1-Indanone


1-Indanone is the organic compound with the formula C6H42CO. It is one of two isomeric benzocyclopentanones, the other being 2-indanone. It is a colorless solid. 1-Indanone is a substrate for the enzyme indanol dehydrogenase.

Preparation

It is prepared by oxidation of indane or indene. It can also be prepared by cyclization of phenylpropionic acid.

Uses and reactions

1-Indanone is an intermediate in the synthesis of a variety of pharmaceutical drugs including 2-aminoindane, drinidene, pirandamine, and pyrophendane.
1-Indanol can be produced by hydride reduction of 1-indanone.