Iltovirus


Iltovirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Alphaherpesvirinae. Birds, galliform birds, psittacine birds, chickens, turkeys, and quail serve as natural hosts. Diseases associated with this genus include: acute respiratory diseases: gaHV-1: infectious laryngotracheitis; psHV-1: Pacheco's disease.

Species

The genus consists of the following species:Iltovirus cacatuidalpha2Iltovirus gallidalpha1, also called Gallid alphaherpesvirus 1Iltovirus psittacidalpha1, also called Psittacid alphaherpesvirus 1

Structure

Viruses in Iltovirus are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. The diameter is around 120-200 nm. Genomes are linear and non-segmented, around 150kb in length.
GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
IltovirusSpherical pleomorphicT=16EnvelopedLinearMonopartite

Life cycle

Viral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachment of the viral gB, gC, gD and gH proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear egress, and budding. Birds, galliform birds, psittacine birds, chickens, turkeys, and quail serve as the natural host. Transmission routes are contact, contamination, and air borne particles.
GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
IltovirusBirds: galliform: psittacine-Cell receptor endocytosisBuddingNucleusNucleusOral-fecal; aerosol