Vita-Man first appears on the back cover of Big Bang #0 starring in the fictionalRed Hot Comics #14. After numerous reader requests to see Vita-Man in action, he finally gets his own story in Big Bang Comics #27.
Vita-Man is research scientistWill Wheeler, who discovered a new vitamin that gave him superpowers, which he named "Panacea Pills", the name given to the vitamins after his father created them. With this, he became the superhero Vita-Man, and later joined the Knights of Justice alongside Ultiman, Venus and Dr. Stellar.