TRNA(His) guanylyltransferase
tRNA guanylyltransferase is an enzyme with systematic name p-tRNA:GTP guanylyltransferase . This enzyme catalyses the following chemical reaction
The enzyme requires a divalent cation for activity.
Thg1 enzymes are the only nucleic acid polymerases known to be capable of catalyzing nucleotide addition in the 3′–5′ direction.