William Knox
William Knox may refer to:
Australia
- William Dunn Knox, Australian artist
- William Knox (Victorian politician), Australian politician - House
- William Knox (Queensland politician), Australian state politician - Legislative Assembly
United Kingdom
- William Knox (Scottish poet), Scottish poet and journalist
- William Knox D'Arcy, British entrepreneur
- William Knox (footballer, fl. 1927–1934), Scottish professional footballer
- William Knox (footballer, born 1904), Scottish professional footballer
- William Knox (MP), MP for Dungannon
- William Knox (British Army officer), British general
- William Knox (bishop), Bishop of Killaloe and Kilfenora
- William Knox (artist), British artist of marine paintings and scenes of Venice
- William Knox (cricketer), Scottish cricketer
- Bill Knox, Scottish author
- Willie Knox, Scottish professional footballer and manager
United States
- Frank Knox, American Secretary of the Navy
- William F. Knox, American football player and coach and lawyer
- William Jacob Knox Jr., African-American chemist, worked on the Manhattan Project
- William J. Knox, California businessman and politician
- William Shadrach Knox, American congressman from Massachusetts
- William W. Knox, U.S. federal judge