40 BC

By place

Roman Republic

• Consuls: Gnaeus Domitius Calvinus and Gaius Asinius Pollio.
• Siege of Perusia: trying a last attempt to break the siege, which fails; Lucius Antonius surrenders to Octavian. His life is spared, but the citizens are executed or sold into slavery. Fulvia flees with her children and is exiled to Sicyon, where she dies of a sudden illness.
• Spring - Quintus Salvidienus Rufus marches to Transalpine Gaul to take command of the eleven legions, after the death of Quintus Fufius Calenus. Octavian divorces Claudia and marries Scribonia, a sister of Lucius Scribonius Libo and a follower of Sextus.
• May - Gaius Claudius Marcellus, a distinguished member of the Claudii, dies. He leaves Octavia the Younger widowed. She will later marry Mark Antony.
• Sextus Pompey dispatches Menas with four legions and captures Sardinia, driving out Octavian's governor Marcus Lurius. He seizes the capital, Caralis and occupies Corsica. Sextus besieges Cosenza in Bruttium and Thurii in Lucania, ravaging the territory with his cavalry.
• Sextus' fleet raids the ports of Puteoli and Ostia. The populace hold the Triumvirs responsible for prolonging the war, provoking a riot on the Forum. Octavian, with the Praetorian Guard, goes to intercept the riot, and only escapes with his life because Antony summons troops to rescue his junior colleague.
• Treaty of Brundisium: The Triumvirs agrees to divide the Roman Republic into spheres of influence. Gaius Octavian styles himself "Imperator Caesar" and takes control of the Western provinces. Mark Antony is given the Eastern provinces; the River Drin, the boundary between the provinces Illyricum and Macedonia, is to serve as their frontier. Marcus Aemilius Lepidus controls Hispania and Africa. The treaty is cemented by the marriage of Antony and Octavia the Younger.

Asia minor

• Quintus Labienus occupies Cilicia and marches, with an army, into Anatolia. Most cities surrender without resistance, except for Alabanda and Mylasa. The Parthians restore their territory to nearly the limits of the old Achaemenid Empire. Labienus proclaims himself "Parthian Emperor" of Asia Minor.

Egypt

• Mark Antony leaves Alexandria. After receiving news of the outcome at Perusia while en route to Phoenicia, he sets sail for Italy meeting the ambassadors of Sextus Pompey in Athens.

Igodomigodo Kingdom

• Ogiso Igodo dissolves the Ik’edionwere Council. establishes the Royal Council with members of the disbanded Ik’edionwere Council and the Odibo-Ogiso group. He names his combined territories, Igodomigodo with its capital at Ugbekun.

Greece

• Athenodorus, a philosopher, encounters a ghost in Athens. This popular story is one of the first poltergeist stories in history.

Parthia

• Pacorus crosses, with the help of Quintus Labienus, the Euphrates and invades Syria. The capital Antioch surrenders, and the Parthians take Phoenicia and Judea. However, they cannot besiege the fortified city of Tyre, because they have no fleet.
• Parthians conquer Jerusalem. Hyrcanus II is removed from power, while Antigonus the Hasmonean becomes king of Judea under Parthian rule. Herod the Great flees Jerusalem to Rome. There he is titled king of Judea by Mark Antony.

China

• The Ji Jiu Pian dictionary, published about this year during the Han dynasty, is the earliest known reference to the hydraulic-powered trip hammer device.