2C-O-4


2C-O-4, also known as 4-isopropoxy-2,5-dimethoxyphenethylamine, is a phenethylamine of the 2C family. It is also a positional isomer of isoproscaline and was probably first synthesized by Alexander Shulgin. It produces hallucinogenic or psychedelic effects. Because of the low potency of 2C-O-4, and the inactivity of 2C-O, Shulgin felt that the 2C-O series would not be an exciting area for research, and did not pursue any further analogues.

Use and effects

Little is known about the psychopharmacological effects of 2C-O-4. Based on the one report available in his book PiHKAL, Shulgin lists the dose of 2C-O-4 as being greater than 60mg orally. At 60mg, threshold psychoactive effects occurred. These included awareness of something in the front part of the head, yawning, physiological changes, and a general exhilaration and excitement. The effects lasted a few hours and were rated as a +1 on the Shulgin Rating Scale. The drug was regarded as remaining to be fully explored.

Pharmacology

Pharmacodynamics

The pharmacology of 2C-O-4 analogues has been studied.

Chemistry

2C-O-4 is in a class of compounds commonly known as phenethylamines, and the systematic chemical name is 2-ethanamine.

Society and culture

Legal status

Canada

As of October 31, 2016, 2C-O-4 is a controlled substance in Canada.

United States

2C-O-4 is unscheduled and unregulated in the United States; however, because of its close similarity in structure and effects to mescaline and 2C-T-7, possession and sale of 2C-O-4 may be subject to prosecution under the Federal Analog Act.