Triadimefon


Triadimefon is a fungicide used in agriculture to control various fungal diseases. As a seed treatment, it is used on barley, corn, cotton, oats, rye, sorghum, and wheat. In fruit it is used on pineapple and banana. Non-food uses include pine seedlings, Christmas trees, turf, ornamental plants, and landscaping.

Pharmacology

Estrogenic effect, inhibition of aromatase activity, decrease of estrogens production and increase androgens availability.
Triadimefon potently inhibited rat’s neurosteroidogenic enzymes, 5α-Red1 and 3α-HSD.
Dopamine as well as serotonergic pathways are involved.
Psychomotor stimulatory. Anti-estrogen effect.