 1919 | Basketball coach at Western Kentucky University; first coach to win 1,000 games at one school | |
| DeLoss Dodds | Kansas State 1959 | University of Texas at Austin athletic director | |
| Charles Doe | Stanford 1920 | 1920 Summer Olympics and 1924 Summer Olympics gold medalist, rugby | |
| Bobby Douglass | Kansas 1969 | Professional football player with the Chicago Bears | |
| Eddie Eagan | Denver 1920 | 1920 Summer Olympics gold medalist, boxing 178-lb and 1932 Winter Olympics gold medalist in bobsledding | |
| Keith Fahnhorst | Minnesota 1974 | Professional football player with San Francisco 49ers, Super Bowl XVI & XIX Champion | |
| Max Falkenstien | Kansas 1947 | Kansas Jayhawks radio announcer | |
| John Ferris | Stanford 1971 | 1968 Summer Olympics bronze medalist in the 200M and 200 butterfly stroke | |
| Jay Fiedler | Dartmouth 1994 | Professional football player with the Miami Dolphins | |
| Dow Finsterwald | Ohio 1952 | Professional golfer | |
| Jeff Float | Southern California 1983 | 1984 Summer Olympics bronze medalist, 4x200 freestyle relay | |
| Travis Ford | Missouri 1991 | Head basketball coach for Oklahoma State University | |
| Ken Forsch | Oregon State 1969 | Major League Baseball; two-time All-Star team selection; pitched a no-hitter on 7 April 1979 | |
| Bruce Furniss | Southern California 1979 | 1976 Summer Olympics gold medalist, 4x200 freestyle relay and 200 freestyle swimming | |
| Steve Furniss | Southern California 1975 | 1972 Summer Olympics bronze medalist, 200 IM swimming | |
| Dave Gagnon | Colgate 1991 | Professional hockey player with the Detroit Red Wings | |
| George Glamack | North Carolina early 1940s | All American basketball with the NBL, Rookie of the Year 1942 | |
| Iñaki Gómez | British Columbia 2010 | 2012 Summer Olympics Canadian team member, race walking | |
| Gail Goodrich | UCLA 1965 | Professional basketball player with the Los Angeles Lakers | |
| Dan Greenbaum | Southern California 1992 | 1992 Summer Olympics bronze medalist, volleyball | |
| Dan Guerrero | UCLA 1974 | UCLA Bruins athletic director | |
| Ed Hamm | Georgia Tech 1928 | 1928 Summer Olympics gold medalist, long jump | |
| George Harrison | Stanford 1961 | 1960 Summer Olympics gold medalist, 4x200 freestyle relay | |
| Dick Harter | North Carolina 1952 | NBA coach; first head coach for the Charlotte Hornets | |
| Homer Hazel | Rutgers 1925 | Football player and coach | |
| Alan Helffrich | Penn State 1925 | 1924 Summer Olympics gold medalist, relay | |
| Bob Higgins | Penn State 1918 | Professional football player and college football coach | |
| Mark Jerue | Washington 1982 | Professional football player with the New York Jets | |
| Brian Job | Stanford | 1968 Summer Olympics bronze medalist, 200m breaststroke | |
| Brandt Jobe | UCLA 1989 | Professional golfer | |
| Grier Jones | Oklahoma State 1968 | Professional golfer | |
| Charlie Justice | North Carolina 1950 | Professional football player with the Washington Redskins; three-time All-American | |
| Robert Kane | Cornell 1934 | President of the US Olympic Committee | |
| Jeff Kemp | Dartmouth 1981 | Professional football player with the Los Angeles Rams for 5 seasons. | |
| Shahid Khan | Illinois 1971 | Owner of the Jacksonville Jaguars | |
| Johnny Kitzmiller | Oregon 1930 | College and professional football player with the New York Giants | |
| William Koch | MIT 1962 | 1992 America's Cup winner | |
| George Kojac | Rutgers 1931 | 1928 Summer Olympics gold medalist, 100 backstroke, 4x200 relay | |
| Ryan Kuehl | Virginia 1995 | Professional football player | |
| Cawood Ledford | Centre College | University of Kentucky basketball commentator | |
| David Lipsky | Northwestern University | Professional golfer | |
| Jerry Lucas | Ohio State 1962 | Professional basketball player player, college basketball coach, 1960 Summer Olympics gold medalist, basketball | |
| Larry MacPhail | Beloit 1910 | Club president and general manager with the Cincinnati Reds, Brooklyn Dodgers, and New York Yankees | |
| Jim Mandich | Michigan 1970 | Professional football player with Miami Dolphins | |
| Steve Marino | UVA 2002 | Professional golfer | |
| Kent Massey | Oklahoma 1974 | 1996 Summer Olympics bronze medalist, sailing | |
| Scott McCarron | UCLA 1989 | Professional golfer | |
| Charles McGinnis | Wisconsin 1927 | 1928 Summer Olympics bronze medalist, pole vault | |
| Bo McMillan | Centre 1922 | Football player and coach | |
| John Lester Miller | Yale 1924 | 1924 Summer Olympics gold medalist, rowing | |
| Matt Monger | Oklahoma State 1984 | Professional football player with the Buffalo Bills in the Super Bowl XXV | |
| Ray Morrison | Vanderbilt 1912 | Head football coach at Southern Methodist University, Vanderbilt University, Temple University, and Austin College | |
| Dave Mauer | Denison 1954 | Football player, college football coach, and athletic administrator | |
| Lowell North | UC Berkeley 1971 | 1964 Summer Olympics bronze medalist, yachting; 1968 Summer Olympics gold medalist, yachting | |
| Pat O'Dea | Wisconsin 1900 | Australian rules and American football player and coach | |
| John Orsi | Colgate 1932 | Football player and coach | |
| Gus Otto | Missouri 1965 | Professional football player with the Oakland Raiders | |
| John Parker | Stanford 1970 | 1972 Summer Olympics bronze medalist, water polo | |
| Bob Pearce | Oklahoma 1931 | 1932 Summer Olympics gold medalist, wrestling 128-lb | |
| Pete Pihos | Indiana 1945 | Professional football player with the Philadelphia Eagles | |
| Pat Powers | Southern California 1980 | 1984 Summer Olympics gold medalist, volleyball | |
| Chip Reese | Dartmouth 1973 | Professional poker player | |
| Ed Rimkus | St. Lawrence 1937 | 1948 Winter Olympics gold medalist, bobsledding | |
| Jamey Rootes | Clemson 1988 | Major League Soccer general manager, Columbus Crew and Houston Texans | |
| Murray Rose | Southern California 1961 | 1956 Summer Olympics gold medalist in 400 freestyle swimming, 4x200 relay, and 1500 freestyle; 1960 Summer Olympics silver medalist for 1500 freestyle, and bronze medalist for 4x200 relay | |
| Ed Roski Jr. | Southern California 1962 | Owner Los Angeles Kings hockey team | |
| Dick Roth | Stanford 1969 | 1964 Summer Olympics gold medalist, 400 IM swimming | |
| Harlow Rothert | Stanford 1930 | 1932 Summer Olympics silver medalist, shot put | |
| Mike Schmidt | Ohio 1971 | Major League Baseball player; hit 548 home runs; member of the Baseball Hall of Fame | |
| John Shadden | Southern California 1987 | 1988 Summer Olympics bronze medalist, yachting | |
| Gary Sheerer | Stanford 1968 | 1972 Summer Olympics bronze medalist, water polo | |
| Dave Shula | Texas 1973 | Head coach of the Cincinnati Bengals | |
| Jerry Sichting | Purdue 1979 | NBA coach | |
| Stan Smith | Southern California 1969 | Professional tennis player; winner of the 1977 US Open – Men's singles and the 1972 Wimbledon Championships – Men's singles | |
| Bill Sprackling | Brown 1912 | College Football Hall of Fame | |
| Bob Stein | Minnesota 1969 | Professional football player with the Kansas City Chiefs | |
| Mal Stevens | Yale 1924 | Football player and coach | |
| Kevin Still | UCLA 1982 | 1984 Summer Olympics bronze medalist, rowing coxed-pairs | |
| Bill Stoneman | Idaho 1966 | General manager of the Los Angeles Angels; Major League Baseball player | |
| John Tavener | Indiana 1944 | College football player | |
| William G. Thompson | UC Berkeley 1929 | 1928 Summer Olympics gold medalist, rowing eight oars | |
| Bill Veeck | Kenyon 1936 | Major League Baseball franchise owner; Hall of Fame member | |
| Rick Volk | Michigan 1967 | Professional football player with the Miami Dolphins | |
| Ben Wilson | Heidelberg 1944 | Head football coach at Wichita State University | |
| John Wooden | Purdue 1932 | Head basketball coach at UCLA | |