Synaptic pharmacology


Synaptic pharmacology is the study of drugs that act on the synapses. It deals with the composition, uses, and effects of drugs that may enhance or diminish activity at the synapse, which is the junction across which a nerve impulse passes from an axon terminal to a neuron, muscle cell, or gland cell.
A partial list of pharmacological agents that act at synapses follows.
Channel, Receptor, or PhenomenonAntagonist or Blocker
adenosineDCPGX, ZM241385, anoxinine
AMPA-RNBQX
AMPA-R desensitizationcyclothiazide
cannabinoidAM-251
GABAAbicuculline, gabazine
GABABCGP-54626
glycinestrychnine
kainate R..
metabotropic GluR, broadMCPG, pertussis toxin, NEM
muscarinic AChRatropine, Scopolamine
nicotinic AChRbungarotoxin, curare, DhBe
NMDA-RAPV