Ventilatory constraints influence physiological dead space in heart failure
Ventilatory constraints influence physiological dead space in heart failure is a scholarly work by Joshua R Smith, published in 2018 in ''Experimental Physiology''. The main subjects of the publication include mechanical ventilation, dead space, cardiology, ejection fraction, exercise physiology, medicine, respiratory minute volume, tidal volume, ventilation, anaesthesia, chronic obstructive pulmonary disease, internal medicine, and heart failure. New Findings What is the central question of this study? The goal of this study was to investigate the effect of alterations in tidal volume and alveolar volume on the elevated physiological dead space and the contribution of ventilatory constraints thereof in heart failure patients during submaximal exercise. What is the main finding and its importance? We found that physiological dead space was elevated in heart failure via reduced tidal volume and alveolar volume.