4-phosphoerythronate dehydrogenase
In enzymology, 4-phosphoerythronate dehydogenase is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are 4-phospho-D-erythronic acid and oxidised nicotinamide adenine dinucleotide. Its products are -3-hydroxy-2-oxo-4-phosphonooxybutanoic acid, reduced NADH, and a proton.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-phospho-D-erythronate:NAD+ 2-oxidoreductase. Other names in common use include PdxB, PdxB 4PE dehydrogenase, and 4-O-phosphoerythronate dehydrogenase. This enzyme participates in vitamin B6 metabolism.