Keratoderma

Keratoderma is a local or general thickening of the horny layer of the epidermis.

Classification

The keratodermas are classified into the following subgroups:

Congenital

Simple keratodermas
* Diffuse palmoplantar keratodermas
** Diffuse epidermolytic palmoplantar keratoderma
** Diffuse nonepidermolytic palmoplantar keratoderma
** mal de Meleda
* Focal palmoplantar keratoderma
** Striate palmoplantar keratoderma
* Punctate palmoplantar keratoderma
** Keratosis punctata palmaris et plantaris
** Spiny keratoderma
** Focal acral hyperkeratosis
Complex keratodermas
* Diffuse palmoplantar keratoderma
** Erythrokeratodermia variabilis
** Palmoplantar keratoderma of Sybert
** Olmsted syndrome
** Naegeli–Franceschetti–Jadassohn syndrome
* Focal palmoplantar keratoderma
** Papillon–Lefèvre syndrome
** Pachyonychia congenita type I
** Pachyonychia congenita type II
** Focal palmoplantar keratoderma with oral mucosal hyperkeratosis
** Camisa disease
* Ectodermal dysplasias
** Clouston's hidrotic ectodermal dysplasia
** Acrokeratotic poikiloderma
** Dermatopathic pigmentosa reticularis
* Syndromic keratodermas
** Vohwinkel syndrome
** Palmoplantar keratoderma associated with esophageal cancer
** Palmoplantar keratoderma and spastic paraplegia
** Naxos disease
** Striate palmoplantar keratoderma, woolly hair, and left ventricular dilated cardiomyopathy
** Keratitis-ichthyosis-deafness syndrome
** Corneodermatosseous syndrome
** Huriez syndrome
** Oculocutaneous tyrosinemia
** Cardiofaciocutaneous syndrome
** Schöpf–Schulz–Passarge syndrome
Acquired
Acquired keratodermas
* AIDS-associated keratoderma
* Arsenical keratoses
* Calluses
* Climacteric keratoderma
* Clavi
* Eczema
* Human papillomavirus
* Keratoderma blenorrhagicum
* Lichen planus
* Norwegian scabies
* Paraneoplastic keratoderma
* Psoriasis
* Reactive arthritis
* Secondary syphilis
* Tinea pedis
* Sézary syndrome
* Tuberculosis verrucosa cutis
* Drug-induced keratoderma