William Chase
William Chase may refer to:
- William Merritt Chase, American painter
- William Calvin Chase, African-American lawyer and newspaper editor
- William Martin Chase, justice of the Supreme Court of New Hampshire
- William C. Chase, American general
- William Henry Chase, Florida militia colonel
- William J.J. Chase, American architect of Atlanta, Georgia
- William St Lucien Chase, recipient of the Victoria Cross
- William Chase (entrepreneur), founder of the Tyrrells crisp brand
- William Henry Chase (Canadian entrepreneur), entrepreneur and philanthropist in Nova Scotia, Canada
- Robert William Chase, British ornithologist