William Middleton
William Middleton may refer to:
Politicians
- William Middleton, MP for Carlisle
- Sir William Middleton, 3rd Baronet, British Member of Parliament for Northumberland, 1722–1757
- Sir William Middleton, 5th Baronet, British Member of Parliament for Northumberland, 1774–1795
- Sir William Fowle Middleton, 1st Baronet, British Member of Parliament for Ipswich and Hastings
Others
- William Middleton , medieval bishop of Norwich
- William Middleton , English churchman, academic and Protestant controversialist
- George "Bay" Middleton, equerry to John Spencer, 5th Earl Spencer
- William Shainline Middleton, American internist
- William James Middleton, World War I flying ace
- William D. Middleton, author, reporter and photographer
- William Middleton , American football cornerback
- William Middleton, journalist and writer
- Billy Middleton, English football forward