A Preprocessor for Shotgun Assembly of Large Genomes
A Preprocessor for Shotgun Assembly of Large Genomes is a scholarly work by Arthur L. Delcher, published in 2004 in ''Journal of Computational Biology''. The main subjects of the publication include biology, RNA sequencing, Hybrid genome assembly, reference genome, sequence assembly, shotgun sequencing, computer science, computational biology, K-mer, ribosome, genome, whole genome sequencing, biological sequence, preprocessor, and polyploidy. The authors report on a set of procedures that (1) corrects most of the sequencing errors, (2) changes quality values accordingly, and (3) produces a list of "overlaps," i.e., pairs of reads that plausibly come from overlapping parts of the genome.