2-Methoxyphenethylamine


2-Methoxyphenethylamine is a drug of the phenethylamine family. It is one of the methoxyphenethylamine positional isomers.

Use and effects

The effects of 2-MPEA in humans have not been reported and are unknown.

Pharmacology

The drug showed very low affinity for the serotonin receptors in the rat stomach fundus strip. In another study, it showed no affinity for the serotonin 5-HT2A or 5-HT2C receptors. 2-MPEA is a potent full agonist of the human trace amine-associated receptor 1 .

History

2-MPEA was first described in the scientific literature by at least 1943. It was included as an entry in Alexander Shulgin's 2011 book The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds.