The effect of electrostatics on factor H function and related pathologies
The effect of electrostatics on factor H function and related pathologies is a scholarly work by Chris A. Kieslich and Dimitrios Morikis, published in 2011 in ''Journal of Molecular Graphics & Modelling''. The main subjects of the publication include chemistry, biophysics, complement system, cluster analysis, electrostatics, hemoglobinopathy, static electricity, CFH, biological function, binding site, thrombosis, and chemical physics. The authors present a model of non-specific electrostatic interactions of FH with polyanion-rich surfaces and specific interactions with C3b, using the authors' computational data and existing experimental data.