The Thomas C. Wilkinson House is an Italian Villa style home that sits on a large lot high above street level. The two-story house is frame construction with a front gable, L-plan main block. It features a three-stage, square tower. The third level is not original to the house. The windows on the west wing appear to be from the turn of the 20th century and suggest this portion of the house was built later than the rest of the structure. The house features a bracketed cornice on the main block, an entrance porch with a spindle frieze and wrought iron railings. The main façade has two round-arched windows on both levels. The lower-level windows are taller than the upper-level windows and they all feature muntins. There are two circular windows above the ground level in the basement.