Aspartate—ammonia ligase
In enzymology, an aspartate—ammonia ligase is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are ATP, L-aspartate, and NH3, whereas its 3 products are AMP, diphosphate, and L-asparagine.
This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-ammonia ligases. The systematic name of this enzyme class is L-aspartate:ammonia ligase . Other names in common use include asparagine synthetase, and L-asparagine synthetase. This enzyme participates in 3 metabolic pathways: alanine and aspartate metabolism, cyanoamino acid metabolism, and nitrogen metabolism.