Frequentist evaluation of group sequential clinical trial designs
Frequentist evaluation of group sequential clinical trial designs is a scholarly work, published in 2007 in ''Statistics in Medicine''. The main subjects of the publication include causal inference, clinical trial, Bayes' theorem, stopping time, frequentist inference, sequential analysis, type I and type II errors, computer science, Bayesian probability, drug metabolism, econometrics, early stopping, statistics, and optimal stopping. AbstractGroup sequential stopping rules are often used as guidelines in the monitoring of clinical trials in order to address the ethical and efficiency issues inherent in human testing of a new treatment or preventive agent for disease.