William Spicer
William Spicer may refer to:
- William Spicer (14th-century MP), MP for Devizes
- William A. Spicer, Seventh-day Adventist minister and president of the General Conference of Seventh-day Adventists
- William C. Spicer, American college football player and coach
- William E. Spicer, American engineering academic
- William L. Spicer, American businessman and state chairman of the Arkansas Republican Party
- William Spicer (cricketer), English cricketer
- William Spicer (Medal of Honor), gunner's mate in the United States Navy who received the Medal of Honor
- William Spicer (MP for Exeter), British MP for Exeter, 1767–1768