2021 Chile Open

The 2021 Chile Open was a men's tennis tournament played on outdoor clay courts. It was the 23rd edition of the Chile Open, and part of the ATP 250 of the 2021 ATP Tour. It took place in Santiago, Chile from 8 through 14 March 2021.

Champions

Singles

Cristian Garín def. Facundo Bagnis, 6–4, 6–7, 7–5
Doubles
Simone Bolelli / Máximo González def. Federico Delbonis / Jaume Munar, 7–6, 6–4
Singles main draw entrants

Seeds

Country

Player

Rank¹

Seed

Chile

Other entrants

The following players received wildcards into the singles main draw:

The following player received special exemption into the singles main draw:

Francisco Cerúndolo

The following players received entry from the qualifying draw:

Sebastián Báez
Holger Rune
Alejandro Tabilo
Juan Pablo Varillas
Withdrawals
Fabio Fognini → replaced by Jaume Munar
Miomir Kecmanović → replaced by Andrej Martin
Dominik Koepfer → replaced by Daniel Elahi Galán
Juan Ignacio Londero → replaced by Facundo Bagnis
Pedro Martínez → replaced by Daniel Altmaier
Thiago Monteiro → replaced by Jozef Kovalík
Guido Pella → replaced by Pedro Sousa
Doubles main draw entrants

Seeds

¹ Rankings are as of March 1, 2021
Other entrants

The following pairs received wildcards into the doubles main draw:

Marcelo Tomás Barrios Vera / Alejandro Tabilo
Nicolás Jarry / Leonardo Mayer
Withdrawals

;Before the tournament

Federico Delbonis / Juan Ignacio Londero → replaced by Federico Delbonis / Jaume Munar