Lactaldehyde dehydrogenase


In enzymology, lactaldehyde dehydrogenase is an enzyme that catalyzes the chemical reaction
The three substrates of this enzyme are -lactaldehyde, oxidised nicotinamide adenine dinucleotide, and water. Its products are -lactic acid, reduced NADH, and a proton.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is -lactaldehyde:NAD+ oxidoreductase. Other names in common use include L-lactaldehyde:NAD+ oxidoreductase, and nicotinamide adenine dinucleotide -linked dehydrogenase. This enzyme participates in pyruvate metabolism.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes,,, and.